{"id":440749,"date":"2026-07-05T15:04:23","date_gmt":"2026-07-05T15:04:23","guid":{"rendered":"https:\/\/www.europesays.com\/pt\/440749\/"},"modified":"2026-07-05T15:04:23","modified_gmt":"2026-07-05T15:04:23","slug":"transicao-proteica-na-modulacao-metabolica-integrativa-implicacoes-no-eixo-metionina-homocisteina-bioenergetica-gastrica-e-permeabilidade-intestinal","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/pt\/440749\/","title":{"rendered":"Transi\u00e7\u00e3o proteica na modula\u00e7\u00e3o metab\u00f3lica integrativa: implica\u00e7\u00f5es no eixo metionina-homociste\u00edna, bioenerg\u00e9tica g\u00e1strica e permeabilidade intestinal"},"content":{"rendered":"

\nTransi\u00e7\u00e3o proteica na modula\u00e7\u00e3o metab\u00f3lica integrativa: implica\u00e7\u00f5es no eixo metionina-homociste\u00edna, bioenerg\u00e9tica g\u00e1strica e permeabilidade intestinal<\/strong><\/p>\n

Lilian de Cassia Delgatto<\/b> <\/p>\n

.<\/p>\n

Como Citar:<\/b>
DELGATTO, Lilian de Cassia. Transi\u00e7\u00e3o proteica na modula\u00e7\u00e3o metab\u00f3lica integrativa: implica\u00e7\u00f5es no eixo metionina-homociste\u00edna, bioenerg\u00e9tica g\u00e1strica e permeabilidade intestinal. Revista Sociedade Cient\u00edfica, vol. 9, n. 1, p. 1836-1848, 2026.
https:\/\/doi.org\/10.61411\/rsc2026138019 <\/a>
DOI:<\/b> 10.61411\/rsc2026138019 <\/a>
\u00c1rea do conhecimento:<\/b> Ci\u00eancias da Sa\u00fade
Sub-\u00e1rea:<\/b> Nutri\u00e7\u00e3o
Palavras-chave:<\/b> Prote\u00ednas da Dieta; Metionina; Homociste\u00edna; Permeabilidade Intestinal; Sustentabilidade.
Publicado:<\/b> 1\u00ba de julho de 2026. <\/p>\n

.
\n Resumo<\/b> <\/p>\n

O padr\u00e3o diet\u00e9tico contempor\u00e2neo ocidental, caracterizado pelo consumo hiperproteico de origem predominantemente animal, tem sido correlacionado ao incremento de Doen\u00e7as Cr\u00f4nicas N\u00e3o Transmiss\u00edveis (DCNTs). Este estudo revisa as implica\u00e7\u00f5es bioqu\u00edmicas e fisiol\u00f3gicas da transi\u00e7\u00e3o da ingest\u00e3o de prote\u00ednas animais para vegetais, com foco na modula\u00e7\u00e3o do eixo metionina-homociste\u00edna, no custo bioenerg\u00e9tico g\u00e1strico e nas altera\u00e7\u00f5es da permeabilidade da barreira intestinal (leaky gut). Atrav\u00e9s de uma revis\u00e3o qualitativa da literatura, evidenciou-se que a redu\u00e7\u00e3o do aporte de metionina diet\u00e9tica atenua os n\u00edveis de homociste\u00edna plasm\u00e1tica, minimizando o risco cardiovascular e o estresse oxidativo endotelial. Fisiologicamente, as prote\u00ednas vegetais demandam menor acidez g\u00e1strica extrema para a desnatura\u00e7\u00e3o e clivagem proteica, otimizando o gasto de ATP celular e mitigando a sobrecarga glomerular decorrente de subprodutos nitrogenados. Conclui-se que a estrat\u00e9gia da transi\u00e7\u00e3o proteica atua de forma preventiva e terap\u00eautica na causa raiz de dist\u00farbios metab\u00f3licos cr\u00f4nicos, alinhando-se \u00e0s metas de sa\u00fade integrativa e sustentabilidade global da Agenda 2030 da ONU.<\/p>\n

