Round Three of the PREM campaign is here, with five huge derby matches to get stuck into across the weekend.
The action gets underway in the North West, as Sale Sharks welcome Newcastle Red Bulls to the CorpAcq Stadium, with both sides looking to hit back after defeats last time out.
Things hot up on Saturday, with three more enthralling contests. The day gets underway at Ashton Gate, as Bristol Bears take on a resurgent Exeter Chiefs, before Northampton Saints face Leicester Tigers in the latest chapter of the East Midlands derby, while Bath and Gloucester also square off in the West Country derby later that evening.
Rounding off the weekend of the season, we head to the Capital as Harlequins take on Saracens.
Check on all the PREM teams, here.
Friday
Sale Sharks v Newcastle Red Bulls
Sale Sharks: 15 Joe Carpenter, 14 Tom Roebuck, 13 Rob du Preez, 12 Marius Louw, 11 Arron Reed, 10 George Ford, 9 Gus Warr, 8 Sam Dugdale, 7 Tristan Woodman, 6 Ernst van Rhyn (c), 5 Hyron Andrews, 4 Ben Bamber, 3 Asher Opoku-Fordjour, 2 Luke Cowan-Dickie, 1 Bevan Rodd
Replacements: 16 Nathan Jibulu, 17 Simon McIntyre, 18 James Harper, 19 Tom Burrow, 20 Ethan Caine, 21 Raffi Quirke, 22 Tom O’Flaherty, 23 Sam Bedlow
Newcastle Red Bulls: 15 Ethan Grayson, 14 Elliott Obatoyinbo, 13 Connor Doherty, 12 Max Clark, 11 Alex Hearle, 10 Boeta Chamberlain, 9 James Elliott, 8 Amanaki Mafi, 7 Tom Gordon, 6 Fergus Lee-Warner, 5 Freddie Clarke, 4 Jamie Hodgson, 3 Richard Palframan, 2 George McGuigan (c), 1 Adam Brocklebank
Replacements: 16 Ollie Fletcher, 17 Micky Rewcastle, 18 Murray McCallum, 19 Oscar Usher, 20 Cameron Neild, 21 Simon Benitez Cruz, 22 Brett Connon, 23 Oli Spencer
Venue: CorpAcq Stadium
Kick-off: 19:45 BST
Where to watch: TNT Sports 1, TNT Sports Ultimate and Discovery+
Referee: Joe James
Assistant Referees: Hamish Smales and Wayne Falla
TMO: Andrew Jackson
Saturday
Bristol Bears v Exeter Chiefs
Bristol Bears: 15 Benjamin Elizalde, 14 Josh Carrington, 13 Jack Bates, 12 Benhard Janse van Rensburg, 11 Kalaveti Ravouvou, 10 Tom Jordan, 9 Kieran Marmion, 8 Viliame Mata, 7 Fitz Harding (c), 6 Santiago Grondona, 5 Joe Batley, 4 Pedro Rubiolo, 3 George Kloska, 2 Gabriel Oghre, 1 Ellis Genge
Replacements: 16 Harry Thacker, 17 Jake Woolmore, 18 Lovejoy Chawatama, 19 James Dun, 20 Joe Owen, 21 Oscar Lennon, 22 Sam Worsley, 23 Max Pepper
Exeter Chiefs: 15 Dan John, 14 Immanuel Feyi-Waboso, 13 Henry Slade, 12 Ben Hammersley, 11 Paul Brown-Bampoe, 10 Harvey Skinner, 9 Stephen Varney, 8 Ross Vintcent, 7 Greg Fisilau, 6 Ethan Roots, 5 Andrea Zambonin, 4 Dafydd Jenkins (c), 3 Josh Iosefa-Scott, 2 Jack Yeandle, 1 Will Goodrick-Clarke
Replacements: 16 Julian Heaven, 17 Ethan Burger, 18 Bachuki Tchumbadze, 19 Rusi Tuima, 20 Lewis Pearson, 21 Kane James, 22 Charlie Chapman, 23 Nick Lilley
Venue: Ashton Gate
Kick-off: 15:00 BST
Where to watch: TNT Sports Extra, Discovery+
Referee: Anthony Woodthorpe
Assistant Referees: Matthew Carley and Simon Harding
TMO: David Rose
Northampton Saints v Leicester Tigers
