{"id":103347,"date":"2026-06-20T21:00:16","date_gmt":"2026-06-20T21:00:16","guid":{"rendered":"https:\/\/www.europesays.com\/sk\/103347\/"},"modified":"2026-06-20T21:00:16","modified_gmt":"2026-06-20T21:00:16","slug":"mozu-lieky-proti-alergii-zvysovat-riziko-demencie-vedci-upozornuju-hlavne-na-jeden-starsi-typ-antihistaminik-vosveteit-sk","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/sk\/103347\/","title":{"rendered":"M\u00f4\u017eu lieky proti alergii zvy\u0161ova\u0165 riziko demencie? Vedci upozor\u0148uj\u00fa hlavne na jeden star\u0161\u00ed typ antihistamin\u00edk | Vosveteit.sk"},"content":{"rendered":"

K\u00fdchanie, slzenie o\u010d\u00ed, upchat\u00fd nos a neust\u00e1le smrkanie. Pre mnoh\u00fdch \u013eud\u00ed patr\u00ed pe\u013eov\u00e1 sez\u00f3na medzi najmenej ob\u013e\u00faben\u00e9 obdobia roka, po\u010das ktor\u00e9ho siahaj\u00fa po antihistaminik\u00e1ch, ktor\u00e9 dok\u00e1\u017eu nepr\u00edjemn\u00e9 pr\u00edznaky alergie v\u00fdrazne zmierni\u0165. V posledn\u00fdch rokoch sa v\u0161ak objavili titulky, ktor\u00e9 vyvolali obavy. Niektor\u00e9 \u0161t\u00fadie toti\u017e nazna\u010dili mo\u017en\u00fa s\u00favislos\u0165 medzi ur\u010dit\u00fdmi liekmi proti alergii a vy\u0161\u0161\u00edm rizikom demencie<\/a>.<\/p>\n

Je naozaj d\u00f4vod na obavy? Odpove\u010f nie je tak\u00e1 jednoduch\u00e1, ako by sa mohlo zda\u0165. Antihistaminik\u00e1 patria medzi naj\u010dastej\u0161ie pou\u017e\u00edvan\u00e9 lieky proti sez\u00f3nnym alergi\u00e1m a ako ich n\u00e1zov napoved\u00e1, ich \u00falohou je blokova\u0165 histam\u00edn, l\u00e1tku, ktor\u00fa telo uvo\u013en\u00ed po\u010das alergickej reakcie. Pr\u00e1ve histam\u00edn sp\u00f4sobuje svrbenie, k\u00fdchanie, slzenie o\u010d\u00ed \u010di n\u00e1dchu. Nie v\u0161etky antihistaminik\u00e1 v\u0161ak funguj\u00fa rovnako.<\/p>\n

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Odoberaj Vosveteit.sk cez Telegram a prihl\u00e1s sa k odberu spr\u00e1v
\n <\/a><\/p>\n

Hlavne star\u0161ie antihistaminik\u00e1 sa dostali do pozornosti vedcov<\/p>\n

Star\u0161ie pr\u00edpravky prvej gener\u00e1cie, medzi ktor\u00e9 patr\u00ed napr\u00edklad difenhydram\u00edn alebo chlorfenam\u00edn, \u010dasto vyvolaj\u00fa ospalos\u0165 a \u00fanavu. Nov\u0161ie lieky druhej gener\u00e1cie, ako cetiriz\u00edn, loratad\u00edn alebo fexofenad\u00edn, tieto ved\u013eaj\u0161ie \u00fa\u010dinky zvy\u010dajne obmedzia. Pr\u00e1ve star\u0161ie lieky sa dostali do centra pozornosti vedcov, informuje port\u00e1l The Conversation.<\/a><\/p>\n

D\u00f4vod s\u00favis\u00ed s l\u00e1tkou naz\u00fdvanou acetylchol\u00edn. Ide o chemick\u00fa l\u00e1tku, ktor\u00e1 zohr\u00e1va d\u00f4le\u017eit\u00fa \u00falohu pri pam\u00e4ti, u\u010den\u00ed a s\u00fastreden\u00ed. Niektor\u00e9 star\u0161ie antihistaminik\u00e1 zni\u017euj\u00fa jeho aktivitu, \u010do m\u00f4\u017ee ovplyvni\u0165 fungovanie mozgu<\/a>. Lek\u00e1ri tak\u00e9to \u00fa\u010dinky ozna\u010duj\u00fa ako anticholinergn\u00e9.<\/p>\n

