NEED TO KNOW

  • Kris Jenner is getting candid about how she maintains her glow

  • The 70-year-old Kardashian-Jenner matriarch and momager admitted to trying Ozempic before it became popular

  • She ultimately decided the popular GLP-1 wasn’t right for her

Kris Jenner is sharing the “game changer” she switched to after Ozempic made her feel sick.

During a Tuesday, May 5 appearance on the SHE MD Podcast, the 70-year-old momager and businesswoman told hosts OBGYN Dr. Thais Aliabadi and women’s advocate Mary Alice Haney why the popular GLP-1 didn’t work for her.

“I did not do, like, an Ozempic,” Jenner said. “I tried it. We tried it once when no one knew what it was and it made me really sick.”

Kris Jenner attends the 2026 Met GalaCredit: Dimitrios Kambouris/Getty

Kris Jenner attends the 2026 Met Gala
Credit: Dimitrios Kambouris/Getty

Thinking back on the moment, Jenner said she told Aliabadi, “I can’t work anymore. I can’t. I’m so sick. I can’t, like nauseous. And so she goes, ‘Okay, okay. Let’s try something else.’”

Together, they “dialed around and looked at different options.”

Earlier in the conversation, the podcast hosts asked Jenner how she maintains her looks.

After explaining her history with the weight-loss drug that was originally used to improve blood sugar control in adults with type 2 diabetes and to lower the risk of major cardiovascular events, the mother of six shared what finally did work for her.

“I realized that a peptide injection was really great for me,” Jenner said. “And then I follow it up with supplements.”

Injectable peptides, or short chains of amino acids, have risen in popularity in recent years. The injections can be used to induce weight loss and improve athletic performance, among other purported benefits, according to the American Medical Association. Experts caution, though, that the effects of some of these peptides have not been studied extensively, and they may cause side effects ranging from stomach discomfort to pancreatitis.

The Kardashians star said Aliabadi advises her on which supplements to add to her diet, such as fish oils and omega-3s.

“And that was a game changer,” Jenner said. “That actually bought me an extra couple hours at night because I get up so early. I tend to want to go and collapse as soon as I have my last email or my last call or see my kids and have dinner and I’m done.”

She added that the peptides gave her more energy than she previously had, and that the supplements are also good for hair, nails and skin.

Jenner also acknowledged the impact of her “very famous” facelift, which went viral in 2025.

Kris Jenner on December 02, 2025 in Los AngelesCredit: Amy Sussman/Getty

Kris Jenner on December 02, 2025 in Los Angeles
Credit: Amy Sussman/Getty

“I had a very, well-known facelift a year ago. So that was helpful,” she said with a laugh, crediting Dr. Steven Levine for his work.

The Kardashian-Jenner matriarch recently addressed a report by RadarOnline that speculated she was allegedly “raging” about the results of her procedure just months after she debuted her refreshed look.

“Lately, it’s this headline about my facelift, which is really truly driving me crazy,” Jenner told her daughter Khloé Kardashian on the Khloé in Wonderland podcast in late April. “The headline right now is that I hate my facelift, and I’m really mad at — I’m furious at my doctor, Steven Levine, which couldn’t be further from the truth. It’s a flat-out lie. I love my facelift. I adore my doctor. I’m obsessed with him.”

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Jenner also said she normally doesn’t entertain rumors, but she decided to speak out because the stories were “really hurting someone else,” referencing Levine.

After her second facelift went viral last summer, she told Vogue Arabia in an August 2025 cover interview, “I decided to do this facelift because I want to be the best version of myself, and that makes me happy.”

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