Northampton Saints: 15 George Hendy, 14 Tommy Freeman, 13 Rory Hutchinson, 12 Fraser Dingwall, 11 Edoardo Todaro, 10 Fin Smith, 9 Alex Mitchell, 8 Callum Chick (c), 7 Tom Pearson, 6 Alex Coles, 5 JJ van der Mescht, 4 Tom Lockett, 3 Trevor Davison, 2 Robbie Smith, 1 Emmanuel Iyogun
Replacements: 16 Craig Wright, 17 Danilo Fischetti, 18 Luke Green, 19 Josh Kemeny, 20 Henry Pollock, 21 Archie McParland, 22 Anthony Belleau, 23 Tom Litchfield
Leicester Tigers: 15 Freddie Steward, 14 Adam Radwan, 13 Will Wand, 12 Solomone Kata, 11 Ollie Hassell-Collins, 10 Billy Searle, 9 Jack van Poortvliet, 8 Emeka Ilione, 7 Tommy Reffell, 6 Hanro Liebenberg, 5 Ollie Chessum (c), 4 Harry Wells, 3 Joe Heyes, 2 Jamie Blamire, 1 Nicky Smith
Replacements: 16 Charlie Clare, 17 Tarek Haffar, 18 Will Hurd, 19 Joaquín Moro, 20 Olly Cracknell, 21 Tom Whiteley, 22 James O’Connor, 23 Orlando Bailey
Venue: Franklin’s Gardens
Kick-off: 15:15 BST
Where to watch: TNT Sports 1, TNT Sports Ultimate and Discovery+
Referee: Luke Pearce
Assistant Referees: Alex Thomas and John Meredith
TMO: Peter Allan
Bath v Gloucester
Bath: 15 Tom de Glanville, 14 Joe Cokanasiga, 13 Ollie Lawrence, 12 Max Ojomoh, 11 Henry Arundell, 10 Finn Russell (c), 9 Tom Carr-Smith, 8 Josh Bayliss, 7 Sam Underhill, 6 Guy Pepper, 5 Ross Molony, 4 Ewan Richards, 3 Will Stuart, 2 Tom Dunn, 1 Beno Obano
Replacements: 16 Kepu Tuipulotu, 17 Francois van Wyk, 18 Thomas du Toit, 19 Miles Reid, 20 Alfie Barbeary, 21 Neil le Roux, 22 Santi Carreras, 23 Chris Harris
Gloucester: 15 Charlie Atkinson, 14 Ben Loader, 13 Will Joseph, 12 Seb Atkinson, 11 Ollie Thorley, 10 Ross Byrne, 9 Tomos Williams (c), 8 Josh Basham, 7 James Venter, 6 Freddie Thomas, 5 Matias Alemanno, 4 Cam Jordan, 3 Nepo Laulala, 2 Seb Blake, 1 Ciaran Knight
Replacements: 16 Jack Innard, 17 Archie McArthur, 18 Afolabi Fasogbon, 19 Hugh Bokenham, 20 Jack Mann, 21 Harry Taylor, 22 Caolan Englefield, 23 Josiah Edwards-Giraud
Venue: The Rec
Kick-off: 17:30 BST
Where to watch: TNT Sports 1, TNT Sports Ultimate and Discovery+
Referee: Karl Dickson
Assistant Referees: Hamish Grant & Calum Howard
TMO: Dan Jones
Sunday
Harlequins v Saracens
Harlequins: 15 Tyrone Green, 14 Rodrigo Isgro, 13 Oscar Beard, 12 Jamie Benson, 11 Cadan Murley (c), 10 Marcus Smith, 9 Will Porter, 8 Chandler Cunningham-South, 7 Will Evans, 6 Jack Kenningham, 5 Kieran Treadwell, 4 Guido Petti, 3 Harry Williams, 2 Jack Walker, 1 Fin Baxter
Replacements: 16 George Turner, 17 Boris Wenger, 18 Pedro Delgado, 19 Jonny Green, 20 Zach Carr, 21 Alex Dombrandt, 22 Stu Townsend, 23 Sean Kerr
Saracens: 15 Max Malins, 14 Jack Bracken, 13 Nick Tompkins, 12 Owen Farrell, 11 Lucio Cinti, 10 Fergus Burke, 9 Ivan van Zyl (c), 8 Tom Willis, 7 Ben Earl, 6 Andy Onyeama-Christie, 5 Hugh Tizard, 4 Nick Isiekwe, 3 Marco Riccioni, 2 Theo Dan, 1 Rhys Carre
Replacements: 16 Jamie George, 17 Eroni Mawi, 18 Alec Clarey, 19 Harry Wilson, 20 Olamide Sodeke, 21 Juan Martin Gonzalez, 22 Charlie Bracken, 23 Brandon Jackson
Venue: The Stoop
Kick-off: 15:00 BST
Where to watch: TNT Sports 1, TNT Sports Ultimate and Discovery+
Referee: Adam Leal
Assitant Referees: Jonathan Cook & Jonathan Healy
TMO: Stuart Terheege