{"id":198414,"date":"2025-11-24T23:43:13","date_gmt":"2025-11-24T23:43:13","guid":{"rendered":"https:\/\/www.europesays.com\/ie\/198414\/"},"modified":"2025-11-24T23:43:13","modified_gmt":"2025-11-24T23:43:13","slug":"haus6-as-a-potential-prognostic-and-immunological-biomarker-validation-from-pan-cancer-analysis-to-hepatocellular-carcinoma-cancer-cell-international","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/ie\/198414\/","title":{"rendered":"HAUS6 as a potential prognostic and immunological biomarker: validation from pan-cancer analysis to hepatocellular carcinoma | Cancer Cell International"},"content":{"rendered":"<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"1.\">\n<p class=\"c-article-references__text\" id=\"ref-CR1\">Burden of disease scenarios. For 204 countries and territories, 2022\u20132050: a forecasting analysis for the global burden of disease study 2021. Lancet. 2024;403(10440):2204\u201356.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 1\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=For%20204%20countries%20and%20territories%2C%202022%E2%80%932050%3A%20a%20forecasting%20analysis%20for%20the%20global%20burden%20of%20disease%20study%202021&amp;journal=Lancet&amp;volume=403&amp;issue=10440&amp;pages=2204-56&amp;publication_year=2024\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"2.\">\n<p class=\"c-article-references__text\" id=\"ref-CR2\">Sonkin D, Thomas A, Teicher BA. Cancer treatments: past, present, and future. Cancer Genet. 2024;286\u2013287:18\u201324.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 2\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Cancer%20treatments%3A%20past%2C%20present%2C%20and%20future&amp;journal=Cancer%20Genet&amp;volume=286%E2%80%93287&amp;pages=18-24&amp;publication_year=2024&amp;author=Sonkin%2CD&amp;author=Thomas%2CA&amp;author=Teicher%2CBA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"3.\">\n<p class=\"c-article-references__text\" id=\"ref-CR3\">Siegel RL, Kratzer TB, Giaquinto AN, Sung H, Jemal A. Cancer statistics, 2025. CA Cancer J Clin. 2025;75(1):10\u201345.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 3\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Cancer%20statistics%2C%202025&amp;journal=CA%20Cancer%20J%20Clin&amp;volume=75&amp;issue=1&amp;pages=10-45&amp;publication_year=2025&amp;author=Siegel%2CRL&amp;author=Kratzer%2CTB&amp;author=Giaquinto%2CAN&amp;author=Sung%2CH&amp;author=Jemal%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"4.\">\n<p class=\"c-article-references__text\" id=\"ref-CR4\">Qiong L, Shuyao X, Shan X, Qian F, Jiaying T, Yao X, et al. Recent advances in the glycolytic processes linked to tumor metastasis. Curr Mol Pharmacol. 2024;17:e18761429308361.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 4\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Recent%20advances%20in%20the%20glycolytic%20processes%20linked%20to%20tumor%20metastasis&amp;journal=Curr%20Mol%20Pharmacol&amp;volume=17&amp;publication_year=2024&amp;author=Qiong%2CL&amp;author=Shuyao%2CX&amp;author=Shan%2CX&amp;author=Qian%2CF&amp;author=Jiaying%2CT&amp;author=Yao%2CX\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"5.\">\n<p class=\"c-article-references__text\" id=\"ref-CR5\">Joyson P, Karanvir S, Sumit P, Rohit P, Shah Alam K, Bhupinder K, et al. An update on recently developed analytical and Bio-analytical methods for some anticancer drugs. Curr Pharm Anal. 2023;19(2):117\u201335.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 5\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=An%20update%20on%20recently%20developed%20analytical%20and%20Bio-analytical%20methods%20for%20some%20anticancer%20drugs&amp;journal=Curr%20Pharm%20Anal&amp;volume=19&amp;issue=2&amp;pages=117-35&amp;publication_year=2023&amp;author=Joyson%2CP&amp;author=Karanvir%2CS&amp;author=Sumit%2CP&amp;author=Rohit%2CP&amp;author=Shah%20Alam%2CK&amp;author=Bhupinder%2CK\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"6.\">\n<p class=\"c-article-references__text\" id=\"ref-CR6\">Karati D, Kumar D. Molecular insight into the apoptotic mechanism of cancer cells: an explicative review. Curr Mol Pharmacol. 2024;17:e18761429273223.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 6\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Molecular%20insight%20into%20the%20apoptotic%20mechanism%20of%20cancer%20cells%3A%20an%20explicative%20review&amp;journal=Curr%20Mol%20Pharmacol&amp;volume=17&amp;publication_year=2024&amp;author=Karati%2CD&amp;author=Kumar%2CD\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"7.\">\n<p class=\"c-article-references__text\" id=\"ref-CR7\">Yuwei Q, Ninghua Y, Fan Z, Shi Q, Xiaolei C, Wenjie Z. Tumor organoid model and its pharmacological applications in tumorigenesis prevention. Curr Mol Pharmacol. 2023;16(4):435\u201347.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 7\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Tumor%20organoid%20model%20and%20its%20pharmacological%20applications%20in%20tumorigenesis%20prevention&amp;journal=Curr%20Mol%20Pharmacol&amp;volume=16&amp;issue=4&amp;pages=435-47&amp;publication_year=2023&amp;author=Yuwei%2CQ&amp;author=Ninghua%2CY&amp;author=Fan%2CZ&amp;author=Shi%2CQ&amp;author=Xiaolei%2CC&amp;author=Wenjie%2CZ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"8.\">\n<p class=\"c-article-references__text\" id=\"ref-CR8\">Chen F, Wendl MC, Wyczalkowski MA, Bailey MH, Li Y, Ding L. Moving pan-cancer studies from basic research toward the clinic. Nat Cancer. 2021;2(9):879\u201390.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 8\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Moving%20pan-cancer%20studies%20from%20basic%20research%20toward%20the%20clinic&amp;journal=Nat%20Cancer&amp;volume=2&amp;issue=9&amp;pages=879-90&amp;publication_year=2021&amp;author=Chen%2CF&amp;author=Wendl%2CMC&amp;author=Wyczalkowski%2CMA&amp;author=Bailey%2CMH&amp;author=Li%2CY&amp;author=Ding%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"9.\">\n<p class=\"c-article-references__text\" id=\"ref-CR9\">Wang T, Yao S, Li S, Fei X, Zhang M. A prognostic model based on the augmin family genes for LGG patients. Sci Rep. 2023;13(1):7520.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 9\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=A%20prognostic%20model%20based%20on%20the%20augmin%20family%20genes%20for%20LGG%20patients&amp;journal=Sci%20Rep&amp;volume=13&amp;issue=1&amp;publication_year=2023&amp;author=Wang%2CT&amp;author=Yao%2CS&amp;author=Li%2CS&amp;author=Fei%2CX&amp;author=Zhang%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"10.