{"id":134145,"date":"2025-10-20T15:20:13","date_gmt":"2025-10-20T15:20:13","guid":{"rendered":"https:\/\/www.europesays.com\/ie\/134145\/"},"modified":"2025-10-20T15:20:13","modified_gmt":"2025-10-20T15:20:13","slug":"world-record-set-for-fastest-genome-sequencing-health-2","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/ie\/134145\/","title":{"rendered":"World Record Set For Fastest Genome Sequencing | Health"},"content":{"rendered":"<p>                                <strong>Key Takeaways<\/strong><\/p>\n<ul>\n<li>\n<p>Researchers have set a new world record for fastest whole human genome sequencing<\/p>\n<\/li>\n<li>\n<p>The team completed a sequence in just under four hours, breaking the previous record of just over five hours<\/p>\n<\/li>\n<li>\n<p>Same-day genome analysis could help steer treatment of sick newborns\u00a0<\/p>\n<\/li>\n<\/ul>\n<p>FRIDAY, Oct. 17, 2025 (HealthDay News) \u2014 A new Guinness World Record for fastest whole human genome sequencing has been achieved, with researchers breaking down a patient\u2019s genetic profile in less than four hours.<\/p>\n<p>The 3-hour 57-minute analysis surpassed the previous record of 5 hours and 2 minutes, researchers reported Oct. 15 in <a href=\"https:\/\/www.nejm.org\/doi\/10.1056\/NEJMc2512825\" rel=\"nofollow noopener\" target=\"_blank\">The<\/a> <a href=\"https:\/\/www.nejm.org\/doi\/10.1056\/NEJMc2512825\" rel=\"nofollow noopener\" target=\"_blank\"><a href=\"https:\/\/www.nejm.org\/doi\/10.1056\/NEJMc2512825\" rel=\"nofollow noopener\" target=\"_blank\">New England Journal of Medicine<\/a><a href=\"https:\/\/www.nejm.org\/doi\/10.1056\/NEJMc2512825\" rel=\"nofollow noopener\" target=\"_blank\">.<\/a><\/p>\n<p>This breakthrough is one step closer to making same-day genetic analysis available for patients in crisis, researchers said.<\/p>\n<p>Specifically, the advance could make it easier to craft targeted treatments for critically ill babies in the neonatal intensive care unit (NICU) based on their genetics, researchers said.<\/p>\n<p>\u201cOur pilot simulates a workflow through which we could feasibly send out a genome sequencing sample from a baby in the morning and have the diagnosis\/report that same afternoon,\u201d said lead researcher <a href=\"https:\/\/www.childrenshospital.org\/directory\/monica-wojcik\" rel=\"nofollow noopener\" target=\"_blank\">Dr. Monica Wojcik<\/a>, an attending physician in newborn medicine and genetics and genomics at Boston Children\u2019s Hospital.<\/p>\n<p>\u201cThis would truly be game-changing for rare disease diagnoses for our families, who are currently waiting for a week \u2014 at best \u2014 for diagnoses for their critically ill babies,\u201d Wojcik said in a news release. \u201cIn the NICU, a few hours could mean the difference between unnecessary procedures and targeted, life-saving treatment.\u201d<\/p>\n<p>Whole genome sequencing involves analyzing all of a person\u2019s genetics, translating all of the 3 billion DNA base pairs that contribute to each individual\u2019s being, according to <a href=\"https:\/\/www.yalemedicine.org\/conditions\/whole-genome-sequencing\" rel=\"nofollow noopener\" target=\"_blank\">Yale Medicine<\/a>.<\/p>\n<p>Doctors can use such sequencing to find mutations in a person\u2019s genetics that could be contributing to health problems or abnormalities.<\/p>\n<p>For the study, researchers sequenced and analyzed 15 children\u2019s genomes at a rate of one or two per day, using next-generation sequencing technology developed by the pharmaceutical company Roche.<\/p>\n<p>The samples included five historical cases from the Boston Children\u2019s Manton Center for Orphan Disease Research, and seven straight from the Boston Children\u2019s NICU.