Pesquisa da USP desenvolve ‘vacina inteligente’ contra a chikungunya; entenda – Noticias R7

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\n
• Pesquisadores da USP desenvolveram uma \”vacina inteligente\” contra a chikungunya usando engenharia genética no vírus.

\n

• O estudo, realizado em parceria com pesquisadores alemães, mostrou eficácia em camundongos com apenas uma dose.

\n

• A nova vacina combina os benefícios das vacinas atenuadas e inativadas, sendo potencialmente mais segura e abrangente.

\n

• A tecnologia pode ser aplicada na produção de vacinas para outras doenças, como zika, dengue, febre amarela e SARS-CoV.

\n

\n

Produzido pela Ri7a – a Inteligência Artificial do R7

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“,”streams”:[{“provider”:”mediaconvert”,”width”:640,”stream_type”:”ts”,”bitrate”:580,”filesize”:105702248,”url”:”https://d147dt0faszygd.cloudfront.net/wp-newr7/20260819/6a8612483c1b690c95465eaf/t_0f59cbc061444b109ff48dfc39e8cfaf_name_5352623_ERP_RRN_1908_VACINA/mobile.m3u8″,”height”:360},{“provider”:”mediaconvert”,”width”:854,”stream_type”:”ts”,”bitrate”:910,”filesize”:149771328,”url”:”https://d147dt0faszygd.cloudfront.net/wp-newr7/20260819/6a8612483c1b690c95465eaf/t_0f59cbc061444b109ff48dfc39e8cfaf_name_5352623_ERP_RRN_1908_VACINA/mobile.m3u8″,”height”:480},{“provider”:”mediaconvert”,”width”:960,”stream_type”:”ts”,”bitrate”:1600,”filesize”:242654608,”url”:”https://d147dt0faszygd.cloudfront.net/wp-newr7/20260819/6a8612483c1b690c95465eaf/t_0f59cbc061444b109ff48dfc39e8cfaf_name_5352623_ERP_RRN_1908_VACINA/sd.m3u8″,”height”:540},{“provider”:”mediaconvert”,”width”:1280,”stream_type”:”ts”,”bitrate”:3000,”filesize”:430707060,”url”:”https://d147dt0faszygd.cloudfront.net/wp-newr7/20260819/6a8612483c1b690c95465eaf/t_0f59cbc061444b109ff48dfc39e8cfaf_name_5352623_ERP_RRN_1908_VACINA/hd.m3u8″,”height”:720},{“provider”:”mediaconvert”,”width”:960,”stream_type”:”mp4″,”bitrate”:1600,”filesize”:228032315,”url”:”https://d147dt0faszygd.cloudfront.net/wp-newr7/20260819/6a8612483c1b690c95465eaf/t_0f59cbc061444b109ff48dfc39e8cfaf_name_5352623_ERP_RRN_1908_VACINA/file_960x540-1600-v4.mp4″,”height”:540}],”canonical_url”:”/record-news/link-record-news/video/novo-imunizante-contra-chikungunya-usa-virus-geneticamente-modificado-19082026/”,”promo_items”:{“basic”:{“credits”:{},”width”:960,”type”:”image”,”version”:”0.5.8″,”url”:”https://d22yf0mxeu0gma.cloudfront.net/08-19-2026/t_57c07c29f67b4e6594f84384245b3961_name_file_960x540_1600_v4_.jpg”,”height”:540,”auth”:{“1″:”c29bb0e4fa938cbb6f781c70dedcf075270db633747a6f3aa4cf85f49ac1634f”}}},”version”:”0.8.0″,”distributor”:{“category”:”staff”},”canonical_website”:”noticias”,”revision”:{“published”:true},”video_type”:”clip”,”planning”:{“scheduling”:{}},”powaConfig”:{“sampleRate”:1},”display_date”:”2026-08-19T21:48:41Z”,”headlines”:{“meta_title”:”vacina inteligente chikungunya usp”,”basic”:”Novo imunizante contra chikungunya usa vírus geneticamente modificado”},”websites”:{“noticias”:{“website_url”:”/record-news/link-record-news/video/novo-imunizante-contra-chikungunya-usa-virus-geneticamente-modificado-19082026/”,”website_section”:{“path”:”/record-news/link-record-news”,”_website”:”noticias”,”name”:”Link Record