{"id":127611,"date":"2026-07-18T18:01:08","date_gmt":"2026-07-18T18:01:08","guid":{"rendered":"https:\/\/www.europesays.com\/sk\/127611\/"},"modified":"2026-07-18T18:01:08","modified_gmt":"2026-07-18T18:01:08","slug":"bolest-klbov-by-sa-raz-mohla-liecit-bez-tabletiek-a-operacie-vedci-prinutili-imunitne-bunky-aby-namiesto-nicenia-zacali-opravovat-tkanivo-vosveteit-sk","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/sk\/127611\/","title":{"rendered":"Boles\u0165 k\u013abov by sa raz mohla lie\u010di\u0165 bez tabletiek a oper\u00e1cie. Vedci prin\u00fatili imunitn\u00e9 bunky, aby namiesto ni\u010denia za\u010dali opravova\u0165 tkanivo | Vosveteit.sk"},"content":{"rendered":"

Boles\u0165 k\u013abov tr\u00e1pi \u010doraz viac \u013eud\u00ed a jedn\u00fdm z hlavn\u00fdch probl\u00e9mov zost\u00e1va dlhodob\u00fd z\u00e1pal. Ten s\u00edce vznik\u00e1 ako prirodzen\u00e1 obrana tela po zranen\u00ed, no ak pretrv\u00e1va pr\u00edli\u0161 dlho, m\u00f4\u017ee po\u0161kodzova\u0165 zdrav\u00e9 tkaniv\u00e1 a ur\u00fdch\u013eova\u0165 opotrebovanie k\u013abov.<\/p>\n

Vedci z University of Alabama in Huntsville<\/a> (UAH) teraz sk\u00famali nov\u00fd pr\u00edstup, ktor\u00fd by mohol pom\u00f4c\u0165 telu prepn\u00fa\u0165 z re\u017eimu neust\u00e1leho boja do re\u017eimu opravy. Vyu\u017eili pritom nie lieky, ale n\u00edzko intenz\u00edvny ultrazvuk. V\u00fdsledky v\u00fdskumu nazna\u010duj\u00fa, \u017ee pravideln\u00fd ultrazvukov\u00fd sign\u00e1l m\u00f4\u017ee ovplyvni\u0165 spr\u00e1vanie imunitn\u00fdch buniek a podpori\u0165 procesy spojen\u00e9 s hojen\u00edm po\u0161koden\u00fdch k\u013abov. Zatia\u013e v\u0161ak ide iba o laborat\u00f3rny v\u00fdskum a vedci musia technol\u00f3giu e\u0161te overi\u0165 na zvierac\u00edch modeloch.<\/p>\n

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Odoberaj Vosveteit.sk cez Telegram a prihl\u00e1s sa k odberu spr\u00e1v
\n <\/a><\/p>\n

Imunitn\u00e9 bunky m\u00f4\u017eu pom\u00e1ha\u0165 aj \u0161kodi\u0165<\/p>\n

Po zranen\u00ed k\u013abu telo okam\u017eite spust\u00ed obrann\u00fa reakciu. Do po\u0161koden\u00e9ho miesta zamieria \u0161peci\u00e1lne imunitn\u00e9 bunky naz\u00fdvan\u00e9 makrof\u00e1gy. Ich \u00falohou je odstr\u00e1ni\u0165 po\u0161koden\u00e9 \u010dasti tkaniva a pripravi\u0165 priestor na obnovu. Tieto bunky v\u0161ak maj\u00fa dve rozdielne \u00falohy.<\/p>\n

Prv\u00e1 skupina, ozna\u010dovan\u00e1 ako M1 makrof\u00e1gy, podporuje z\u00e1pal. Pom\u00e1ha telu bojova\u0165 proti po\u0161kodeniu alebo infekcii, no ak zostane akt\u00edvna pr\u00edli\u0161 dlho, m\u00f4\u017ee za\u010da\u0165 ni\u010di\u0165 aj zdrav\u00e9 bunky. Druh\u00e1 skupina, zn\u00e1ma ako M2 makrof\u00e1gy, podporuje opravu tkan\u00edv a regener\u00e1ciu. Pr\u00e1ve rovnov\u00e1ha medzi t\u00fdmito dvoma stavmi m\u00f4\u017ee rozhodn\u00fa\u0165 o tom, \u010di sa k\u013ab spr\u00e1vne zahoj\u00ed alebo sa v \u0148om rozvinie dlhodob\u00fd probl\u00e9m.<\/p>\n