\">\n<p class=\"c-article-references__text\" id=\"ref-CR10\">Tang L, Chen Z, Wei C, Liu H, Wang B, Yu T, et al. The significance of HAUS1 and its relationship with immune microenvironment in hepatocellular carcinoma. J Cancer. 2024;15(5):1328\u201341.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 10\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20significance%20of%20HAUS1%20and%20its%20relationship%20with%20immune%20microenvironment%20in%20hepatocellular%20carcinoma&amp;journal=J%20Cancer&amp;volume=15&amp;issue=5&amp;pages=1328-41&amp;publication_year=2024&amp;author=Tang%2CL&amp;author=Chen%2CZ&amp;author=Wei%2CC&amp;author=Liu%2CH&amp;author=Wang%2CB&amp;author=Yu%2CT\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"11.\">\n<p class=\"c-article-references__text\" id=\"ref-CR11\">Zhang X, Zhuang R, Ye Q, Zhuo J, Chen K, Lu D, et al. High expression of human augmincomplex submit 3 indicates poor prognosis and associates with tumor progression in hepatocellular carcinoma. J Cancer. 2019;10(6):1434\u201343.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 11\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=High%20expression%20of%20human%20augmincomplex%20submit%203%20indicates%20poor%20prognosis%20and%20associates%20with%20tumor%20progression%20in%20hepatocellular%20carcinoma&amp;journal=J%20Cancer&amp;volume=10&amp;issue=6&amp;pages=1434-43&amp;publication_year=2019&amp;author=Zhang%2CX&amp;author=Zhuang%2CR&amp;author=Ye%2CQ&amp;author=Zhuo%2CJ&amp;author=Chen%2CK&amp;author=Lu%2CD\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"12.\">\n<p class=\"c-article-references__text\" id=\"ref-CR12\">Ray D, Chatterjee N. A powerful method for pleiotropic analysis under composite null hypothesis identifies novel shared loci between type 2 diabetes and prostate cancer. PLoS Genet. 2020;16(12):e1009218.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 12\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=A%20powerful%20method%20for%20pleiotropic%20analysis%20under%20composite%20null%20hypothesis%20identifies%20novel%20shared%20loci%20between%20type%202%20diabetes%20and%20prostate%20cancer&amp;journal=PLoS%20Genet&amp;volume=16&amp;issue=12&amp;publication_year=2020&amp;author=Ray%2CD&amp;author=Chatterjee%2CN\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"13.\">\n<p class=\"c-article-references__text\" id=\"ref-CR13\">Zhu H, Fang K, Fang G. FAM29A, a target of Plk1 regulation, controls the partitioning of NEDD1 between the mitotic spindle and the centrosomes. J Cell Sci. 2009;122(Pt 15):2750\u20139.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 13\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=FAM29A%2C%20a%20target%20of%20Plk1%20regulation%2C%20controls%20the%20partitioning%20of%20NEDD1%20between%20the%20mitotic%20spindle%20and%20the%20centrosomes&amp;journal=J%20Cell%20Sci&amp;volume=122&amp;issue=Pt%2015&amp;pages=2750-9&amp;publication_year=2009&amp;author=Zhu%2CH&amp;author=Fang%2CK&amp;author=Fang%2CG\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"14.\">\n<p class=\"c-article-references__text\" id=\"ref-CR14\">Raji\u010di\u0107 M, Makunin A, Adna\u0111evi\u0107 T, Trifonov V, Vujo\u0161evi\u0107 M, Blagojevi\u0107 J. B chromosomes\u2019 sequences in yellow-necked mice Apodemus flavicollis-exploring the transcription. Life. 2021. <a href=\"https:\/\/doi.org\/10.3390\/life12010050\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.3390\/life12010050\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.3390\/life12010050<\/a>.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 14\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=B%20chromosomes%27%20sequences%20in%20yellow-necked%20mice%20Apodemus%20flavicollis-exploring%20the%20transcription&amp;journal=Life&amp;doi=10.3390%2Flife12010050&amp;publication_year=2021&amp;author=Raji%C4%8Di%C4%87%2CM&amp;author=Makunin%2CA&amp;author=Adna%C4%91evi%C4%87%2CT&amp;author=Trifonov%2CV&amp;author=Vujo%C5%A1evi%C4%87%2CM&amp;author=Blagojevi%C4%87%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"15.\">\n<p class=\"c-article-references__text\" id=\"ref-CR15\">MotieGhader H, Masoudi-Sobhanzadeh Y, Ashtiani SH, Masoudi-Nejad A. mRNA and MicroRNA selection for breast cancer molecular subtype stratification using meta-heuristic based algorithms. Genomics. 2020;112(5):3207\u201317.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 15\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=mRNA%20and%20MicroRNA%20selection%20for%20breast%20cancer%20molecular%20subtype%20stratification%20using%20meta-heuristic%20based%20algorithms&amp;journal=Genomics&amp;volume=112&amp;issue=5&amp;pages=3207-17&amp;publication_year=2020&amp;author=MotieGhader%2CH&amp;author=Masoudi-Sobhanzadeh%2CY&amp;author=Ashtiani%2CSH&amp;author=Masoudi-Nejad%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"16.\">\n<p class=\"c-article-references__text\" id=\"ref-CR16\">Goldman MJ, Craft B, Hastie M, Repe\u010dka K, McDade F, Kamath A, et al. Visualizing and interpreting cancer genomics data via the Xena platform. Nat Biotechnol. 2020;38(6):675\u20138.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 16\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Visualizing%20and%20interpreting%20cancer%20genomics%20data%20via%20the%20Xena%20platform&amp;journal=Nat%20Biotechnol&amp;volume=38&amp;issue=6&amp;pages=675-8&amp;publication_year=2020&amp;author=Goldman%2CMJ&amp;author=Craft%2CB&amp;author=Hastie%2CM&amp;author=Repe%C4%8Dka%2CK&amp;author=McDade%2CF&amp;author=Kamath%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"17.\">\n<p class=\"c-article-references__text\" id=\"ref-CR17\">Uhl\u00e9n M, Fagerberg L, Hallstr\u00f6m BM, Lindskog C, Oksvold P, Mardinoglu A, et al. Proteomics. Tissue-based map of the human proteome. Volume 347. New York, NY: Science; 2015. p. 1260419. 6220.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 17\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Proteomics.%20Tissue-based%20map%20of%20the%20human%20proteome&amp;publication_year=2015&amp;author=Uhl%C3%A9n%2CM&amp;author=Fagerberg%2CL&amp;author=Hallstr%C3%B6m%2CBM&amp;author=Lindskog%2CC&amp;author=Oksvold%2CP&amp;author=Mardinoglu%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"18.\">\n<p class=\"c-article-references__text\" id=\"ref-CR18\">Chandrashekar DS, Karthikeyan SK, Korla PK, Patel H, Shovon AR, Athar M, et al. Ualcan: an update to the integrated cancer data analysis platform, vol. 25. New York, NY: Neoplasia; 2022. p. 18\u201327.