The marathon will get under way at 09:00 BST on Sunday, with competitors in the half marathon setting off at 10:00 BST.
Alex Reeves will be among the racers taking part in the shorter – but still not short – half marathon.
The 28-year-old is fundraising for the Bradford charity Gig Buddies which supports adults with learning disabilities and autism in the district to have a full and varied social life.
“I am feeling a bit nervous, but excited at the same time. I did it last year and I was a lot less prepared,” he admits.
“I got inspired by Jamie Jones Buchanan from Leeds Rhinos.
“He was speaking at a work thing, basically saying you should always be trying to make a difference and I was like, ‘yes that is right, I am going to do that and I am going to try and raise some money’.”
As part of his volunteer role, Alex has buddied up with Harry Bowness.
Together, the pair go running, cycling, visiting the cinema or bowling.
“It gives you a chance to meet new people and go out and and explore different things,” Harry says.
The 25-year-old will cheering on his buddy Alex from the roadside during the race.
“I think he will smash it – I am chuffed,” he says.
“The more fundraising we can get, the more it expands the activities for other people who struggle with day-to-day lives.”