Resolution of R-loops and transcription–replication conflicts by SETX–BRCA1–BARD1 complex
Niehrs, C. & Luke, B. Regulatory R-loops as facilitators of gene expression and genome stability. Nat. Rev. Mol.…
‘An AlphaFold 4’ – scientists marvel at DeepMind drug spin-off’s exclusive new AI
The AI tool includes predictions of how proteins interact with potential therapeutic molecules.Credit: Isomorphic Labs Nearly two years…
Synthesis, characterization, DFT analysis, molecular docking and anticancer investigations in colorectal carcinoma of a novel pyrazole-hydrazone zinc(II) complex
Synthesis and characterization In the first step to access the zinc complex, ring closure occurred in the reaction…
Single-cell multi-omics analysis reveals cancer regulatory elements of transcriptional programs and clinical implications
Single-cell transcriptional and chromatin accessibility profiling in diverse carcinomas To elucidate the chromatin and transcriptional features of human…