\"V\u00fdskumn\u00edci\"V\u00fdskumn\u00edciZdroj: AI, Vosveteit.sk<\/p>\n

\u201ePo zranen\u00ed telo privol\u00e1 z\u00e1palov\u00e9 obrann\u00e9 makrof\u00e1gy M1, ktor\u00e9 odstra\u0148uj\u00fa po\u0161koden\u00e9 tkanivo, a opravn\u00e9 makrof\u00e1gy M2, ktor\u00e9 podporuj\u00fa hojenie. Ak v\u0161ak prevl\u00e1daj\u00fa obrann\u00e9 bunky pr\u00edli\u0161 dlho, m\u00f4\u017ee vznikn\u00fa\u0165 prostredie, ktor\u00e9 prispieva k po\u0161kodeniu k\u013abu,\u201c vysvet\u013euje profesorka Anuradha Subramanian z UAH.<\/p>\n

Pr\u00e1ve tento proces zohr\u00e1va v\u00fdznamn\u00fa \u00falohu pri takzvanej posttraumatickej artr\u00f3ze, ktor\u00e1 m\u00f4\u017ee vznikn\u00fa\u0165 po \u00farazoch k\u013abov.<\/p>\n

Neprehliadni
\n <\/p>\n

\"vladimir\"vladimir <\/p>\n

\n\t\t\t\t\tHackeri odhalili z\u00e1kulisie ruskej cenz\u00fary. M\u00e9di\u00e1 mali zataji\u0165 palivov\u00fa kr\u00edzu aj z\u00e1bery z \u00fatoku na Moskvu <\/p>\n

<\/a><\/p>\n

Ultrazvuk bez liekov men\u00ed spr\u00e1vanie buniek<\/p>\n

V\u00fdskumn\u00fd t\u00edm sk\u00famal, \u010di dok\u00e1\u017ee n\u00edzko intenz\u00edvny ultrazvuk<\/a> ovplyvni\u0165 spr\u00e1vanie makrof\u00e1gov. Na rozdiel od be\u017en\u00fdch ultrazvukov\u00fdch vy\u0161etren\u00ed i\u0161lo o \u0161peci\u00e1lne nastaven\u00fd sign\u00e1l s n\u00edzkou intenzitou, ktor\u00fd nemal po\u0161kodzova\u0165 tkanivo. Vedci vytvorili model, ktor\u00fd mal \u010do najlep\u0161ie napodobni\u0165 situ\u00e1ciu po skuto\u010dnom zranen\u00ed. Nepou\u017eili iba tradi\u010dn\u00e9 laborat\u00f3rne met\u00f3dy na vyvolanie z\u00e1palu, ale pridali aj fragmenty fibronekt\u00ednu, molekuly, ktor\u00e9 vznikaj\u00fa pri rozpade tkan\u00edv.<\/p>\n

Tento postup mal lep\u0161ie zachyti\u0165 podmienky, ktor\u00e9 vznikaj\u00fa priamo v po\u0161kodenom k\u013abe. V\u00fdsledky uk\u00e1zali, \u017ee ultrazvuk zn\u00ed\u017eil mno\u017estvo ukazovate\u013eov spojen\u00fdch so z\u00e1palom a z\u00e1rove\u0148 zv\u00fd\u0161il aktivitu g\u00e9nov typick\u00fdch pre opravn\u00fd stav makrof\u00e1gov. Bunky sa teda pod\u013ea v\u00fdsledkov v\u00fdskumu za\u010dali viac spr\u00e1va\u0165 ako pomocn\u00edci pri obnove tkaniva ne\u017e ako neust\u00e1le zapnut\u00fd obrann\u00fd syst\u00e9m.<\/p>\n

Aby pochopili, \u010do sa v bunk\u00e1ch deje, v\u00fdskumn\u00edci vyu\u017eili modern\u00fa anal\u00fdzu g\u00e9novej aktivity naz\u00fdvan\u00fa transkriptomika. T\u00e1 umo\u017e\u0148uje sledova\u0165, ktor\u00e9 g\u00e9ny<\/a> sa v bunke aktivuj\u00fa a ktor\u00e9 naopak zost\u00e1vaj\u00fa menej akt\u00edvne. Vedci v\u0161ak nehodnotili iba jednotliv\u00e9 g\u00e9ny, ale h\u013eadali aj skupiny g\u00e9nov, ktor\u00e9 reagovali podobn\u00fdm sp\u00f4sobom.<\/p>\n

Na tento \u00fa\u010del pou\u017eili met\u00f3du s n\u00e1zvom diferenci\u00e1lne zhlukovanie. T\u00e1 pomohla odhali\u0165 \u0161ir\u0161ie zmeny v spr\u00e1van\u00ed buniek po p\u00f4soben\u00ed ultrazvuku.<\/p>\n

