New findings show why the human intestine uniquely presents gluten to T cells
New evidence shows that human M cells act as fully fledged antigen-presenting cells, processing and presenting gluten peptides…
Review highlights emerging role of tumor MHC-II in shaping cancer immunotherapy outcomes
Cancer immunotherapy has transformed cancer treatment, yet many patients experience limited or short-lived responses due to immune evasion,…
Dietary restriction boosts antitumour immunity by rewiring T cell metabolism
By elevating ketone-driven energy pathways inside CD8+ T cells, dietary restriction steers them away from exhaustion and toward…
Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer
Triple-negative breast cancer (TNBC) is one of the most aggressive and treatment-resistant forms of breast cancer. It grows…
New analysis reveals fundamental flaws in widely used measures of biological aging
A landmark review published today in Genomic Psychiatry challenges researchers to fundamentally reconsider how the field measures and…
A personalized approach to treating pancreatic cancer
Research Matters: Personalizing Pancreatic Cancer TreatmentPlay Video Credit: Weill Cornell Medicine It’s not surprising that pancreatic cancer is often…
The future of cancer detection could be just a blood test away, say scientists
The prospect of diagnosing cancer through painless methods—such as a simple AI-assisted blood or urine test that detects…
AR3-based optogenetic strategy shows high efficacy in inducing apoptosis and antitumor effects
One of the hallmarks of cancer cells is their ability to evade apoptosis, or programmed cell death, through…
RFK Jr. wants to delay the hepatitis B vaccine. Here’s what parents need to know.
Working out of a tribal-owned hospital in Anchorage, Alaska, liver specialist Brian McMahon has spent decades treating the…
Innate immunity and metabolic stress drive a unique form of cell death
In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together. A study…
Study reveals ATM kinase as the key driver of replicative senescence
After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres-the…
Hematological and biochemical indicators show growing value in breast cancer management
Breast cancer remains a predominant global health challenge for women, with late-stage diagnosis being a key contributor to…