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 18\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Ualcan%3A%20an%20update%20to%20the%20integrated%20cancer%20data%20analysis%20platform&amp;pages=18-27&amp;publication_year=2022&amp;author=Chandrashekar%2CDS&amp;author=Karthikeyan%2CSK&amp;author=Korla%2CPK&amp;author=Patel%2CH&amp;author=Shovon%2CAR&amp;author=Athar%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"19.\">\n<p class=\"c-article-references__text\" id=\"ref-CR19\">Shen A, Liu L, Huang Y, Shen Z, Wu M, Chen X, et al. Down-Regulating HAUS6 suppresses cell proliferation by activating the p53\/p21 pathway in colorectal cancer. Front Cell Dev Biol. 2021;9:772077.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 19\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Down-Regulating%20HAUS6%20suppresses%20cell%20proliferation%20by%20activating%20the%20p53%2Fp21%20pathway%20in%20colorectal%20cancer&amp;journal=Front%20Cell%20Dev%20Biol&amp;volume=9&amp;publication_year=2021&amp;author=Shen%2CA&amp;author=Liu%2CL&amp;author=Huang%2CY&amp;author=Shen%2CZ&amp;author=Wu%2CM&amp;author=Chen%2CX\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"20.\">\n<p class=\"c-article-references__text\" id=\"ref-CR20\">Cerami E, Gao J, Dogrusoz U, Gross BE, Sumer SO, Aksoy BA, et al. The cbio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov. 2012;2(5):401\u20134.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 20\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20cbio%20cancer%20genomics%20portal%3A%20an%20open%20platform%20for%20exploring%20multidimensional%20cancer%20genomics%20data&amp;journal=Cancer%20Discov&amp;volume=2&amp;issue=5&amp;pages=401-4&amp;publication_year=2012&amp;author=Cerami%2CE&amp;author=Gao%2CJ&amp;author=Dogrusoz%2CU&amp;author=Gross%2CBE&amp;author=Sumer%2CSO&amp;author=Aksoy%2CBA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"21.\">\n<p class=\"c-article-references__text\" id=\"ref-CR21\">Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, et al. Protein Data Bank Nucleic Acids Res. 2000;28(1):235\u201342.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 21\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=&amp;journal=Protein%20Data%20Bank%20Nucleic%20Acids%20Res&amp;volume=28&amp;issue=1&amp;pages=235-42&amp;publication_year=2000&amp;author=Berman%2CHM&amp;author=Westbrook%2CJ&amp;author=Feng%2CZ&amp;author=Gilliland%2CG&amp;author=Bhat%2CTN&amp;author=Weissig%2CH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"22.\">\n<p class=\"c-article-references__text\" id=\"ref-CR22\">Modhukur V, Iljasenko T, Metsalu T, Lokk K, Laisk-Podar T, Vilo J. Methsurv: a web tool to perform multivariable survival analysis using DNA methylation data. Epigenomics. 2018;10(3):277\u201388.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 22\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Methsurv%3A%20a%20web%20tool%20to%20perform%20multivariable%20survival%20analysis%20using%20DNA%20methylation%20data&amp;journal=Epigenomics&amp;volume=10&amp;issue=3&amp;pages=277-88&amp;publication_year=2018&amp;author=Modhukur%2CV&amp;author=Iljasenko%2CT&amp;author=Metsalu%2CT&amp;author=Lokk%2CK&amp;author=Laisk-Podar%2CT&amp;author=Vilo%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"23.\">\n<p class=\"c-article-references__text\" id=\"ref-CR23\">Zhou Y, Zeng P, Li YH, Zhang Z, Cui Q. Sramp: prediction of mammalian N6-methyladenosine (m6A) sites based on sequence-derived features. Nucleic Acids Res. 2016;44(10):e91.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 23\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Sramp%3A%20prediction%20of%20mammalian%20N6-methyladenosine%20%28m6A%29%20sites%20based%20on%20sequence-derived%20features&amp;journal=Nucleic%20Acids%20Res&amp;volume=44&amp;issue=10&amp;publication_year=2016&amp;author=Zhou%2CY&amp;author=Zeng%2CP&amp;author=Li%2CYH&amp;author=Zhang%2CZ&amp;author=Cui%2CQ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"24.\">\n<p class=\"c-article-references__text\" id=\"ref-CR24\">Franz M, Rodriguez H, Lopes C, Zuberi K, Montojo J, Bader GD, et al. Genemania update 2018. Nucleic Acids Res. 2018;46(W1):W60-w4.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 24\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Genemania%20update%202018&amp;journal=Nucleic%20Acids%20Res&amp;volume=46&amp;issue=W1&amp;pages=W60-w4&amp;publication_year=2018&amp;author=Franz%2CM&amp;author=Rodriguez%2CH&amp;author=Lopes%2CC&amp;author=Zuberi%2CK&amp;author=Montojo%2CJ&amp;author=Bader%2CGD\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"25.\">\n<p class=\"c-article-references__text\" id=\"ref-CR25\">Tang Z, Kang B, Li C, Chen T, Zhang Z. Gepia2: an enhanced web server for large-scale expression profiling and interactive analysis. Nucleic Acids Res. 2019;47(W1):W556-60.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 25\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Gepia2%3A%20an%20enhanced%20web%20server%20for%20large-scale%20expression%20profiling%20and%20interactive%20analysis&amp;journal=Nucleic%20Acids%20Res&amp;volume=47&amp;issue=W1&amp;pages=W556-60&amp;publication_year=2019&amp;author=Tang%2CZ&amp;author=Kang%2CB&amp;author=Li%2CC&amp;author=Chen%2CT&amp;author=Zhang%2CZ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"26.\">\n<p class=\"c-article-references__text\" id=\"ref-CR26\">Wu T, Hu E, Xu S, Chen M, Guo P, Dai Z, et al. ClusterProfiler 4.0: a universal enrichment tool for interpreting omics data. Innovation (Cambridge (Mass)). 2021;2(3):100141.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 26\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=ClusterProfiler%204.0%3A%20a%20universal%20enrichment%20tool%20for%20interpreting%20omics%20data&amp;journal=Innovation%20%28Cambridge%20%28Mass%29%29&amp;volume=2&amp;issue=3&amp;publication_year=2021&amp;author=Wu%2CT&amp;author=Hu%2CE&amp;author=Xu%2CS&amp;author=Chen%2CM&amp;author=Guo%2CP&amp;author=Dai%2CZ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"27.\">\n<p class=\"c-article-references__text\" id=\"ref-CR27\">Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A. 2005;102(43):15545\u201350.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 27\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Gene%20set%20enrichment%20analysis%3A%20a%20knowledge-based%20approach%20for%20interpreting%20genome-wide%20expression%20profiles&amp;journal=Proc%20Natl%20Acad%20Sci%20U%20S%20A&amp;volume=102&amp;issue=43&amp;pages=15545-50&amp;publication_year=2005&amp;author=Subramanian%2CA&amp;author=Tamayo%2CP&amp;author=Mootha%2CVK&amp;author=Mukherjee%2CS&amp;author=Ebert%2CBL&amp;author=Gillette%2CMA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"28.