PTGES3 emerges as key regulator of androgen receptor in prostate cancer
A poorly characterized protein, historically thought to be a chaperone or enzyme, may actually be a key player…
Trojan horse strategy using cesium nanosalts shows powerful anti-cancer effects
Recently, a team led by Academician Hongjie Zhang, Researcher Shuyan Song, Associate Researcher Pengpeng Lei, and Dr. Ran An…
Northwestern team develops antibody to expose hidden pancreatic cancer cells
Pancreatic cancer is notoriously hard to treat and often resists the most advanced immunotherapies. Northwestern Medicine scientists have…
precision DNA repair may hold clues for human aging
The bowhead whale’s remarkable lifespan and low cancer risk stem from a finely tuned DNA repair system driven…
Intraoperative radiation reduces the recurrence rate of pancreatic cancer
Using targeted radiation during surgery – referred to as intraoperative radiation – to eliminate pancreatic cancer cells that…
Two microbial metabolites compete to control the cells’ protein building machinery
The microbiome-the trillions of bacteria, viruses, and fungi that live quietly in our body-plays a crucial role in…
Two analgesic drugs may one day be repurposed as anti-tumor therapies
Peripheral afferent neurons – nerves that send signals from all areas of the body to the central nervous…
Preliminary study shows intraoperative radiation’s success against pancreatic cancer spread
Using targeted radiation during surgery – referred to as intraoperative radiation – to eliminate pancreatic cancer cells that…
Mitochondria and lysosomes work together to control regulatory T cell activation
Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the…
How COVID mRNA vaccines may make cancer treatments more effective
A new study reveals that SARS-CoV-2 mRNA vaccines can amplify immune checkpoint therapy in lung and skin cancers…
Drug shows striking success in treating children with multi-metastatic Ewing sarcoma
Ewing sarcoma is one of the most common bone cancers seen in children, and if it spreads, it…
Researchers develop a novel approach to monitor CD8⁺ T cell activity over time
The ability of immune cells-particularly CD8+ T cells-to launch a rapid burst of proliferation inside tumors is key…