<\/p>\n<p>The new tech, called sequencing by expansion (SBX), \u201cwas engineered for speed, accuracy and reliability,\u201d <a href=\"https:\/\/diagnostics.roche.com\/global\/en\/contributors\/mark-kokoris.html\" rel=\"nofollow noopener\" target=\"_blank\">Mark Kokoris<\/a>, head of SBX Technology at Roche Sequencing Solutions, said in a news release.<\/p>\n<p>\u201cAchieving a sample to result in less than four hours shows what\u2019s possible when cutting-edge chemistry, instrumentation and analysis pipelines work in concert,\u201d added Kokoris, who was not involved in the study.<\/p>\n<p>On average, researchers completed the whole genome sequencing within 4 hours 4 minutes, with the longest analysis taking 4 hours 25 minutes.<\/p>\n<p>Blood samples that arrived in the lab by 7 a.m. were returned with both an analysis and an interpretive report between 2 p.m. and 4:30 p.m. the same day.<\/p>\n<p>\u201cToday, we are able to sequence human genomes faster than they\u2019ve ever been done before,\u201d senior researcher <a href=\"https:\/\/broadclinicallabs.org\/leader\/niall-lennon-ph-d\/\" rel=\"nofollow noopener\" target=\"_blank\">Niall Lennon<\/a>, chair and chief scientific officer of Broad Clinical Labs, said in a news release.<\/p>\n<p>\u201cWe demonstrated that rapid sequencing and interpretation are achievable in a matter of hours, and that brings us one step closer to a future where genetic answers can inform urgent decisions at the bedside,\u201d Lennon said.<\/p>\n<p><strong>More information<\/strong><\/p>\n<p>Yale Medicine has more on <a href=\"https:\/\/www.yalemedicine.org\/conditions\/whole-genome-sequencing\" rel=\"nofollow noopener\" target=\"_blank\">whole genome sequencing<\/a>.<\/p>\n<p>SOURCES: Boston Children\u2019s Hospital, news release, Oct. 15, 2025; Broad Clinical Labs, news release, Oct. 15, 2025; New England Journal of Medicine, Oct. 15, 2025<\/p>\n<p><strong>What This Means For You<\/strong><\/p>\n<p>Same-day genome analysis could help save the lives of sick newborns suffering from gene-related illnesses.<\/p>\n","protected":false},"excerpt":{"rendered":"Key Takeaways Researchers have set a new world record for fastest whole human genome sequencing The team completed&hellip;\n","protected":false},"author":2,"featured_media":134146,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[272],"tags":[14971,8414,3548,77445,8108,7593,50211,34525,11439,2562,18,77444,458,6872,135,475,7484,19,17,3544,77446,26535,96,1867,34270,133,12631],"class_list":{"0":"post-134145","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-genetics","8":"tag-animal-husbandry","9":"tag-biochemistry","10":"tag-bioinformatics","11":"tag-biological-engineering","12":"tag-biology","13":"tag-biotechnology","14":"tag-child-health","15":"tag-clinical-medicine","16":"tag-consumer-news","17":"tag-dna-sequencing","18":"tag-eire","19":"tag-general-health","20":"tag-genetics","21":"tag-genomics","22":"tag-health","23":"tag-health-care","24":"tag-health-sciences","25":"tag-ie","26":"tag-ireland","27":"tag-life-sciences","28":"tag-medical-diagnosis","29":"tag-medical-specialties","30":"tag-medicine","31":"tag-molecular-biology","32":"tag-omics","33":"tag-science","34":"tag-whole-genome-sequencing"},"share_on_mastodon":{"url":"","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/posts\/134145","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/comments?post=134145"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/posts\/134145\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/media\/134146"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/media?parent=134145"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/categories?post=134145"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/tags?post=134145"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}