\">\n<p class=\"c-article-references__text\" id=\"ref-CR28\">Aleksander SA, Balhoff J, Carbon S, Cherry JM, Drabkin HJ, Ebert D, et al. The Gene Ontology knowledgebase in 2023. Genetics. 2023. <a href=\"https:\/\/doi.org\/10.1093\/genetics\/iyad031\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1093\/genetics\/iyad031\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1093\/genetics\/iyad031<\/a>.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 28\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20Gene%20Ontology%20knowledgebase%20in%202023&amp;journal=Genetics&amp;doi=10.1093%2Fgenetics%2Fiyad031&amp;publication_year=2023&amp;author=Aleksander%2CSA&amp;author=Balhoff%2CJ&amp;author=Carbon%2CS&amp;author=Cherry%2CJM&amp;author=Drabkin%2CHJ&amp;author=Ebert%2CD\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"29.\">\n<p class=\"c-article-references__text\" id=\"ref-CR29\">Kanehisa M, Furumichi M, Sato Y, Matsuura Y, Ishiguro-Watanabe M. KEGG: biological systems database as a model of the real world. Nucleic Acids Res. 2025;53(D1):D672-d7.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 29\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=KEGG%3A%20biological%20systems%20database%20as%20a%20model%20of%20the%20real%20world&amp;journal=Nucleic%20Acids%20Res&amp;volume=53&amp;issue=D1&amp;pages=D672-d7&amp;publication_year=2025&amp;author=Kanehisa%2CM&amp;author=Furumichi%2CM&amp;author=Sato%2CY&amp;author=Matsuura%2CY&amp;author=Ishiguro-Watanabe%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"30.\">\n<p class=\"c-article-references__text\" id=\"ref-CR30\">Han Y, Wang Y, Dong X, Sun D, Liu Z, Yue J, et al. TISCH2: expanded datasets and new tools for single-cell transcriptome analyses of the tumor microenvironment. Nucleic Acids Res. 2023;51(D1):D1425-d31.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 30\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=TISCH2%3A%20expanded%20datasets%20and%20new%20tools%20for%20single-cell%20transcriptome%20analyses%20of%20the%20tumor%20microenvironment&amp;journal=Nucleic%20Acids%20Res&amp;volume=51&amp;issue=D1&amp;pages=D1425-d31&amp;publication_year=2023&amp;author=Han%2CY&amp;author=Wang%2CY&amp;author=Dong%2CX&amp;author=Sun%2CD&amp;author=Liu%2CZ&amp;author=Yue%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"31.\">\n<p class=\"c-article-references__text\" id=\"ref-CR31\">Yoshihara K, Shahmoradgoli M, Mart\u00ednez E, Vegesna R, Kim H, Torres-Garcia W, et al. Inferring tumour purity and stromal and immune cell admixture from expression data. Nat Commun. 2013;4:2612.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 31\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Inferring%20tumour%20purity%20and%20stromal%20and%20immune%20cell%20admixture%20from%20expression%20data&amp;journal=Nat%20Commun&amp;volume=4&amp;publication_year=2013&amp;author=Yoshihara%2CK&amp;author=Shahmoradgoli%2CM&amp;author=Mart%C3%ADnez%2CE&amp;author=Vegesna%2CR&amp;author=Kim%2CH&amp;author=Torres-Garcia%2CW\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"32.\">\n<p class=\"c-article-references__text\" id=\"ref-CR32\">Ru B, Wong CN, Tong Y, Zhong JY, Zhong SSW, Wu WC, et al. TISIDB: an integrated repository portal for tumor-immune system interactions. Bioinformatics. 2019;35(20):4200\u20132.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 32\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=TISIDB%3A%20an%20integrated%20repository%20portal%20for%20tumor-immune%20system%20interactions&amp;journal=Bioinformatics&amp;volume=35&amp;issue=20&amp;pages=4200-2&amp;publication_year=2019&amp;author=Ru%2CB&amp;author=Wong%2CCN&amp;author=Tong%2CY&amp;author=Zhong%2CJY&amp;author=Zhong%2CSSW&amp;author=Wu%2CWC\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"33.\">\n<p class=\"c-article-references__text\" id=\"ref-CR33\">Bonneville R, Krook MA, Kautto EA, Miya J, Wing MR, Chen HZ, et al. Landscape of microsatellite instability across 39 cancer types. JCO Precis Oncol. 2017. <a href=\"https:\/\/doi.org\/10.1200\/PO.17.00073\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1200\/PO.17.00073\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1200\/PO.17.00073<\/a>.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 33\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Landscape%20of%20microsatellite%20instability%20across%2039%20cancer%20types&amp;journal=JCO%20Precis%20Oncol&amp;doi=10.1200%2FPO.17.00073&amp;publication_year=2017&amp;author=Bonneville%2CR&amp;author=Krook%2CMA&amp;author=Kautto%2CEA&amp;author=Miya%2CJ&amp;author=Wing%2CMR&amp;author=Chen%2CHZ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"34.\">\n<p class=\"c-article-references__text\" id=\"ref-CR34\">Thorsson V, Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, et al. The immune landscape of cancer. Immunity. 2018;48(4):812\u2013e3014.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 34\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20immune%20landscape%20of%20cancer&amp;journal=Immunity&amp;volume=48&amp;issue=4&amp;pages=812-e3014&amp;publication_year=2018&amp;author=Thorsson%2CV&amp;author=Gibbs%2CDL&amp;author=Brown%2CSD&amp;author=Wolf%2CD&amp;author=Bortone%2CDS&amp;author=Ou%20Yang%2CTH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"35.\">\n<p class=\"c-article-references__text\" id=\"ref-CR35\">Fu J, Li K, Zhang W, Wan C, Zhang J, Jiang P, et al. Large-scale public data reuse to model immunotherapy response and resistance. Genome Med. 2020;12(1):21.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 35\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Large-scale%20public%20data%20reuse%20to%20model%20immunotherapy%20response%20and%20resistance&amp;journal=Genome%20Med&amp;volume=12&amp;issue=1&amp;publication_year=2020&amp;author=Fu%2CJ&amp;author=Li%2CK&amp;author=Zhang%2CW&amp;author=Wan%2CC&amp;author=Zhang%2CJ&amp;author=Jiang%2CP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"36.\">\n<p class=\"c-article-references__text\" id=\"ref-CR36\">Jiang P, Gu S, Pan D, Fu J, Sahu A, Hu X, et al. Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response. Nat Med. 2018;24(10):1550\u20138.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 36\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Signatures%20of%20T%20cell%20dysfunction%20and%20exclusion%20predict%20cancer%20immunotherapy%20response&amp;journal=Nat%20Med&amp;volume=24&amp;issue=10&amp;pages=1550-8&amp;publication_year=2018&amp;author=Jiang%2CP&amp;author=Gu%2CS&amp;author=Pan%2CD&amp;author=Fu%2CJ&amp;author=Sahu%2CA&amp;author=Hu%2CX\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"37.