\u201eV\u010faka tejto met\u00f3de sme mohli sk\u00fama\u0165 nielen to, ktor\u00e9 g\u00e9ny sa zmenili, ale aj to, ako cel\u00e9 skupiny g\u00e9nov menili svoje spolo\u010dn\u00e9 spr\u00e1vanie po ultrazvukovej stimul\u00e1cii,\u201c vysvetlil profesor Satyaki Roy.<\/p>\n

Tak\u00fdto poh\u013ead m\u00f4\u017ee vedcom pom\u00f4c\u0165 lep\u0161ie pochopi\u0165, ako fyzik\u00e1lne podnety ovplyv\u0148uj\u00fa imunitn\u00fd syst\u00e9m.<\/p>\n

\"koleno\"kolenoZdroj: jeffy1139 \/ depositphotos.com<\/a>
\nNov\u00e1 mo\u017enos\u0165 pri lie\u010dbe artr\u00f3zy?<\/p>\n

Ak sa v\u00fdsledky potvrdia v \u010fal\u0161\u00edch experimentoch, n\u00edzko intenz\u00edvny ultrazvuk by raz mohol doplni\u0165 existuj\u00face met\u00f3dy lie\u010dby po\u0161koden\u00fdch k\u013abov. V\u00fdhodou tejto technol\u00f3gie je, \u017ee nevyu\u017e\u00edva lieky a nevy\u017eaduje chirurgick\u00fd z\u00e1krok. Mohla by preto predstavova\u0165 zauj\u00edmav\u00fa mo\u017enos\u0165 pri stavoch, kde z\u00e1pal brzd\u00ed prirodzen\u00fa obnovu tkan\u00edv.<\/p>\n

\u201ePosttraumatick\u00e1 artr\u00f3za s\u00favis\u00ed aj s pretrv\u00e1vaj\u00facim z\u00e1palom, ktor\u00fd obmedzuje opravu tkan\u00edv a ur\u00fdch\u013euje po\u0161kodzovanie k\u013abov. N\u00edzko intenz\u00edvny ultrazvuk pon\u00faka mo\u017enos\u0165 ovplyvni\u0165 spr\u00e1vanie imunitn\u00fdch buniek bez liekov a bez invaz\u00edvneho z\u00e1sahu,\u201c tvrd\u00ed Roy.<\/p>\n

Vedci teraz pl\u00e1nuj\u00fa \u010fal\u0161ie kroky. Chc\u00fa overi\u0165 \u00fa\u010dinky technol\u00f3gie na zvierac\u00edch modeloch skor\u00e9ho \u0161t\u00e1dia posttraumatickej artr\u00f3zy a sledova\u0165, \u010di zmena spr\u00e1vania imunitn\u00fdch buniek skuto\u010dne povedie k lep\u0161iemu dlhodob\u00e9mu hojeniu.<\/p>\n

Ak \u010fal\u0161ie testy dopadn\u00fa priaznivo, ultrazvuk by v bud\u00facnosti mohol patri\u0165 medzi n\u00e1stroje, ktor\u00e9 nep\u00f4sobia iba proti bolesti<\/a>, ale pom\u00e1haj\u00fa telu lep\u0161ie riadi\u0165 samotn\u00fd proces opravy po\u0161koden\u00fdch k\u013abov.<\/p>\n


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<\/p>\n","protected":false},"excerpt":{"rendered":"Boles\u0165 k\u013abov tr\u00e1pi \u010doraz viac \u013eud\u00ed a jedn\u00fdm z hlavn\u00fdch probl\u00e9mov zost\u00e1va dlhodob\u00fd z\u00e1pal. Ten s\u00edce vznik\u00e1 ako…\n","protected":false},"author":2,"featured_media":127612,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_share_on_mastodon":"0"},"categories":[8],"tags":[40674,13925,11706,20949,40675,4524,33,2449,40676,43,40,42,36,50,40677,49,48,463],"class_list":["post-127611","post","type-post","status-publish","format-standard","has-post-thumbnail","category-svet","tag-artroza","tag-bolest","tag-clovek","tag-imunitny-system","tag-klb","tag-liecba","tag-news","tag-pomoc","tag-poskodeny-klb","tag-sk","tag-slovak","tag-slovencina","tag-spravy","tag-svet","tag-ultrazvuk","tag-world","tag-world-news","tag-zdravie"],"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@sk\/116942293568813374","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/sk\/wp-json\/wp\/v2\/posts\/127611","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/sk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/sk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/sk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/sk\/wp-json\/wp\/v2\/comments?post=127611"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/sk\/wp-json\/wp\/v2\/posts\/127611\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/sk\/wp-json\/wp\/v2\/media\/127612"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/sk\/wp-json\/wp\/v2\/media?parent=127611"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/sk\/wp-json\/wp\/v2\/categories?post=127611"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/sk\/wp-json\/wp\/v2\/tags?post=127611"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}