Retrieve is funded by NHS England South West and takes patients between hospitals in the South West that need specialist care.
It was set up to help patients access treatment not available in the hospital they were in.
The service launched in 2020 and then became a 24-hour service in 2024, following its busiest year ever.
That year, it moved to a new Bristol location near Aztec West.
It shares this base with SoNAR and WATCh, the neonatal and paediatric critical care transfer services.
The consultant-led team is made up of clinical staff and has its own vehicles and equipment, with bases in Bristol and Launceston in Cornwall.
Dr Scott Grier, clinical director for the service, said: “I am incredibly proud of everything our team has achieved over the past five years.
“We knew when we launched Retrieve would be a game-changing service for people in the South West and we have dramatically improved the care patients receive during transfer.
“As one of the first services to provide this kind of care to adult patients in England, we have led the way nationally and shown what can be achieved.
“We could not have done this without the support of our NHS England colleagues and our host UHBW.”
In the last year, Retrieve received more than 1,500 referrals and completed more than 1,200 transfers, which would previously have been undertaken by the regional 999 ambulance service.