\">\n<p class=\"c-article-references__text\" id=\"ref-CR37\">Zeng Z, Wong CJ, Yang L, Ouardaoui N, Li D, Zhang W, et al. TISMO: syngeneic mouse tumor database to model tumor immunity and immunotherapy response. Nucleic Acids Res. 2022;50(D1):D1391-d7.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 37\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=TISMO%3A%20syngeneic%20mouse%20tumor%20database%20to%20model%20tumor%20immunity%20and%20immunotherapy%20response&amp;journal=Nucleic%20Acids%20Res&amp;volume=50&amp;issue=D1&amp;pages=D1391-d7&amp;publication_year=2022&amp;author=Zeng%2CZ&amp;author=Wong%2CCJ&amp;author=Yang%2CL&amp;author=Ouardaoui%2CN&amp;author=Li%2CD&amp;author=Zhang%2CW\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"38.\">\n<p class=\"c-article-references__text\" id=\"ref-CR38\">Davis AP, Wiegers TC, Johnson RJ, Sciaky D, Wiegers J, Mattingly CJ. Comparative toxicogenomics database (CTD): update 2023. Nucleic Acids Res. 2023;51(D1):D1257\u201362.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 38\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Comparative%20toxicogenomics%20database%20%28CTD%29%3A%20update%202023&amp;journal=Nucleic%20Acids%20Res&amp;volume=51&amp;issue=D1&amp;pages=D1257-62&amp;publication_year=2023&amp;author=Davis%2CAP&amp;author=Wiegers%2CTC&amp;author=Johnson%2CRJ&amp;author=Sciaky%2CD&amp;author=Wiegers%2CJ&amp;author=Mattingly%2CCJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"39.\">\n<p class=\"c-article-references__text\" id=\"ref-CR39\">Liu CJ, Hu FF, Xie GY, Miao YR, Li XW, Zeng Y, et al. GSCA: an integrated platform for gene set cancer analysis at genomic, pharmacogenomic and immunogenomic levels. Brief Bioinform. 2023. <a href=\"https:\/\/doi.org\/10.1093\/bib\/bbac558\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1093\/bib\/bbac558\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1093\/bib\/bbac558<\/a>.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 39\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=GSCA%3A%20an%20integrated%20platform%20for%20gene%20set%20cancer%20analysis%20at%20genomic%2C%20pharmacogenomic%20and%20immunogenomic%20levels&amp;journal=Brief%20Bioinform&amp;doi=10.1093%2Fbib%2Fbbac558&amp;publication_year=2023&amp;author=Liu%2CCJ&amp;author=Hu%2CFF&amp;author=Xie%2CGY&amp;author=Miao%2CYR&amp;author=Li%2CXW&amp;author=Zeng%2CY\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"40.\">\n<p class=\"c-article-references__text\" id=\"ref-CR40\">Xie H, Yang K, Qin C, Zhou X, Liu J, Nong J, et al. Sarcosine dehydrogenase as an immune infiltration-associated biomarker for the prognosis of hepatocellular carcinoma. J Cancer. 2024;15(1):149\u201365.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 40\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Sarcosine%20dehydrogenase%20as%20an%20immune%20infiltration-associated%20biomarker%20for%20the%20prognosis%20of%20hepatocellular%20carcinoma&amp;journal=J%20Cancer&amp;volume=15&amp;issue=1&amp;pages=149-65&amp;publication_year=2024&amp;author=Xie%2CH&amp;author=Yang%2CK&amp;author=Qin%2CC&amp;author=Zhou%2CX&amp;author=Liu%2CJ&amp;author=Nong%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"41.\">\n<p class=\"c-article-references__text\" id=\"ref-CR41\">Zongtao R, Xiaoyu Z, Jingya H. Expression and prognostic significance of Ferroptosis-related proteins SLC7A11 and GPX4 in renal cell carcinoma. Protein Pept Lett. 2023;30(10):868\u201376.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 41\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Expression%20and%20prognostic%20significance%20of%20Ferroptosis-related%20proteins%20SLC7A11%20and%20GPX4%20in%20renal%20cell%20carcinoma&amp;journal=Protein%20Pept%20Lett&amp;volume=30&amp;issue=10&amp;pages=868-76&amp;publication_year=2023&amp;author=Zongtao%2CR&amp;author=Xiaoyu%2CZ&amp;author=Jingya%2CH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"42.\">\n<p class=\"c-article-references__text\" id=\"ref-CR42\">Qin C, Qin H, Xie H, Li Y, Bi A, Liao X, et al. The role of MATN3 in cancer prognosis and immune infiltration across multiple tumor types. J Cancer. 2025;16(5):1519\u201337.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 42\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20role%20of%20MATN3%20in%20cancer%20prognosis%20and%20immune%20infiltration%20across%20multiple%20tumor%20types&amp;journal=J%20Cancer&amp;volume=16&amp;issue=5&amp;pages=1519-37&amp;publication_year=2025&amp;author=Qin%2CC&amp;author=Qin%2CH&amp;author=Xie%2CH&amp;author=Li%2CY&amp;author=Bi%2CA&amp;author=Liao%2CX\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"43.\">\n<p class=\"c-article-references__text\" id=\"ref-CR43\">Lei Z, Huan Y, Jing L, Ke W, Xiang C, Wei X, et al. Metabolomics-based approach to analyze the therapeutic targets and metabolites of a synovitis ointment for knee osteoarthritis. Curr Pharm Anal. 2023;19(3):222\u201334.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 43\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Metabolomics-based%20approach%20to%20analyze%20the%20therapeutic%20targets%20and%20metabolites%20of%20a%20synovitis%20ointment%20for%20knee%20osteoarthritis&amp;journal=Curr%20Pharm%20Anal&amp;volume=19&amp;issue=3&amp;pages=222-34&amp;publication_year=2023&amp;author=Lei%2CZ&amp;author=Huan%2CY&amp;author=Jing%2CL&amp;author=Ke%2CW&amp;author=Xiang%2CC&amp;author=Wei%2CX\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"44.\">\n<p class=\"c-article-references__text\" id=\"ref-CR44\">Zhou X, Li TM, Luo JZ, Lan CL, Wei ZL, Fu TH, et al. CYP2C8 suppress Proliferation, Migration, invasion and Sorafenib resistance of hepatocellular carcinoma via PI3K\/Akt\/p27(kip1) axis. J Hepatocell Carcinoma. 2021;8:1323\u201338.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 44\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=CYP2C8%20suppress%20Proliferation%2C%20Migration%2C%20invasion%20and%20Sorafenib%20resistance%20of%20hepatocellular%20carcinoma%20via%20PI3K%2FAkt%2Fp27%28kip1%29%20axis&amp;journal=J%20Hepatocell%20Carcinoma&amp;volume=8&amp;pages=1323-38&amp;publication_year=2021&amp;author=Zhou%2CX&amp;author=Li%2CTM&amp;author=Luo%2CJZ&amp;author=Lan%2CCL&amp;author=Wei%2CZL&amp;author=Fu%2CTH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"45.\">\n<p class=\"c-article-references__text\" id=\"ref-CR45\">Oerum S, Meynier V, Catala M, Tisn\u00e9 C. A comprehensive review of m6A\/m6Am RNA methyltransferase structures. Nucleic Acids Res. 2021;49(13):7239\u201355.