\"demencia-nastup-demencie\"\"demencia-nastup-demencie\"Zdroj: Pixel-Shot \/ shutterstock.com a Semnic \/ shutterstock.com, kol\u00e1\u017e Vedavovrecku.sk<\/p>\n

V\u00fdskumn\u00edci u\u017e dlh\u0161ie sk\u00famali, \u010di dlhodob\u00e9 u\u017e\u00edvanie liekov s v\u00fdrazn\u00fdm anticholinergn\u00fdm \u00fa\u010dinkom nes\u00favis\u00ed s vy\u0161\u0161\u00edm rizikom demencie. Nieko\u013eko ve\u013ek\u00fdch \u0161t\u00fadi\u00ed skuto\u010dne objavilo ur\u010dit\u00fa spojitos\u0165. \u013dudia s najvy\u0161\u0161ou dlhodobou expoz\u00edciou t\u00fdmto liekom \u010dastej\u0161ie trpeli demenciou ne\u017e t\u00ed, ktor\u00ed ich neu\u017e\u00edvali. To v\u0161ak automaticky neznamen\u00e1, \u017ee samotn\u00e9 lieky sp\u00f4sobuj\u00fa vznik ochorenia.<\/p>\n

Neprehliadni
\n <\/p>\n

\"Samsung\"Samsung <\/p>\n

\n\t\t\t\t\tTieto nov\u00e9 funkcie v Samsung telef\u00f3noch ti pom\u00f4\u017eu ochr\u00e1ni\u0165 s\u00fakromie. Cudz\u00ed \u010dlovek ved\u013ea teba u\u017e len tak neuvid\u00ed, \u010do rob\u00ed\u0161 na mobile <\/p>\n

<\/a><\/p>\n

Vedci upozornili na d\u00f4le\u017eit\u00fd probl\u00e9m. Takzvan\u00e9 observa\u010dn\u00e9 \u0161t\u00fadie s\u00edce dok\u00e1\u017eu n\u00e1js\u0165 vzorce a s\u00favislosti, no nedok\u00e1\u017eu potvrdi\u0165 pr\u00ed\u010dinu. \u013dudia u\u017e\u00edvaj\u00faci tieto lieky sa toti\u017e m\u00f4\u017eu od ostatn\u00fdch l\u00ed\u0161i\u0165 aj v \u010fal\u0161\u00edch faktoroch. Niektor\u00ed m\u00f4\u017eu trpie\u0165 in\u00fdmi zdravotn\u00fdmi probl\u00e9mami, ktor\u00e9 samy o sebe zvy\u0161uj\u00fa riziko demencie. U \u010fal\u0161\u00edch sa mohli prv\u00e9 pr\u00edznaky ochorenia objavi\u0165 e\u0161te pred za\u010diatkom lie\u010dby.<\/p>\n

V roku 2024 pribudla \u010fal\u0161ia \u0161t\u00fadia zameran\u00e1 na pacientov so sennou n\u00e1dchou. V\u00fdskumn\u00edci zaznamenali, \u017ee riziko demencie r\u00e1stlo spolu s celkov\u00fdm mno\u017estvom u\u017eit\u00fdch antihistamin\u00edk. Silnej\u0161ia s\u00favislos\u0165 sa objavila pri star\u0161\u00edch liekoch prvej gener\u00e1cie, no ur\u010dit\u00fd efekt sa uk\u00e1zal aj pri modernej\u0161\u00edch pr\u00edpravkoch, \u010do je pr\u00e1ve to, \u010do vedcov prekvapilo.<\/p>\n

Nov\u0161ie antihistaminik\u00e1 toti\u017e prenikaj\u00fa do mozgu podstatne menej a z\u00e1rove\u0148 vykazuj\u00fa slab\u0161ie anticholinergn\u00e9 \u00fa\u010dinky. \u010cas\u0165 odborn\u00edkov preto za\u010dala pochybova\u0165, \u010di probl\u00e9m naozaj sp\u00f4sobuj\u00fa samotn\u00e9 lieky.<\/p>\n

