Tottenham, who beat Doncaster, will face the holders Newcastle away from home after Eddie Howe’s side made light-work of Bradford at St James’ Park. An eye-catching all-Welsh showdown will see Wrexham host Cardiff.
Liverpool and Crystal Palace, who meet in the Premier League this weekend, will do battle at Anfield for a place in the quarter-final after the Reds beat Championship side Southampton on Tuesday night.
Grimsby’s reward for a second round win over Manchester United and then beating beleaguered Sheffield Wednesday in round three is a home tie against Brentford.
Elsewhere, Swansea will host Manchester City and Fulham have been handed a tricky test against Wycombe away from home.
Fourth-round ties will take place the week commencing October 27.
Carabao Cup fourth round draw in full
Swansea vs Manchester City
Liverpool vs Crystal Palace