Glioblastoma (cold tumor) kills roughly 12,000 Americans yearly; surgery, radiation, and chemotherapy barely dent survival odds. Repeat tumour injections demand repeated cranial surgery risking infection, bleeding and even stroke. Nasal drops eliminate that hellish cycle. Now, researchers at Washington University and Northwestern University have cracked a medical milestone—tiny nanostructures delivered via simple nasal drops can now travel directly into the brain and wake up the immune system to fight glioblastoma, one of the deadliest cancers.