\u201eNie je ist\u00e9, \u017ee za pozorovanou s\u00favislos\u0165ou stoja priamo antihistaminik\u00e1. V\u00fdznamn\u00fa \u00falohu m\u00f4\u017eu zohr\u00e1va\u0165 aj \u010fal\u0161ie faktory vr\u00e1tane z\u00e1va\u017enosti alergie,\u201c upozornili odborn\u00edci.<\/p>\n

Mo\u017eno to nie je o samotn\u00fdch liekoch, ale o pridru\u017een\u00fdch faktoroch<\/p>\n

Samotn\u00e1 alergia toti\u017e m\u00f4\u017ee ovplyvni\u0165 viacero procesov, ktor\u00e9 s\u00favisia so zdrav\u00edm mozgu. Jedn\u00fdm z nich je sp\u00e1nok<\/a>. Upchat\u00fd nos, k\u00fdchanie alebo svrbenie o\u010d\u00ed \u010dasto naru\u0161ia no\u010dn\u00fd odpo\u010dinok. Vedci pritom u\u017e roky sp\u00e1jaj\u00fa nekvalitn\u00fd sp\u00e1nok s vy\u0161\u0161\u00edm rizikom kognit\u00edvnych probl\u00e9mov vo vy\u0161\u0161om veku. Objavila sa ale aj \u010fal\u0161ia mo\u017enos\u0165.<\/p>\n

\"choroba\"chorobaZdroj: Mojca-Peter a G.C. z Pixabay, kol\u00e1\u017e Vosveteit.sk<\/a><\/p>\n

Alergick\u00e1 n\u00e1dcha vyvol\u00e1va z\u00e1palov\u00fa reakciu imunitn\u00e9ho syst\u00e9mu. Niektor\u00ed v\u00fdskumn\u00edci sk\u00famaj\u00fa, \u010di dlhodob\u00fd z\u00e1pal<\/a> v tele nem\u00f4\u017ee ovplyvni\u0165 procesy spojen\u00e9 s rozvojom Alzheimerovej choroby a \u010fal\u0161\u00edch foriem demencie. Preto je dnes ve\u013emi n\u00e1ro\u010dn\u00e9 oddeli\u0165 \u00fa\u010dinok samotn\u00fdch liekov od \u00fa\u010dinkov alergie.<\/p>\n

\u010clovek s \u0165a\u017ekou formou sennej n\u00e1dchy toti\u017e u\u017e\u00edva viac liekov, z\u00e1rove\u0148 hor\u0161ie sp\u00ed a m\u00f4\u017ee trpie\u0165 v\u00fdraznej\u0161\u00edm z\u00e1palom. Ka\u017ed\u00fd z t\u00fdchto faktorov m\u00f4\u017ee ovplyvni\u0165 v\u00fdsledky v\u00fdskumov. Dobrou spr\u00e1vou s\u00fa nov\u0161ie \u00fadaje, napr\u00edklad rozsiahla celo\u0161t\u00e1tna \u0161t\u00fadia v Spojen\u00fdch \u0161t\u00e1toch neobjavila d\u00f4kazy, ktor\u00e9 by sp\u00e1jali dlhodob\u00e9 u\u017e\u00edvanie modern\u00fdch antihistamin\u00edk druhej gener\u00e1cie so zv\u00fd\u0161en\u00fdm rizikom demencie.<\/p>\n

\u201eNajnov\u0161ie v\u00fdskumy nenazna\u010dili, \u017ee by pravideln\u00e9 u\u017e\u00edvanie antihistamin\u00edk druhej gener\u00e1cie zvy\u0161ovalo riziko demencie,\u201c uv\u00e1dzaj\u00fa autori anal\u00fdz.<\/p>\n

V\u00fdskumn\u00edci upozor\u0148uj\u00fa, \u017ee nie v\u0161etky antihistaminik\u00e1 s\u00fa rovnak\u00e9<\/p>\n

