Detailed images reveal DNA repair mechanism in cancer-related proteins
Scientists have captured the most detailed structural images to date of a specific type of protein’s DNA repair…
Epigenome proteins shape dynamic gene expression beyond simple on-off
A new study finds the proteins responsible for controlling which genes are expressed in a genome do more…
Study reveals dual role of PFK enzyme in metabolism and cell cycle progression
A metabolic enzyme studied for over seven decades has a hidden second function – it can unwind RNA…
New catalog identifies dozens of plasma membrane repair proteins
In the evolutionary history of life, the ability of a cell to separate its inner world from the…
Transposable elements cause majority of lethal mutations in fruit flies
Most lethal mutations in wild fruit flies are driven by newly transferred jumping genes, not small DNA errors,…
Study sheds light on behavior of yeast cells in the gut
A new study sheds light on the behavior of yeast cells in the gut, paving the way for…
NUS scientists transform kombu into a probiotic superfood with fruity aromas
Kombu (Saccharina japonica) is a brown seaweed extensively cultivated and consumed in Japan, Korea and China. Despite its…
A yeast-derived genetic tool offers hope for mitochondrial disorders and cancer
Nucleotide synthesis-the production of the basic components of DNA and RNA-is essential for cell growth and division. In…
Opposing protein forces fine tune mRNA stability in human cells
A newly revealed molecular tug-of-war may have implications for better understanding how a multitude of diseases and disorders…
Understanding how the immune system protects against fungal pathogenicity
The yeast Candida albicans colonizes mucosal surfaces and is usually harmless. However, under certain conditions it can cause…
Breakthrough platform reveals the choreography of mammalian transcription
Life’s instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads…
Baker’s Yeast Can Survive Mars-like Stress Conditions, New Study Shows
Exploring the possibility of the survival of life under extraterrestrial conditions is an important goal of astrobiology. In…