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 45\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=A%20comprehensive%20review%20of%20m6A%2Fm6Am%20RNA%20methyltransferase%20structures&amp;journal=Nucleic%20Acids%20Res&amp;volume=49&amp;issue=13&amp;pages=7239-55&amp;publication_year=2021&amp;author=Oerum%2CS&amp;author=Meynier%2CV&amp;author=Catala%2CM&amp;author=Tisn%C3%A9%2CC\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"46.\">\n<p class=\"c-article-references__text\" id=\"ref-CR46\">Lee AV, Nestler KA, Chiappinelli KB. Therapeutic targeting of DNA methylation alterations in cancer. Pharmacol Ther. 2024;258:108640.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 46\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Therapeutic%20targeting%20of%20DNA%20methylation%20alterations%20in%20cancer&amp;journal=Pharmacol%20Ther&amp;volume=258&amp;publication_year=2024&amp;author=Lee%2CAV&amp;author=Nestler%2CKA&amp;author=Chiappinelli%2CKB\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"47.\">\n<p class=\"c-article-references__text\" id=\"ref-CR47\">Dagogo-Jack I, Shaw AT. Tumour heterogeneity and resistance to cancer therapies. Nat Rev Clin Oncol. 2018;15(2):81\u201394.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 47\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Tumour%20heterogeneity%20and%20resistance%20to%20cancer%20therapies&amp;journal=Nat%20Rev%20Clin%20Oncol&amp;volume=15&amp;issue=2&amp;pages=81-94&amp;publication_year=2018&amp;author=Dagogo-Jack%2CI&amp;author=Shaw%2CAT\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"48.\">\n<p class=\"c-article-references__text\" id=\"ref-CR48\">Cordani M, Dando I, Ambrosini G, Gonz\u00e1lez-Men\u00e9ndez P. Signaling, cancer cell plasticity, and intratumor heterogeneity. Cell Commun Signal. 2024;22(1):255.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 48\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Signaling%2C%20cancer%20cell%20plasticity%2C%20and%20intratumor%20heterogeneity&amp;journal=Cell%20Commun%20Signal&amp;volume=22&amp;issue=1&amp;publication_year=2024&amp;author=Cordani%2CM&amp;author=Dando%2CI&amp;author=Ambrosini%2CG&amp;author=Gonz%C3%A1lez-Men%C3%A9ndez%2CP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"49.\">\n<p class=\"c-article-references__text\" id=\"ref-CR49\">Loh JJ, Ma S. Hallmarks of cancer stemness. Cell Stem Cell. 2024;31(5):617\u201339.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 49\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Hallmarks%20of%20cancer%20stemness&amp;journal=Cell%20Stem%20Cell&amp;volume=31&amp;issue=5&amp;pages=617-39&amp;publication_year=2024&amp;author=Loh%2CJJ&amp;author=Ma%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"50.\">\n<p class=\"c-article-references__text\" id=\"ref-CR50\">Elhanani O, Ben-Uri R, Keren L. Spatial profiling technologies illuminate the tumor microenvironment. Cancer Cell. 2023;41(3):404\u201320.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 50\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Spatial%20profiling%20technologies%20illuminate%20the%20tumor%20microenvironment&amp;journal=Cancer%20Cell&amp;volume=41&amp;issue=3&amp;pages=404-20&amp;publication_year=2023&amp;author=Elhanani%2CO&amp;author=Ben-Uri%2CR&amp;author=Keren%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"51.\">\n<p class=\"c-article-references__text\" id=\"ref-CR51\">Gao X, Liu D-D, Liu J-Z, Wang R. TCGA-based analysis of oncogenic signaling pathways underlying oral squamous cell carcinoma. Oncol Transl Med. 2024;10(2):87\u201392.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 51\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=TCGA-based%20analysis%20of%20oncogenic%20signaling%20pathways%20underlying%20oral%20squamous%20cell%20carcinoma&amp;journal=Oncol%20Transl%20Med&amp;volume=10&amp;issue=2&amp;pages=87-92&amp;publication_year=2024&amp;author=Gao%2CX&amp;author=Liu%2CD-D&amp;author=Liu%2CJ-Z&amp;author=Wang%2CR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"52.\">\n<p class=\"c-article-references__text\" id=\"ref-CR52\">Wang Y, Wang J, Zeng T, Qi J. Data-mining-based biomarker evaluation and experimental validation of SHTN1 for bladder cancer. Cancer Genet. 2024;288\u2013289:43\u201353.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 52\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Data-mining-based%20biomarker%20evaluation%20and%20experimental%20validation%20of%20SHTN1%20for%20bladder%20cancer&amp;journal=Cancer%20Genet&amp;volume=288%E2%80%93289&amp;pages=43-53&amp;publication_year=2024&amp;author=Wang%2CY&amp;author=Wang%2CJ&amp;author=Zeng%2CT&amp;author=Qi%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"53.\">\n<p class=\"c-article-references__text\" id=\"ref-CR53\">Liu H, Guo Z, Wang P. Genetic expression in cancer research: challenges and complexity. Gene Rep. 2024;37:102042.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 53\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Genetic%20expression%20in%20cancer%20research%3A%20challenges%20and%20complexity&amp;journal=Gene%20Rep&amp;volume=37&amp;publication_year=2024&amp;author=Liu%2CH&amp;author=Guo%2CZ&amp;author=Wang%2CP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"54.\">\n<p class=\"c-article-references__text\" id=\"ref-CR54\">Liu H, Li Y, Karsidag M, Tu T, Wang P. Technical and biological biases in bulk transcriptomic data mining for cancer research. J Cancer. 2025;16(1):34\u201343.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 54\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Technical%20and%20biological%20biases%20in%20bulk%20transcriptomic%20data%20mining%20for%20cancer%20research&amp;journal=J%20Cancer&amp;volume=16&amp;issue=1&amp;pages=34-43&amp;publication_year=2025&amp;author=Liu%2CH&amp;author=Li%2CY&amp;author=Karsidag%2CM&amp;author=Tu%2CT&amp;author=Wang%2CP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"55.\">\n<p class=\"c-article-references__text\" id=\"ref-CR55\">Yao Z, Chen J, Wang Y, Cao L. Bioinformatics analysis and validation of HAUS6 as a key prognostic gene in squamous cell carcinoma of the tongue. Arch Oral Biol. 2024;164:106000.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 55\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Bioinformatics%20analysis%20and%20validation%20of%20HAUS6%20as%20a%20key%20prognostic%20gene%20in%20squamous%20cell%20carcinoma%20of%20the%20tongue&amp;journal=Arch%20Oral%20Biol&amp;volume=164&amp;publication_year=2024&amp;author=Yao%2CZ&amp;author=Chen%2CJ&amp;author=Wang%2CY&amp;author=Cao%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"56.