{"id":29230,"date":"2025-08-28T19:01:07","date_gmt":"2025-08-28T19:01:07","guid":{"rendered":"https:\/\/www.europesays.com\/ie\/29230\/"},"modified":"2025-08-28T19:01:07","modified_gmt":"2025-08-28T19:01:07","slug":"super-common-otc-meds-fueling-antibiotic-resistance-study","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/ie\/29230\/","title":{"rendered":"Super common OTC meds fueling antibiotic resistance: study"},"content":{"rendered":"<p>Welcome to Club Meds.<\/p>\n<p>More than 4 out of 10 senior citizens take five or more prescription medications \u2014 <a href=\"https:\/\/nypost.com\/2023\/10\/13\/americans-will-spend-half-their-lives-taking-prescription-drugs-penn-state-study\/\" rel=\"nofollow noopener\" target=\"_blank\">a phenomenon<\/a> known as polypharmacy, <a href=\"https:\/\/jamanetwork.com\/journals\/jama\/article-abstract\/2821721\" target=\"_blank\" rel=\"noopener nofollow\">research shows<\/a>.<\/p>\n<p>This practice increases the risk of addiction and medication errors, like taking the wrong dosage or skipping doses altogether. Potential consequences include hospitalization, <a href=\"https:\/\/nypost.com\/2020\/03\/03\/medication-fog-can-mimic-or-worsen-dementia-in-the-elderly\/\" rel=\"nofollow noopener\" target=\"_blank\">mental impairment<\/a> and painful falls.<\/p>\n<p>Many seniors take several pills a day, a practice known as polypharmacy. Pixel-Shot \u2013 stock.adobe.com<\/p>\n<p><a href=\"https:\/\/unisa.edu.au\/media-centre\/Releases\/2025\/common-painkillers-linked-to-antibiotic-resistance\/\" target=\"_blank\" rel=\"noopener nofollow\">A new report<\/a> warns of another possible result \u2014 bacterial infections that are more difficult to treat.<\/p>\n<p>A team from the University of South Australia tested nine medications common in nursing homes, finding that two common painkillers help bacteria become more resistant to antibiotics \u2014 especially when taken together.<\/p>\n<p>\u201cAntibiotics have long been vital in treating infectious diseases, but their widespread overuse and misuse have driven a global rise in <a href=\"https:\/\/nypost.com\/2024\/09\/18\/us-news\/superbug-crisis-will-likely-kill-millions-by-2050-study-finds\/\" rel=\"nofollow noopener\" target=\"_blank\">antibiotic-resistant bacteria<\/a>,\u201d said Rietie Venter, an associate professor at UniSA and lead researcher on the study.<\/p>\n<p>\u201cThis is especially prevalent in residential aged care facilities, where older people are more likely to be prescribed multiple medications \u2014 not just antibiotics, but also drugs for pain, sleep or blood pressure \u2014 making it an ideal breeding ground for gut bacteria to become resistant to antibiotics.\u201d<\/p>\n<p>Bacteria resistant to antibiotics make previously curable infections tricky or impossible to treat. nobeastsofierce \u2013 stock.adobe.com<\/p>\n<p>Antibiotic-resistant infections contribute to <a href=\"https:\/\/www.who.int\/news\/item\/28-07-2023-vaccines-could-avert-half-a-million-deaths-associated-with-anti-microbial-resistance-a-year\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">an estimated 4.95 million deaths<\/a> worldwide each year.<\/p>\n<p>Venter\u2019s team assessed the over-the-counter painkillers ibuprofen and acetaminophen, the anti-inflammatory diclofenac, the diuretic furosemide, the diabetes drug <a href=\"https:\/\/nypost.com\/2023\/07\/31\/diabetes-drug-metformin-helps-seniors-fight-zombie-cells-new-study\/\" rel=\"nofollow noopener\" target=\"_blank\">metformin<\/a>, the statin atorvastatin, the opioid tramadol, the sedative temazepam and the decongestant pseudoephedrine.<\/p>\n<p>The researchers explored what happens when bacteria are exposed to these non-antibiotics and the antibiotic ciprofloxacin \u2014 a powerful drug used to treat bacterial infections in the respiratory, urinary and gastrointestinal tracts as well as other areas of the body.<\/p>\n<p>They found that the E. coli developed more genetic mutations that promote faster growth and antibiotic resistance when exposed to ciprofloxacin, ibuprofen and acetaminophen than when exposed to just ciprofloxacin.<\/p>\n<p>\u201cWorryingly, the bacteria were not only resistant to the antibiotic ciprofloxacin, but increased resistance was also observed to multiple other antibiotics from different classes,\u201d Venter said.<\/p>\n<p>A team from the University of South Australia found that ibuprofen (seen here) and acetaminophen help bacteria become more resistant to antibiotics \u2014 especially when taken together. Michelle \u2013 stock.adobe.com<\/p>\n<p>\u201cWe also uncovered the genetic mechanisms behind this resistance,\u201d she added, \u201cwith ibuprofen and [acetaminophen] both activating the bacteria\u2019s defenses to expel antibiotics and render them less effective.\u201d<\/p>\n<p>Ibuprofen (brand names: Advil and Motrin) and acetaminophen (Tylenol) are extremely popular because they are designed to reduce fever, aches and minor pains. <\/p>\n<p>Venter is not discouraging their use but is recommending consumers \u201cbe more mindful about how they interact with antibiotics.\u201d<\/p>\n<p>\u201cAntibiotic resistance isn\u2019t just about antibiotics anymore,\u201d she said.<\/p>\n<p>\u201cThis study is a clear reminder that we need to carefully consider the risks of using multiple medications \u2014 particularly in aged care, where residents are often prescribed a mix of long-term treatments.\u201d<\/p>\n<p>The findings were published this week in the journal <a href=\"https:\/\/www.nature.com\/articles\/s44259-025-00144-w\" target=\"_blank\" rel=\"noopener nofollow\">Antimicrobials and Resistance<\/a>.<\/p>\n<p>The researchers are calling for additional studies on how drug interactions can reduce antibiotic effectiveness.<\/p>\n","protected":false},"excerpt":{"rendered":"Welcome to Club Meds. More than 4 out of 10 senior citizens take five or more prescription medications&hellip;\n","protected":false},"author":2,"featured_media":29231,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[274],"tags":[1669,19746,18,135,19,23309,17,462,96,464,172,133,8853,14176],"class_list":{"0":"post-29230","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-medication","8":"tag-bacteria","9":"tag-e-coli","10":"tag-eire","11":"tag-health","12":"tag-ie","13":"tag-infections","14":"tag-ireland","15":"tag-medication","16":"tag-medicine","17":"tag-prescription-drugs","18":"tag-research","19":"tag-science","20":"tag-senior-citizens","21":"tag-study-says"},"share_on_mastodon":{"url":"","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/posts\/29230","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/comments?post=29230"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/posts\/29230\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/media\/29231"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/media?parent=29230"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/categories?post=29230"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/tags?post=29230"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}