To v\u0161ak neznamen\u00e1, \u017ee v\u0161etky lieky s\u00fa rovnak\u00e9. Odborn\u00edci st\u00e1le odpor\u00fa\u010daj\u00fa opatrnos\u0165 najm\u00e4 pri star\u0161\u00edch antihistaminik\u00e1ch, ktor\u00e9 sp\u00f4sobuj\u00fa ospalos\u0165 a zasahuj\u00fa do fungovania acetylchol\u00ednu. U star\u0161\u00edch \u013eud\u00ed m\u00f4\u017eu zv\u00fd\u0161i\u0165 riziko p\u00e1dov, probl\u00e9mov so s\u00fastreden\u00edm alebo dopravn\u00fdch neh\u00f4d. Ak alergiou trp\u00ed\u0161 pravidelne, oplat\u00ed sa skontrolova\u0165, ak\u00fd typ lieku u\u017e\u00edva\u0161.<\/p>\n

Mo\u017enost\u00ed existuje viac. Okrem modern\u00fdch antihistamin\u00edk m\u00f4\u017eu pom\u00f4c\u0165 aj nosov\u00e9 spreje<\/a> s obsahom kortikosteroidov, ktor\u00e9 zni\u017euj\u00fa z\u00e1pal priamo v nose. Pri ve\u013emi siln\u00fdch alergi\u00e1ch lek\u00e1ri niekedy odpor\u00fa\u010daj\u00fa aj alerg\u00e9nov\u00fa imunoterapiu, pri ktorej si organizmus postupne zvykne na l\u00e1tku vyvol\u00e1vaj\u00facu alergick\u00fa reakciu.<\/p>\n

\"nosovy\"nosovyZdroj: dimarik \/ depositphotos.com<\/a><\/p>\n

S\u00fa\u010dasn\u00e9 poznatky teda nepon\u00fakaj\u00fa jednoduch\u00fa odpove\u010f. Star\u0161ie antihistaminik\u00e1 maj\u00fa svoje nev\u00fdhody a odborn\u00edci ich odpor\u00fa\u010daj\u00fa pou\u017e\u00edva\u0165 opatrne, najm\u00e4 vo vy\u0161\u0161om veku. Pri nov\u0161\u00edch liekoch v\u0161ak vedci zatia\u013e nena\u0161li presved\u010div\u00e9 d\u00f4kazy, ktor\u00e9 by nazna\u010dili v\u00fdraznej\u0161ie zv\u00fd\u0161enie rizika demencie. Preto sa pri v\u00fdbere lie\u010dby oplat\u00ed zoh\u013eadni\u0165 nielen \u00fa\u010dinnos\u0165, ale aj celkov\u00fd zdravotn\u00fd stav a odpor\u00fa\u010dania lek\u00e1ra \u010di lek\u00e1rnika.<\/p>\n


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<\/p>\n","protected":false},"excerpt":{"rendered":"K\u00fdchanie, slzenie o\u010d\u00ed, upchat\u00fd nos a neust\u00e1le smrkanie. Pre mnoh\u00fdch \u013eud\u00ed patr\u00ed pe\u013eov\u00e1 sez\u00f3na medzi najmenej ob\u013e\u00faben\u00e9 obdobia…\n","protected":false},"author":2,"featured_media":103348,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_share_on_mastodon":"0"},"categories":[8],"tags":[12603,35322,11706,8214,35323,33,35324,35325,43,40,42,4039,36,35326,50,35327,745,3307,49,48,35328,35329],"class_list":["post-103347","post","type-post","status-publish","format-standard","has-post-thumbnail","category-svet","tag-alergie","tag-antihistaminika","tag-clovek","tag-demencia","tag-kychanie","tag-news","tag-riziko-demencie","tag-senna-nadcha","tag-sk","tag-slovak","tag-slovencina","tag-spanok","tag-spravy","tag-starsie-antihistaminika","tag-svet","tag-upchaty-nos","tag-vyskum","tag-vysledky","tag-world","tag-world-news","tag-zapal","tag-zvysuju-antihistaminika-riziko-demencie"],"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@sk\/116784452757808004","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/sk\/wp-json\/wp\/v2\/posts\/103347","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/sk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/sk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/sk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/sk\/wp-json\/wp\/v2\/comments?post=103347"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/sk\/wp-json\/wp\/v2\/posts\/103347\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/sk\/wp-json\/wp\/v2\/media\/103348"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/sk\/wp-json\/wp\/v2\/media?parent=103347"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/sk\/wp-json\/wp\/v2\/categories?post=103347"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/sk\/wp-json\/wp\/v2\/tags?post=103347"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}