Duminica, 05 Aprilie 2026, ora 11:16<\/p>\n
1984 citiri<\/p>\n
O echip\u0103 de cercet\u0103tori de la Institutul Karolinska a testat o terapie genic\u0103 nou\u0103 care ar putea schimba complet modul \u00een care este tratat\u0103 surditatea din na\u0219tere.<\/p>\n
Tratamentul este simplu ca idee, cu o singur\u0103 injec\u021bie \u00een urechea intern\u0103, care ajut\u0103 organismul s\u0103 repare problema genetic\u0103 ce \u00eempiedic\u0103 auzul. Studiul, publicat \u00een Nature Medicine, a fost f\u0103cut pe 10 pacien\u021bi, cu v\u00e2rste \u00eentre 1 \u0219i 24 de ani, to\u021bi av\u00e2nd aceea\u0219i cauz\u0103 a surdit\u0103\u021bii, o muta\u021bie a genei OTOF.<\/p>\n
Cum func\u021bioneaz\u0103 tratamentul<\/p>\n
Problema acestor pacien\u021bi este c\u0103 organismul nu produce corect o protein\u0103 esen\u021bial\u0103 pentru auz, numit\u0103 otoferlin\u0103. F\u0103r\u0103 ea, sunetele nu sunt transmise corect c\u0103tre creier.<\/p>\n
Medicii au folosit un virus modificat (AAV) ca \u201evehicul\u201d pentru a introduce o versiune func\u021bional\u0103 a genei direct \u00een urechea intern\u0103.<\/p>\n
Procedura presupune o injec\u021bie f\u0103cut\u0103 \u00eentr-o zon\u0103 numit\u0103 \u201efereastra rotund\u0103\u201d, la baza cohleei. Practic, este o interven\u021bie local\u0103, nu un tratament de lung\u0103 durat\u0103. Efectele nu au \u00eent\u00e2rziat s\u0103 apar\u0103. \u00cen aproximativ o lun\u0103, majoritatea pacien\u021bilor au \u00eenceput s\u0103 aud\u0103 din nou, cel pu\u021bin par\u021bial.<\/p>\n
Dup\u0103 \u0219ase luni, diferen\u021ba a fost clar\u0103: nivelul sunetelor pe care \u00eel puteau percepe a sc\u0103zut de la 106 decibeli la 52 de decibeli, ceea ce \u00eenseamn\u0103 un progres major.<\/p>\n
Copiii \u00eentre 5 \u0219i 8 ani au avut cele mai bune rezultate, dar \u00eembun\u0103t\u0103\u021biri s-au v\u0103zut \u0219i la pacien\u021bii adul\u021bi.<\/p>\n
Cercet\u0103torii spun c\u0103 tratamentul a fost sigur \u00een perioada de testare \u0219i nu au ap\u0103rut reac\u021bii adverse grave.<\/p>\n
Chiar \u0219i a\u0219a, vorbim despre un studiu mic, iar terapia este \u00eenc\u0103 \u00een faz\u0103 experimental\u0103. Mai sunt necesare teste pe un num\u0103r mai mare de pacien\u021bi \u00eenainte s\u0103 devin\u0103 tratament standard.<\/p>\n
\u021ai-a pl\u0103cut articolul?<\/p>\n
Vrem s\u0103 producem mai multe, \u00eens\u0103 avem nevoie de sus\u021binerea ta. Orice dona\u021bie conteaz\u0103 pentru jurnalismul independent <\/p>\n","protected":false},"excerpt":{"rendered":"Duminica, 05 Aprilie 2026, ora 11:16 1984 citiri O echip\u0103 de cercet\u0103tori de la Institutul Karolinska a testat…\n","protected":false},"author":2,"featured_media":152323,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[12],"tags":[32,33,31,36,37,27,74,34,35,7718,25,41,40,38,39,192,26,124,28,29,30,71,72,73],"class_list":{"0":"post-152322","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-international","8":"tag-breaking-news","9":"tag-breakingnews","10":"tag-cele-mai-populare-subiecte","11":"tag-featured-news","12":"tag-featurednews","13":"tag-headlines","14":"tag-international","15":"tag-latest-news","16":"tag-latestnews","17":"tag-medicina","18":"tag-news","19":"tag-ro","20":"tag-romana","21":"tag-romania","22":"tag-romanian","23":"tag-stiinta","24":"tag-stiri","25":"tag-tehnologie","26":"tag-titluri","27":"tag-top-stories","28":"tag-topstories","29":"tag-world","30":"tag-world-news","31":"tag-worldnews"},"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@ro\/116352186051792577","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/ro\/wp-json\/wp\/v2\/posts\/152322","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/ro\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/ro\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ro\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ro\/wp-json\/wp\/v2\/comments?post=152322"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/ro\/wp-json\/wp\/v2\/posts\/152322\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ro\/wp-json\/wp\/v2\/media\/152323"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/ro\/wp-json\/wp\/v2\/media?parent=152322"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/ro\/wp-json\/wp\/v2\/categories?post=152322"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/ro\/wp-json\/wp\/v2\/tags?post=152322"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}