UC Irvine researchers develop framework to make CAR T-cell therapy safer
CAR T-cell therapy has transformed cancer care, offering new hope to patients with aggressive blood cancers who once…
Polydatin reduces ulcerative colitis by regulating intestinal immune cells
Ulcerative colitis (UC) is a chronic inflammatory bowel disease in which recurrent intestinal inflammation can be difficult to…
New study redefines high risk criteria for multiple myeloma
Researchers have found that with new treatments for multiple myeloma, a serious type of blood cancer, clinicians should…
AI-designed molecular switch uses caffeine to control engineered cells
For many of us, a warm cup of coffee is how we start our day. For Texas A&M…
Maternal screening could help prevent deadly forms of leukemia
A deadly form of leukemia may be stopped before it ever develops by introducing targeted maternal screening in…
Why H2N2 flu is back on the pandemic preparedness radar
Decades after H2N2 vanished from humans, declining immunity and persistent animal reservoirs are renewing calls for stockpile-ready vaccines…
Researchers uncover new mechanism linking metabolism, immunity, and skeletal health
Obesity alters bone health not only through increased body weight but also by reshaping the bone marrow environment.…
Scientists find unexpected immune pathways for mRNA cancer vaccines
The advent of mRNA vaccines against SARS-CoV-2 in 2020 changed the course of the COVID-19 pandemic. Now, the…
How the nutrient cysteine controls cancer-fighting power of T cells
A research team from the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School…
Microbial ecosystems influence success of cancer checkpoint immunotherapy
Immune checkpoint inhibitors targeting PD-1 and PD-L1 have revolutionized cancer therapy, delivering long-term survival benefits in several malignancies.…
Silica nanomatrix enhances immunotherapy for solid tumors
Cancer has long remained a leading cause of death worldwide and in Hong Kong, accounting for 30% of…
Review highlights emerging role of tumor MHC-II in shaping cancer immunotherapy outcomes
Cancer immunotherapy has transformed cancer treatment, yet many patients experience limited or short-lived responses due to immune evasion,…