As the job cuts result in savings in future years, the NHS will be expected to recoup the costs further down the line.
Overall, government sources said no extra money is going into the NHS beyond what was agreed at the spending review this year – an extra £29bn a year above inflation by 2028-29.
In a speech to health managers at the NHS Providers’ conference in Manchester on Wednesday, Health Secretary Wes Streeting is expected to say: “I want to reassure taxpayers that every penny they are being asked to pay will be spent wisely.
“We’re now pushing down on the accelerator and slashing unnecessary bureaucracy, to reinvest the savings in frontline care.
“It won’t happen overnight, but with our investment and modernisation, we will rebuild our NHS so it is there for you when you need it once again.”
According to the government, the reforms will raise £1bn a year by the end of the parliament to improve services for patients.
It said every £1bn saved in bureaucracy costs is enough to fund an extra 116,000 hip and knee operations.
Chancellor Rachel Reeves is expected to make further announcements regarding the health service in the Budget on 26 November.