Ireland
  • Europe
  • Headlines
  • Ireland
  • World
  • Business
  • Technology
  • Entertainment
  • Sports
  • Science
  • Health

Categories

  • Artificial intelligence
  • Arts and design
  • Books
  • Business
  • Celebrities
  • Computing
  • Economy
  • Entertainment
  • Entrepreneurship
  • Environment
  • Fitness
  • Gadgets
  • Genetics
  • Headlines
  • Health
  • Healthcare
  • Internet
  • Ireland
  • Jobs
  • Markets
  • Medication
  • Mental health
  • Mobile
  • Movies
  • Music
  • Nutrition
  • Personal finance
  • Physics
  • Science
  • Space
  • Sports
  • Technology
  • TV
  • Virtual reality
  • Wildlife
  • World
Ireland
  • Europe
  • Headlines
  • Ireland
  • World
  • Business
  • Technology
  • Entertainment
  • Sports
  • Science
  • Health

Browsing Tag

Vascular

35 posts
TTechnology
Fentanyl abuse impairs cardiac cell function and contributes to heart rhythm defects
Read More

Immune system dysfunction may fuel progressive heart failure after heart attacks

  • January 28, 2026
When the heart’s muscle is weakened or injured due to a heart attack, it can make it hard…
HHealth
Living in food deserts linked to higher stroke and death risk in atrial fibrillation patients
Read More

New 2026 guideline expands access to advanced acute ischemic stroke care

  • January 27, 2026
Expanded eligibility for advanced stroke therapies and new recommendations for diagnosing and treating stroke in children and adults are among…
HHealth
Compact bNIRS technology could become a diagnostic toolkit for dementia
Read More

High BMI linked to vascular dementia risk

  • January 22, 2026
High body mass index (BMI) could cause a higher risk of vascular-related dementia (a combination of vascular +…
HHealth
Amino acid metabolism shapes the tumor immune microenvironment and therapy response
Read More

Decoupling of metabolism and vasculature in tumors revealed by novel Capillary-Cell microscopy

  • January 21, 2026
A multidisciplinary team from Harvard Medical School, Duke University, and Massachusetts General Hospital has developed the dual-scale Capillary-Cell…
HHealth
AI voice agents helped improve accuracy of blood pressure measurements in older adults
Read More

Thermogenic beige fat protects blood vessels from hypertension

  • January 16, 2026
Obesity causes hypertension. Hypertension causes cardiovascular disease. And cardiovascular disease is the leading cause of death worldwide. While…
HHealth
Blocking platelet-activating factor reduces liver damage in cirrhosis
Read More

Blocking platelet-activating factor reduces liver damage in cirrhosis

  • December 21, 2025
Researchers from Miguel Hernández University of Elche (UMH) in Spain have identified an effective strategy to reduce structural…
HHealth
Compact bNIRS technology could become a diagnostic toolkit for dementia
Read More

Study identifies molecular drivers of cerebral small vessel disease

  • December 16, 2025
A new study identifies molecular factors that promote small vessel disease – and an active drug that can…
SScience
Researchers discover how plants produce cancer-fighting mitraphylline
Read More

Glycation stress drives aortic stiffening through oxidative stress and senescence

  • December 13, 2025
A new research paper was published in Volume 17, Issue 11 of Aging-US on November 14, 2025, titled “Methylglyoxal-induced glycation stress…
HHealth
Cellular responses to ischemic reperfusion injury in young vs older donor organs. During ischemia, the deprivation of oxygen and nutrients leads to mitochondrial dysfunction and energy loss. In young cells, mitochondrial resilience helps sustain ATP production, ameliorating damage. Old cells, in contrast, experience significant ATP depletion, relying heavily on anaerobic metabolism, which leads to lactate buildup, pH reduction, and cellular stress. Upon reperfusion, the restoration of blood flow triggers oxidative stress as mitochondria generate excessive reactive oxygen species (ROS). Young cells compensate for those events through robust antioxidant systems, maintaining cellular integrity. Conversely, in old cells, impaired antioxidant defenses result in unregulated ROS production, furthermore damaging membranes, organelles, and DNA. Additionally, old cells release pro-inflammatory genes, amplifying local inflammation. Consequences are particularly severe in aged vascular endothelial cells, with ion pump dysfunction (e.g., Na⁺/K⁺ ATPase) causing ionic imbalances and cellular edema. This disruption exacerbates ischemic injury, progressing to irreversible damage. In contrast, young cells effectively resolve edema and inflammation through mechanisms that include macrophage945 mediated clearance of Damage-Associated Molecular Patterns (DAMPs) and anti-inflammatory cytokine release (e.g., IL-10 and TGF-β), allowing recovery and tissue repair. In old cells, persistent ROS generation, unresolved inflammation, and DAMP accumulation lead to irreversible inflammation, organelle collapse, and eventual cell death. Created in BioRender. Kayumov, M. (2025) https://BioRender.com/m23u7ro .
Read More

Scientists outline how organ rejuvenation strategies could solve the donor shortage

  • December 12, 2025
New insights into cellular aging, perfusion technologies, and senescence-targeting treatments show how aging organs could be revived, turning…
HHealth
Less education associated with faster aging and health inequality
Read More

New analysis reveals fundamental flaws in widely used measures of biological aging

  • December 4, 2025
A landmark review published today in Genomic Psychiatry challenges researchers to fundamentally reconsider how the field measures and…
HHealth
Experimental drug engasertib shows promise for treating inherited bleeding disorder
Read More

Experimental drug engasertib shows promise for treating inherited bleeding disorder

  • November 27, 2025
Hereditary hemorrhagic telangiectasia (HHT) is the second most common inherited bleeding disorder worldwide, affecting 1 in 3,800 persons.…
HHealth
Mitochondrial dysfunction in the blood-brain barrier may contribute to neuropsychiatric disease in 22qDS
Read More

Obesity-related metabolic stress may affect brain health far earlier than expected

  • November 26, 2025
For decades, scientists have known that what harms the body often harms the brain. Conditions such as obesity,…
Ireland
www.europesays.com