{"id":13593,"date":"2025-08-21T09:52:09","date_gmt":"2025-08-21T09:52:09","guid":{"rendered":"https:\/\/www.europesays.com\/ie\/13593\/"},"modified":"2025-08-21T09:52:09","modified_gmt":"2025-08-21T09:52:09","slug":"vitamin-d-deficiency-tied-to-cataract-risk-in-young-adults","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/ie\/13593\/","title":{"rendered":"Vitamin D Deficiency Tied to Cataract Risk in Young Adults"},"content":{"rendered":"<p><strong>TOPLINE:<\/strong><\/p>\n<p>Severe deficiency of vitamin D (<\/p>\n<p><strong>METHODOLOGY:<\/strong><\/p>\n<ul>\n<li>Researchers examined cross-sectional and longitudinal associations between serum levels of 25-hydroxyvitamin D and the risk for cataracts, using data from the UK Biobank.<\/li>\n<li>The cross-sectional analysis included 442,255 participants with data on serum levels of vitamin D; among them, 427,923 participants (mean age, 56.2 years; 53.6% women) without cataracts at baseline were followed up for an average duration of 10.8 years in the longitudinal analysis.<\/li>\n<li>Based on serum levels of vitamin D at baseline, participants were categorized into those with severe deficiency (<\/li>\n<li>Cases of cataracts were confirmed from hospital records and self-reported information.<\/li>\n<\/ul>\n<p><strong>TAKEAWAY:<\/strong><\/p>\n<ul>\n<li>Of the 442,255 participants in the cross-sectional analysis, 3.24% had cataracts, and of the 427,923 participants in the longitudinal analysis, 13.02% developed the condition.<\/li>\n<li>In cross-sectional analyses, individuals with vitamin D levels <\/li>\n<li>In the longitudinal analysis, participants with vitamin D levels below 25 nmol\/L had an 11% higher risk of developing cataracts than those with levels of 50-74.9 nmol\/L (aHR, 1.11; 95% CI, 1.07-1.15); the risk was even greater among people younger than 50 years (aHR, 1.27; 95% CI, 1.07-1.49), whereas those aged 60 years or older had a 9% increased risk (aHR, 1.09; 95% CI, 1.04-1.14).<\/li>\n<\/ul>\n<p><strong>IN PRACTICE:<\/strong><\/p>\n<p>\u201cThe study identified significant cross-sectional and prospective associations between vitamin D deficiency and increased cataract risk, with younger individuals being more susceptible,\u201d the researchers reported. \u201cThese findings suggest a potential critical period in early adulthood when vitamin D supplementation may be most effective for cataract prevention, warranting further investigation into age-specific intervention strategies,\u201d they added.<\/p>\n<p><strong>SOURCE:<\/strong><\/p>\n<p>This study was led by Yu Peng and Yuzhou Zhang, of the Chinese University of Hong Kong, Hong Kong, China. It was published <a href=\"https:\/\/bjo.bmj.com\/content\/early\/2025\/08\/18\/bjo-2024-326716.info\" rel=\"nofollow noopener\" target=\"_blank\">online<\/a> on August 18, 2025, in the British Journal of Ophthalmology.<\/p>\n<p><strong>LIMITATIONS:<\/strong><\/p>\n<p>Not all cases of cataract may have been identified in this study. This study relied on baseline measurement of vitamin D levels, which did not account for variations during the follow-up period. The findings may not be generalizable to other populations as nearly 95% of participants in the UK Biobank were of White ethnicity.<\/p>\n<p><strong>DISCLOSURES:<\/strong><\/p>\n<p>This study was supported partly by the General Research Fund, Research Grants Council, Hong Kong; Collaborative Research Fund; Health and Medical Research Fund, Hong Kong; and other sources. The authors declared no conflicts of interest.<\/p>\n<p>This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.<\/p>\n","protected":false},"excerpt":{"rendered":"TOPLINE: Severe deficiency of vitamin D ( METHODOLOGY: Researchers examined cross-sectional and longitudinal associations between serum levels of&hellip;\n","protected":false},"author":2,"featured_media":13594,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[74],"tags":[291,289,7882,12730,612,18,12734,12733,7005,19,17,610,7881,7880,82,1294,12732,393,12731,5605],"class_list":{"0":"post-13593","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-technology","8":"tag-ai","9":"tag-artificial-intelligence","10":"tag-artificial-neural-networks","11":"tag-cataract","12":"tag-deep-learning","13":"tag-eire","14":"tag-electronic-health-record-ehr-electronic-health-record-ehr","15":"tag-hospital-records","16":"tag-hospitals","17":"tag-ie","18":"tag-ireland","19":"tag-machine-learning","20":"tag-ml-natural-language-processing","21":"tag-npl","22":"tag-technology","23":"tag-uk","24":"tag-uk-site-content-united-kingdom-site-content","25":"tag-united-kingdom","26":"tag-vitamin-d-deficiency","27":"tag-vitamins"},"share_on_mastodon":{"url":"","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/posts\/13593","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/comments?post=13593"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/posts\/13593\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/media\/13594"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/media?parent=13593"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/categories?post=13593"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/tags?post=13593"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}