New genome-wide CRISPR screening tool boosts natural killer cells to fight cancer
Natural killer (NK) cells became markedly better at killing cancer cells after scientists removed key gene targets identified…
UCSF researchers uncover how breast cancer steals energy from fat cells
UCSF scientists caught cancer cells in the act of breaking into fat cells and releasing their fat. The…
Targeting a sugar metabolism pathway offers hope for treating rare and aggressive childhood cancer
A new study delving into the genetic drivers of a rare and aggressive childhood cancer called Malignant Peripheral…
Mitochondrial metabolite glutathione plays key role in breast cancer metastasis
The mitochondria may be the powerhouse of the cell, but mounting evidence suggests this organelle is also a…
Missing messenger RNA fragments unlock new immunotherapy targets in pediatric brain tumors
A new study, led by researchers at Children’s Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA…
Lactylation drives tumor progression and immune evasion in triple negative breast cancer
Breast cancer maintains its position as the most prevalent malignancy in women worldwide, with triple-negative breast cancer (TNBC)…
Amino acid metabolism shapes the tumor immune microenvironment and therapy response
The tumor microenvironment is not just a site of cancer growth—it is a high-stakes metabolic contest where tumor…