The seven members of the Expedition 74 crew studied stem cells, packed up a cargo ship and maintained their toilet this week, Dec. 8-12, 2025, on board the International Space Station (ISS).

Orbital observation

Earth,’ I took a few shots right before going to bed. I think the amazing thing about the ISS is that you can see views like this without even trying,'” JAXA astronaut Kimiya Yui, an Expedition 74 flight engineer, wrote on social media on Thursday (Dec. 11).

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Yui’s photo nicely captures the “skies of blue and clouds of white” as sung by the iconic Louis Armstrong.

the blue waters and white clouds on Earth extend out to the curved horizon, set against the blackness space and in the foreground, components of a space station

Expedition 74 flight engineer Kimiya Yui, a JAXA astronaut, captured this view of Earth from the International Space Station on Thursday, Dec. 11, 2025. (Image credit: NASA / JAXA/Kimiya Yui)

microgravity as compared to on Earth.

Virtual — In a Roscosmos experiment that looks at how the vestibular system adapts to microgravity, Sergey Kud-Sverchkov and Sergei Mikaev traded off wearing a different set of VR (virtual reality) goggles to track their vision. The study could lead to developing additional countermeasures when readjusting to gravity.

Artemis missions to the moon and ultimately to Mars, JAXA astronaut Kimiya Yui installed and soundproofed the JEM Demonstration of CO2 Removal System in the station’s Kibo module. The experimental device traps carbon dioxide from the air and vents it overboard.

JAXA’s HTV-X1 — NASA astronauts Chris Williams and Mike Fincke, together with some help from Zena Cardman and JAXA astronaut Kimiya Yui, continued preparing the cargo ship for its departure in January. Williams worked on loading refuse and no-longer-needed equipment, while Fincke focused on preparing a science rack for its transfer from the space station to inside the HTV-X.

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Waste and Hygiene Compartment — Fincke also spent some of his time this week servicing one of the space station’s restrooms, replacing orbital plumbing components in the Tranquility node.

SpaceX‘s Dragon “Endeavour” attached to the space-facing port of the Harmony module and Roscosmos’ Soyuz MS-28 attached to the Earth-facing port of the Rassvet module.

There are four cargo spacecraft: Roscosmos’ Progress MS-31 (92P) docked to the space-facing port of the Poisk module, Progress MS-32 (93P) attached to the aft port of the Zvezda service module, Northrop Grumman’s Cygnus XL, the S.S. William C. “Willie” McCool, berthed to the Earth-facing common berthing mechanism (CBM) on the Unity node and Japan’s HTV-X1 attached to the Earth-facing CBM on the Harmony node.

As of Friday, the space station has been continuously crewed for 25 years, 1 month and 10 days.