Espectro clínico da paralisia supranuclear progressiva: relato de caso

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Como Citar:
RORATTO, Danilo Henrique; MASCARENHAS, Tainá de Sousa. Espectro clínico da paralisia supranuclear progressiva: relato de caso. Revista Sociedade Científica, vol. 9, n. 1, p. 993-999, 2026.
https://doi.org/10.61411/rsc2026131819
DOI: 10.61411/rsc2026131819
Área do conhecimento: Ciências da Saúde
Sub-área: Medicina; Neurologia
Palavras-chaves: Progressive Supranuclear Palsy; Richardson Syndrome; Postural Instability; Ophthalmoplegia; Case Report.
Publicado: 24 de abril de 2026.

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Abstract

Progressive supranuclear palsy (PSP) is a rare primary tauopathy within the spectrum of atypical parkinsonian syndromes, often underdiagnosed due to its clinical heterogeneity. This study aims to report a case of PSP, highlighting its clinical features, disease progression, and diagnostic challenges. We describe a 67-year-old institutionalized male patient, longitudinally followed in a long-term care facility, whose initial presentation consisted of recurrent unexplained falls, progressing to rapid postural instability and functional decline. During follow-up, the patient developed predominantly axial parkinsonism, poor sustained response to levodopa, frontal behavioral changes, and progressive cognitive impairment, in addition to dysarthria and dysphagia. Subsequently, vertical supranuclear ophthalmoparesis with preserved vestibulo-ocular reflex was observed. Neuroimaging studies revealed only nonspecific findings, without structural abnormalities explaining the clinical picture. The overall findings were consistent with PSP, emphasizing the importance of early recognition of cardinal features – particularly early falls and oculomotor abnormalities – and the diagnostic challenges due to overlap with other parkinsonian syndromes.

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