\">\n<p class=\"c-article-references__text\" id=\"ref-CR56\">Kim H, Nguyen NP, Turner K, Wu S, Gujar AD, Luebeck J, et al. Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers. Nat Genet. 2020;52(9):891\u20137.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 56\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Extrachromosomal%20DNA%20is%20associated%20with%20oncogene%20amplification%20and%20poor%20outcome%20across%20multiple%20cancers&amp;journal=Nat%20Genet&amp;volume=52&amp;issue=9&amp;pages=891-7&amp;publication_year=2020&amp;author=Kim%2CH&amp;author=Nguyen%2CNP&amp;author=Turner%2CK&amp;author=Wu%2CS&amp;author=Gujar%2CAD&amp;author=Luebeck%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"57.\">\n<p class=\"c-article-references__text\" id=\"ref-CR57\">Shoshani O, Brunner SF, Yaeger R, Ly P, Nechemia-Arbely Y, Kim DH, et al. Chromothripsis drives the evolution of gene amplification in cancer. Nature. 2021;591(7848):137\u201341.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 57\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Chromothripsis%20drives%20the%20evolution%20of%20gene%20amplification%20in%20cancer&amp;journal=Nature&amp;volume=591&amp;issue=7848&amp;pages=137-41&amp;publication_year=2021&amp;author=Shoshani%2CO&amp;author=Brunner%2CSF&amp;author=Yaeger%2CR&amp;author=Ly%2CP&amp;author=Nechemia-Arbely%2CY&amp;author=Kim%2CDH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"58.\">\n<p class=\"c-article-references__text\" id=\"ref-CR58\">Lee JS. The mutational landscape of hepatocellular carcinoma. Clin Mol Hepatol. 2015;21(3):220\u20139.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 58\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20mutational%20landscape%20of%20hepatocellular%20carcinoma&amp;journal=Clin%20Mol%20Hepatol&amp;volume=21&amp;issue=3&amp;pages=220-9&amp;publication_year=2015&amp;author=Lee%2CJS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"59.\">\n<p class=\"c-article-references__text\" id=\"ref-CR59\">Yu J, Ling S, Hong J, Zhang L, Zhou W, Yin L, et al. TP53\/mTORC1-mediated bidirectional regulation of PD-L1 modulates immune evasion in hepatocellular carcinoma. J Immunother Cancer. 2023. <a href=\"https:\/\/doi.org\/10.1136\/jitc-2023-007479\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1136\/jitc-2023-007479\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1136\/jitc-2023-007479<\/a>.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 59\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=TP53%2FmTORC1-mediated%20bidirectional%20regulation%20of%20PD-L1%20modulates%20immune%20evasion%20in%20hepatocellular%20carcinoma&amp;journal=J%20Immunother%20Cancer&amp;doi=10.1136%2Fjitc-2023-007479&amp;publication_year=2023&amp;author=Yu%2CJ&amp;author=Ling%2CS&amp;author=Hong%2CJ&amp;author=Zhang%2CL&amp;author=Zhou%2CW&amp;author=Yin%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"60.\">\n<p class=\"c-article-references__text\" id=\"ref-CR60\">Nishiyama A, Nakanishi M. Navigating the DNA methylation landscape of cancer. Trends Genet. 2021;37(11):1012\u201327.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 60\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Navigating%20the%20DNA%20methylation%20landscape%20of%20cancer&amp;journal=Trends%20Genet&amp;volume=37&amp;issue=11&amp;pages=1012-27&amp;publication_year=2021&amp;author=Nishiyama%2CA&amp;author=Nakanishi%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"61.\">\n<p class=\"c-article-references__text\" id=\"ref-CR61\">Palmeri M, Mehnert J, Silk AW, Jabbour SK, Ganesan S, Popli P, et al. Real-world application of tumor mutational burden-high (TMB-high) and microsatellite instability (MSI) confirms their utility as immunotherapy biomarkers. ESMO Open. 2022;7(1):100336.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 61\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Real-world%20application%20of%20tumor%20mutational%20burden-high%20%28TMB-high%29%20and%20microsatellite%20instability%20%28MSI%29%20confirms%20their%20utility%20as%20immunotherapy%20biomarkers&amp;journal=ESMO%20Open&amp;volume=7&amp;issue=1&amp;publication_year=2022&amp;author=Palmeri%2CM&amp;author=Mehnert%2CJ&amp;author=Silk%2CAW&amp;author=Jabbour%2CSK&amp;author=Ganesan%2CS&amp;author=Popli%2CP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"62.\">\n<p class=\"c-article-references__text\" id=\"ref-CR62\">Zhu J, Zhang T, Li J, Lin J, Liang W, Huang W, et al. Association between tumor mutation burden (TMB) and outcomes of cancer patients treated with PD-1\/PD-L1 inhibitions: a meta-analysis. Front Pharmacol. 2019;10:673.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 62\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Association%20between%20tumor%20mutation%20burden%20%28TMB%29%20and%20outcomes%20of%20cancer%20patients%20treated%20with%20PD-1%2FPD-L1%20inhibitions%3A%20a%20meta-analysis&amp;journal=Front%20Pharmacol&amp;volume=10&amp;publication_year=2019&amp;author=Zhu%2CJ&amp;author=Zhang%2CT&amp;author=Li%2CJ&amp;author=Lin%2CJ&amp;author=Liang%2CW&amp;author=Huang%2CW\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"63.\">\n<p class=\"c-article-references__text\" id=\"ref-CR63\">Miranda A, Hamilton PT, Zhang AW, Pattnaik S, Becht E, Mezheyeuski A, et al. Cancer stemness, intratumoral heterogeneity, and immune response across cancers. Proc Natl Acad Sci U S A. 2019;116(18):9020\u20139.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 63\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Cancer%20stemness%2C%20intratumoral%20heterogeneity%2C%20and%20immune%20response%20across%20cancers&amp;journal=Proc%20Natl%20Acad%20Sci%20U%20S%20A&amp;volume=116&amp;issue=18&amp;pages=9020-9&amp;publication_year=2019&amp;author=Miranda%2CA&amp;author=Hamilton%2CPT&amp;author=Zhang%2CAW&amp;author=Pattnaik%2CS&amp;author=Becht%2CE&amp;author=Mezheyeuski%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"64.\">\n<p class=\"c-article-references__text\" id=\"ref-CR64\">Zhang Z, Wang ZX, Chen YX, Wu HX, Yin L, Zhao Q, et al. Integrated analysis of single-cell and bulk RNA sequencing data reveals a pan-cancer stemness signature predicting immunotherapy response. Genome Med. 2022;14(1):45.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 64\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Integrated%20analysis%20of%20single-cell%20and%20bulk%20RNA%20sequencing%20data%20reveals%20a%20pan-cancer%20stemness%20signature%20predicting%20immunotherapy%20response&amp;journal=Genome%20Med&amp;volume=14&amp;issue=1&amp;publication_year=2022&amp;author=Zhang%2CZ&amp;author=Wang%2CZX&amp;author=Chen%2CYX&amp;author=Wu%2CHX&amp;author=Yin%2CL&amp;author=Zhao%2CQ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"65.