{"id":8254,"date":"2026-04-20T04:00:14","date_gmt":"2026-04-20T04:00:14","guid":{"rendered":"https:\/\/www.europesays.com\/japan\/8254\/"},"modified":"2026-04-20T04:00:14","modified_gmt":"2026-04-20T04:00:14","slug":"guidelines-for-the-appropriate-use-of-renal-denervation-systems-in-japan-endorsed-by-the-japanese-society-of-hypertension-jsh-the-japanese-association-of-cardiovascular-intervention-and-therapeuti","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/japan\/8254\/","title":{"rendered":"Guidelines for the appropriate use of renal denervation systems in Japan: endorsed by the Japanese Society of Hypertension (JSH), the Japanese Association of Cardiovascular Intervention and Therapeutics (CVIT), and the Japanese Circulation Society (JCS), and their positioning in the JSH 2025 guidelines"},"content":{"rendered":"

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Kario K, Hettrick DA, Prejbisz A, Januszewicz A. Obstructive Sleep Apnea-Induced Neurogenic Nocturnal Hypertension: A Potential Role of Renal Denervation?. Hypertension. 2021;77:1047\u201360.<\/p>\n

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Kario K, Pickering TG, Umeda Y, Hoshide S, Hoshide Y, Morinari M, et al. Morning surge in blood pressure as a predictor of silent and clinical cerebrovascular disease in elderly hypertensives: a prospective study. Circulation. 2003;107:1401\u20136.<\/p>\n

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Hoshide S, Kario K. Morning surge in blood pressure and stroke events in a large modern ambulatory blood pressure monitoring cohort: Results of the JAMP Study. Hypertension. 2021;78:894\u20136.<\/p>\n

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Kario K. Proposal of a new strategy for ambulatory blood pressure profile-based management of resistant hypertension in the era of renal denervation. Hypertens Res. 2013;36:478\u201384.<\/p>\n

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Kario K, Bhatt DL, Brar S, Cohen SA, Fahy M, Bakris GL. Effect of Catheter-Based Renal Denervation on Morning and Nocturnal Blood Pressure: Insights From SYMPLICITY HTN-3 and SYMPLICITY HTN-Japan. Hypertension. 2015;66:1130\u20137.<\/p>\n

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Kario K, Bhatt DL, Kandzari DE, Brar S, Flack JM, Gilbert C, et al. Impact of Renal Denervation on Patients With Obstructive Sleep Apnea and Resistant Hypertension\u3000- Insights From the SYMPLICITY HTN-3 Trial. Circ J. 2016;80:1404\u201312.<\/p>\n

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Kario K, Weber MA, Mahfoud F, Kandzari DE, Schmieder RE, Kirtane AJ, et al. Changes in 24-Hour Patterns of Blood Pressure in Hypertension Following Renal Denervation Therapy. Hypertensiong. 2019;74:244\u20139.<\/p>\n

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Kario K, Kim BK, Aoki J, Wong AY, Lee YH, Wongpraparut N, et al. Renal Denervation in Asia: Consensus Statement of the Asia Renal Denervation Consortium. Hypertension. 2020;75:590\u2013602.<\/p>\n

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Kario K, Weber MA, B\u00f6hm M, Townsend RR, Mahfoud F, Schmieder RE, et al. Effect of renal denervation in attenuating the stress of morning surge in blood pressure: post-hoc analysis from the SPYRAL HTN-ON MED trial. Clin Res Cardiol. 2021;110:725\u201331.<\/p>\n

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Lauder L, Mahfoud F, Azizi M, Bhatt DL, Ewen S, Kario K, et al. Hypertension management in patients with cardiovascular comorbidities. Eur Heart J. 2023;44:2066\u201377.<\/p>\n

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Kario K. Essential manual of perfect 24-hour blood pressure management from morning to nocturnal hypertension (2nd edition). Pp1-374, London, Wiley, 2022.<\/p>\n

Kario K, Kagitani H, Hayashi S, Hanamura S, Ozawa K, Kanegae H. A Japan nationwide web-based survey of patient preference for renal denervation for hypertension treatment. Hypertens Res. 2022;45:232\u201340.<\/p>\n

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Schmieder RE, H\u00f6gerl K, Jung S, Bramlage P, Veelken R, Ott C. Patient preference for therapies in hypertension: a cross-sectional survey of German patients. Clin Res Cardiol. 2019;108:1331\u201342.<\/p>\n

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Kario K, Cao KN, Tanaka Y, Ryschon AM, Pietzsch JB. Cost-effectiveness of radiofrequency renal denervation for uncontrolled hypertension in Japan. J Clin Hypertens (Greenwich). 2024;26:1502\u201312.<\/p>\n

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Sharp ASP, Cao KN, Esler MD, Kandzari DE, Lobo MD, Schmieder RE, et al. Cost-effectiveness of catheter-based radiofrequency renal denervation for the treatment of uncontrolled hypertension: an analysis for the UK based on recent clinical evidence. Eur Heart J Qual Care Clin Outcomes. 2024;10:698\u2013708.<\/p>\n

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Kario K. Implementation hypertension: a new paradigm for global hypertension control in the JSH 2025, WHO 2025, and AHA\/ACC 2025 guideline era. Hypertens Res. 2026;49:1-6.<\/p>\n

Kario K. Achievement rate of blood pressure control <130\/80 mmHg as the core metric of implementation hypertension, based on the new JSH2025 and AHA\/ACC2025 guidelines. Hypertens Res. 2025;48:2784\u20138.<\/p>\n

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Kario K, Nishiyama A, Shibata S, Arima H, Furuhashi M, Ichihara A, et al. Digital hypertension, implementation hypertension, and internationalization – 3 pillars of Japanese Society of Hypertension 2024-2026 advancing hypertension science from Japan to the world in the information network era. Hypertens Res. 2025;48:1\u20135.<\/p>\n

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