{"id":483134,"date":"2026-05-13T20:11:11","date_gmt":"2026-05-13T20:11:11","guid":{"rendered":"https:\/\/www.europesays.com\/ie\/483134\/"},"modified":"2026-05-13T20:11:11","modified_gmt":"2026-05-13T20:11:11","slug":"allepre-nurse-coordinated-prevention-program-may-reduce-long-term-cv-risk","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/ie\/483134\/","title":{"rendered":"ALLEPRE: Nurse-Coordinated Prevention Program May Reduce Long-Term CV Risk"},"content":{"rendered":"<p>Implementing a nurse-coordinated prevention program (NCPP) significantly reduced long-term major adverse cardiovascular events (MACE) and improved body weight control, physical activity and pharmacotherapy adherence in post-hospitalization patients with acute coronary syndrome (ACS), according to <a rel=\"noopener noreferrer nofollow\" href=\"https:\/\/academic.oup.com\/eurheartj\/advance-article-abstract\/doi\/10.1093\/eurheartj\/ehag255\/8669769?redirectedFrom=fulltext\" target=\"_blank\">results from the ALLEPRE trial<\/a> published May 5 in EHJ.<\/p>\n<p>This multicenter cohort study evaluated 2,057 patients (mean age of 64 years, 22% women) with ACS across seven centers in Italy from October 2012 through March 2022. Patients were randomized to either the NCPP group (n=1,031) or the standard of care (SOC) group (n=1,026).<\/p>\n<p>Patients in the NCPP group attended nine individual educational sessions over four years, where centrally trained nurses who were already involved in ACS follow-up assessed cardiovascular risk profiles, encouraged medication adherence and healthier lifestyles, as well as made multidisciplinary team referrals. Patients in the SOC group followed the standard practices of their respective hospitals.<\/p>\n<p><strong>Giulia Magnani, MD<\/strong>, et al., defined the primary MACE endpoint as the composite of cardiovascular death, nonfatal myocardial infarction (MI) and nonfatal stroke. Secondary endpoints were defined as the primary endpoint plus myocardial ischemia-driven revascularization (IDR), all-cause death, all recurrent primary endpoint events or heart failure hospitalization.<\/p>\n<p>At the six-year follow-up, the rate of MACE was 30% lower in the NCPP group than the SOC group (16% vs. 22%, respectively; hazard ratio [HR], 0.70, p&lt;0.0001), a finding mainly driven by the reduction in nonfatal MI (9% vs. 15%; HR, 0.60; p=0.0001).<\/p>\n<p>Additionally, there was a 23% reduction in the secondary outcome of MACE plus IDR (HR, 0.77; p=0.0005). Body weight, physical activity and medication pharmacotherapy adherence were all significantly improved with the NCPP strategy vs. SOC strategy.<\/p>\n<p>\u201cThe results of this trial are particularly relevant as an increasing number of ACS patients are living longer, and there is a growing need for innovative, [patient-centered] models that can counteract the fragmentation of [health care] services,\u201d write the authors. \u201c\u2026including an NCPP in [health care] provision may help the successful implementation of secondary prevention strategies and guarantee clinical efficacy.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"Implementing a nurse-coordinated prevention program (NCPP) significantly reduced long-term major adverse cardiovascular events (MACE) and improved body weight&hellip;\n","protected":false},"author":2,"featured_media":101504,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[74],"tags":[18,19,17,82],"class_list":{"0":"post-483134","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-technology","8":"tag-eire","9":"tag-ie","10":"tag-ireland","11":"tag-technology"},"share_on_mastodon":{"url":"","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/posts\/483134","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/comments?post=483134"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/posts\/483134\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/media\/101504"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/media?parent=483134"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/categories?post=483134"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/ie\/wp-json\/wp\/v2\/tags?post=483134"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}