\">\n<p class=\"c-article-references__text\" id=\"ref-CR65\">Wu H, Geng Q, Shi W, Qiu C. Comprehensive pan-cancer analysis reveals CCDC58 as a carcinogenic factor related to immune infiltration. Apoptosis. 2024;29(3\u20134):536\u201355.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 65\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Comprehensive%20pan-cancer%20analysis%20reveals%20CCDC58%20as%20a%20carcinogenic%20factor%20related%20to%20immune%20infiltration&amp;journal=Apoptosis&amp;volume=29&amp;issue=3%E2%80%934&amp;pages=536-55&amp;publication_year=2024&amp;author=Wu%2CH&amp;author=Geng%2CQ&amp;author=Shi%2CW&amp;author=Qiu%2CC\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"66.\">\n<p class=\"c-article-references__text\" id=\"ref-CR66\">Wang Y, Xie Y, Qian L, Ding R, Pang R, Chen P, et al. RAB42 overexpression correlates with poor prognosis, immune cell infiltration and chemoresistance. Front Pharmacol. 2024;15:1445170.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 66\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=RAB42%20overexpression%20correlates%20with%20poor%20prognosis%2C%20immune%20cell%20infiltration%20and%20chemoresistance&amp;journal=Front%20Pharmacol&amp;volume=15&amp;publication_year=2024&amp;author=Wang%2CY&amp;author=Xie%2CY&amp;author=Qian%2CL&amp;author=Ding%2CR&amp;author=Pang%2CR&amp;author=Chen%2CP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"67.\">\n<p class=\"c-article-references__text\" id=\"ref-CR67\">Xu X, Xu Y, Hu W, Hong W, Wang Y, Zhang X, et al. Stromal score is a promising index in tumor patients\u2019 outcome determination. Heliyon. 2023;9(11):e22432.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 67\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Stromal%20score%20is%20a%20promising%20index%20in%20tumor%20patients%E2%80%99%20outcome%20determination&amp;journal=Heliyon&amp;volume=9&amp;issue=11&amp;publication_year=2023&amp;author=Xu%2CX&amp;author=Xu%2CY&amp;author=Hu%2CW&amp;author=Hong%2CW&amp;author=Wang%2CY&amp;author=Zhang%2CX\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"68.\">\n<p class=\"c-article-references__text\" id=\"ref-CR68\">Wu Y, Ma J, Yang X, Nan F, Zhang T, Ji S, et al. Neutrophil profiling illuminates anti-tumor antigen-presenting potency. Cell. 2024;187(6):1422\u2013e3924.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 68\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Neutrophil%20profiling%20illuminates%20anti-tumor%20antigen-presenting%20potency&amp;journal=Cell&amp;volume=187&amp;issue=6&amp;pages=1422-e3924&amp;publication_year=2024&amp;author=Wu%2CY&amp;author=Ma%2CJ&amp;author=Yang%2CX&amp;author=Nan%2CF&amp;author=Zhang%2CT&amp;author=Ji%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"69.\">\n<p class=\"c-article-references__text\" id=\"ref-CR69\">Cha JH, Chan LC, Li CW, Hsu JL, Hung MC. Mechanisms controlling PD-L1 expression in cancer. Mol Cell. 2019;76(3):359\u201370.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 69\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Mechanisms%20controlling%20PD-L1%20expression%20in%20cancer&amp;journal=Mol%20Cell&amp;volume=76&amp;issue=3&amp;pages=359-70&amp;publication_year=2019&amp;author=Cha%2CJH&amp;author=Chan%2CLC&amp;author=Li%2CCW&amp;author=Hsu%2CJL&amp;author=Hung%2CMC\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"70.\">\n<p class=\"c-article-references__text\" id=\"ref-CR70\">Francisco LM, Sage PT, Sharpe AH. The PD-1 pathway in tolerance and autoimmunity. Immunol Rev. 2010;236:219\u201342.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 70\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20PD-1%20pathway%20in%20tolerance%20and%20autoimmunity&amp;journal=Immunol%20Rev&amp;volume=236&amp;pages=219-42&amp;publication_year=2010&amp;author=Francisco%2CLM&amp;author=Sage%2CPT&amp;author=Sharpe%2CAH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"71.\">\n<p class=\"c-article-references__text\" id=\"ref-CR71\">Lin X, Kang K, Chen P, Zeng Z, Li G, Xiong W, et al. Regulatory mechanisms of PD-1\/PD-L1 in cancers. Mol Cancer. 2024;23(1):108.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 71\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Regulatory%20mechanisms%20of%20PD-1%2FPD-L1%20in%20cancers&amp;journal=Mol%20Cancer&amp;volume=23&amp;issue=1&amp;publication_year=2024&amp;author=Lin%2CX&amp;author=Kang%2CK&amp;author=Chen%2CP&amp;author=Zeng%2CZ&amp;author=Li%2CG&amp;author=Xiong%2CW\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n<li class=\"c-article-references__item js-c-reading-companion-references-item\" data-counter=\"72.\">\n<p class=\"c-article-references__text\" id=\"ref-CR72\">Liu H, Yang Z. Time management and personal efficiency in the age of computational and systems oncology. Comput Syst Oncol. 2024;4(1):e70001.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 72\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Time%20management%20and%20personal%20efficiency%20in%20the%20age%20of%20computational%20and%20systems%20oncology&amp;journal=Comput%20Syst%20Oncol&amp;volume=4&amp;issue=1&amp;publication_year=2024&amp;author=Liu%2CH&amp;author=Yang%2CZ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<\/li>\n","protected":false},"excerpt":{"rendered":"Burden of disease scenarios. For 204 countries and territories, 2022\u20132050: a forecasting analysis for the global burden of&hellip;\n","protected":false},"author":2,"featured_media":198415,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[78],"tags":[2566,7580,18,109989,109991,135,19,109993,17,109990,109992],"class_list":{"0":"post-198414","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health","8":"tag-cancer-research","9":"tag-cell-biology","10":"tag-eire","11":"tag-haus6","12":"tag-hcc","13":"tag-health","14":"tag-ie","15":"tag-immune-analysis","16":"tag-ireland","17":"tag-pan-cancer","18":"tag-prognosis-prediction"},"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@ie\/115607332622772768","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/posts\/198414","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/comments?post=198414"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/posts\/198414\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/media\/198415"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/media?parent=198414"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/categories?post=198414"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/tags?post=198414"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}