Artigo<\/a>
\n.
\nSum\u00e1rio<\/a>
\n.<\/p>\n

\"\"<\/p>\n

.<\/p>\n

<\/p>\n","protected":false},"excerpt":{"rendered":"Transi\u00e7\u00e3o proteica na modula\u00e7\u00e3o metab\u00f3lica integrativa: implica\u00e7\u00f5es no eixo metionina-homociste\u00edna, bioenerg\u00e9tica g\u00e1strica e permeabilidade intestinal Lilian de Cassia…\n","protected":false},"author":2,"featured_media":12347,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_share_on_mastodon":"0"},"categories":[86],"tags":[70905,70906,70907,29610,29611,29612,5080,5081,70908,70909,70910,70911,29615,29616,29617,29618,29619,70912,70913,70914,70915,70916,70917,70918,70919,70920,70921,70922,70923,40181,70924,70925,70926,70927,70928,70929,70930,31335,5112,70931,21720,70932,70933,70934,70935,116,29662,29663,70936,70937,29665,5130,70938,70939,29666,70940,29668,70941,70942,5143,70943,70944,70945,70946,70947,5147,5148,70948,70949,29676,70950,70951,70952,70953,19452,70954,29677,29678,70955,5152,5153,5154,70956,70957,70958,70959,32,70960,70961,70962,70963,70964,70965,70966,70967,70968,33,5158,5160,5161,5162,5163,5164,5165,5166,5167,29686,29687,29688,29689,29690,29691,29692,29693,29694,5168,5169,29695,5170,5175,5176,5177,5178,5179,5180,5181,70969,4431,70970,117,70971,5183,29704,29705,29706,70972,70973,70974,5193,5194,5195,29710,70975,70976,70977,70978,70979,70980,70981],"class_list":["post-440749","post","type-post","status-publish","format-standard","has-post-thumbnail","category-saude","tag-acidez-gastrica","tag-agenda-2030","tag-animal-proteins","tag-article-submission","tag-article-submissions","tag-article-template","tag-artigo-cientifico","tag-artigo-online","tag-atp-celular","tag-barreira-intestinal","tag-barrera-intestinal","tag-bioenergetica-gastrica","tag-brazilian-journal","tag-brazilian-journals","tag-brazilian-scientific-journal","tag-capes-journal","tag-capes-qualis","tag-cardiovascular-risk","tag-cellular-atp","tag-chronic-non-communicable-diseases","tag-clivagem-enzimatica","tag-dcnts","tag-desechos-nitrogenados","tag-desnaturacao-proteica","tag-desnaturalizacion-proteica","tag-dieta-hiperproteica","tag-dietary-therapy","tag-digestao-proteica","tag-digestion-de-proteinas","tag-doencas-metabolicas","tag-eixo-metionina-homocisteina","tag-eje-metionina-homocisteina","tag-energy-expenditure","tag-enfermedades-cronicas-no-transmisibles","tag-enzymatic-cleavage","tag-escision-enzimatica","tag-estres-oxidativo","tag-estresse-oxidativo","tag-fator-de-imapacto","tag-food-sustainability","tag-gasto-energetico","tag-gastric-acidity","tag-gastric-bioenergetics","tag-glomerular-overload","tag-gut-barrier","tag-health","tag-high-impact-journal","tag-high-impact-journals","tag-high-protein-diet","tag-homocisteina-plasmatica","tag-impact-factor","tag-impacto-factor","tag-integrative-health","tag-integrative-metabolic-modulation","tag-international-journal","tag-intestinal-permeability","tag-journal","tag-leaky-gut","tag-leaky-gut-syndrome","tag-livro-cientifico","tag-metabolic-disorders","tag-metabolismo-da-metionina","tag-metabolismo-de-la-metionina","tag-methionine-metabolism","tag-methionine-homocysteine-axis","tag-modelo-de-artigo","tag-modelo-de-artigo-cientifico","tag-modulacao-metabolica","tag-modulacion-metabolica-integrativa","tag-national-journal","tag-nitrogenous-waste","tag-nutricion-clinica","tag-nutrition-science","tag-nutritional-prevention","tag-nutrologia","tag-objetivos-de-desarrollo-sostenible","tag-online-article","tag-online-journal","tag-oxidative-stress","tag-periodico","tag-periodico-da-capes","tag-periodico-nacional","tag-permeabilidad-intestinal","tag-permeabilidade-intestinal","tag-plant-based-proteins","tag-plasma-homocysteine","tag-portugal","tag-prevencao-nutricional","tag-prevencion-nutricional","tag-protein-denaturation","tag-protein-digestion","tag-protein-transition","tag-proteinas-animais","tag-proteinas-animales","tag-proteinas-vegetais","tag-proteinas-vegetales","tag-pt","tag-publciar-resumo","tag-publicar-artigo","tag-publicar-artigo-cientifico","tag-publicar-capitulo-de-livro","tag-publicar-dissertacao","tag-publicar-monografia","tag-publicar-resumo-cientifico","tag-publicar-tcc","tag-publicar-tese","tag-publish-abstract","tag-publish-article","tag-publish-book-chapter","tag-publish-dissertation","tag-publish-monograph","tag-publish-scientific-abstract","tag-publish-scientific-article","tag-publish-thesis","tag-publish-undergraduate-thesis","tag-qualis","tag-qualis-capes","tag-qualis-reference","tag-qualis-referencia","tag-revista-brasileira","tag-revista-cientifica-brasileira","tag-revista-de-impacto","tag-revista-internacional","tag-revista-online","tag-revistas-brasilieras","tag-revistas-de-impacto","tag-riesgo-cardiovascular","tag-risco-cardiovascular","tag-salud-integrativa","tag-saude","tag-saude-integrativa","tag-scielo","tag-scientific-article","tag-scientific-article-template","tag-scientific-book","tag-sindrome-del-intestino-permeable","tag-sobrecarga-glomerular","tag-sostenibilidad-alimentaria","tag-submeter-artigo","tag-submissao-de-artigo","tag-submissao-de-artigos","tag-submit-article","tag-subprodutos-nitrogenados","tag-sustentabilidade-alimentar","tag-terapeutica-dietetica","tag-terapia-dietetica","tag-transicao-proteica","tag-transicion-proteica","tag-trastornos-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