News”,”_id”:”/record-news/link-record-news”,”type”:”section”,”version”:”0.6.0″,”primary”:true}},”r7″:{“website_url”:”/todos-os-videos/video/novo-imunizante-contra-chikungunya-usa-virus-geneticamente-modificado-19082026/”,”website_section”:{“path”:”/todos-os-videos”,”_website”:”r7″,”name”:”Todos os Vídeos”,”_id”:”/todos-os-videos”,”type”:”section”,”version”:”0.6.0″,”primary”:true}}},”_id”:”c807ef28-1e44-443a-909c-0dcb364933f8″,”created_date”:”2026-08-19T20:30:00Z”,”publish_date”:”2026-08-19T21:48:41Z”},{“_id”:”A5FKQEM5UVCQJAYLLKG2CMPIJA”,”additional_properties”:{},”type”:”text”,”content”:”Uma nova pesquisa da USP pode mudar a lógica da produção de vacinas. Em parceria com colaboradores alemães, pesquisadores da Universidade de São Paulo desenvolveram um “imunizante inteligente” a partir de uma versão geneticamente modificada do vírus chikungunya.”},{“_id”:”5N7OI4ITHVEQNLIJT4TC2YLIS4″,”additional_properties”:{},”type”:”text”,”content”:”O estudo, publicado em uma revista científica internacional, fez testes em camundongos e teve eficácia com apenas uma dose da formulação. Em entrevista ao Link News, o primeiro autor da pesquisa, Danillo Espósito, conta que a pesquisa buscava desenvolver uma vacina mais segura contra a doença.”},{“subtype”:”formatted_image”,”_id”:”GRTATVA63BE7JCILKJBLSN757M”,”embed”:{“id”:”custom_powerup_1787174549839″,”config”:{“imageFormat”:”small”,”imageId”:”H53XAYWQFNHRDIN4KESQQ4WTYU”,”creditIPTC”:”Reprodução/Record News”,”caption”:”Processo envolveu uma engenharia genética do vírus”},”url”:”/”},”type”:”custom_embed”},{“_id”:”UAUGZNPL6FCMRC7TQC2JWTC3XA”,”additional_properties”:{},”type”:”text”,”content”:”“A vacina que a gente tem de chikungunya licenciada é atenuada […]. Só que essas vacinas têm restrições, principalmente de idade”, diz o pesquisador. Ele explica que o imunizante utilizado atualmente no Brasil é indicado para pessoas entre 18 e 59 anos, sem comorbidades. “O que a gente quis desenvolver no laboratório foi uma vacina que combinasse os benefícios dos dois tipos de vacina, da vacina que é atenuada e de uma vacina inativada.””},{“_id”:”AQTBZJ5FRZHKTDKMA7BHMBVUEY”,”additional_properties”:{},”type”:”text”,”content”:”Para isso foi preciso realizar uma engenharia genética no vírus. Segundo Espósito, a ideia é bem simples. “Quando a gente utiliza essa vacina, o vírus vai entrar uma vez na célula, ele vai produzir todas as suas proteínas, vai fazer todo o ciclo de replicação, só que tudo que é produzido a partir disso vai servir somente como proteínas para o sistema imunológico fazer anticorpos para proteger a gente contra a chikungunya”, diz.”},{“_id”:”DDTPEHW54VDRXCAXQ5EF4D5VOA”,”additional_properties”:{},”type”:”text”,”content”:”O pesquisador destaca que a tecnologia pode ser utilizada na produção de vacinas para outras doenças. “O vírus, para ser infeccioso, precisa passar por um processo que vai deixá-lo maduro, e a gente atua em cima desse processo, então, no ciclo dele, ele não vai passar por esse processo de maturação. E os vírus que têm esse ciclo, uma parte do ciclo parecido com o chikungunya, como zika, dengue, febre amarela e outros vírus também, como sars-cov, a gente pode atuar no mesmo processo e fazer com que esse vírus fique inativado após a replicação dele.””},{“_id”:”SBWXEAAJZNCIVNYJYZO55OR3UI”,”type”:”raw_html”,”content”:”\n\n

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