Police have been diverting traffic from Colmore Circus Queensway down to Snowhill Queensway.
Transport for West Midlands has urged bus passengers to plan ahead, writing on X: “City centre buses are unable to access Colmore Row due to a building fire.
“Birmingham services entering the city via Snow Hill Queensway will do a U-turn and exit the city via the same route. Bus stops on Colmore Row area can not be served.
“Bus stops on Colmore Row, Livery Street, Edmund Street, Newhall Street, and Margaret Street are unable to be served.
“Nearest bus stops in use to exit the city are on Snow Hill Queensway outbound, or Great Charles Street Queensway.”