Some thiazide diuretics, such as hydrochlorothiazide, used to manage high blood pressure, reduce the amount of calcium your kidneys excrete. When combined with vitamin D (which increases calcium absorption), this can lead to hypercalcemia, or high blood calcium levels. Symptoms may include nausea, confusion, and kidney problems. If you’re taking both, doctors usually monitor calcium levels through blood tests to avoid complications. Never combine these without your doctor’s guidance, as adjusting the dose of either may be necessary to maintain balance.
