Oryza genome evolution through a tetraploid lens
Tanksley, S. D. & McCouch, S. R. Seed banks and molecular maps: unlocking genetic potential from the wild.…
Spatial transcriptomics identifies molecular niche dysregulation associated with distal lung remodeling in pulmonary fibrosis
Participants and samples The studies described here comply with ethical regulations as approved under local institutional review boards,…
Mutations in the small nuclear RNA gene RNU2-2 cause a severe neurodevelopmental disorder with prominent epilepsy
More than 4,000 genes have been established as etiological for a rare disease, of which only 69 are…
Pan-genome analysis reveals the evolution and diversity of Malus
The Malus evolutionary genomic landscape We sequenced accessions from 30 species, de novo assembled high-quality genomes and anchored…
Advances in single-cell DNA sequencing enable insights into human somatic mosaicism
Bizzotto, S. et al. Landmarks of human embryonic development inscribed in somatic mutations. Science 371, 1249–1253 (2021). Article …
Pan-genomic analysis highlights genes associated with agronomic traits and enhances genomics-assisted breeding in alfalfa
Annicchiarico, P., Barrett, B., Brummer, E. C., Julier, B. & Marshall, A. H. Achievements and challenges in improving…
Transcriptome-wide analysis of differential expression in perturbation atlases
Dixit, A. et al. Perturb-seq: dissecting molecular circuits with scalable single-cell RNA profiling of pooled genetic screens. Cell…
Genetic regulation of gene expression across multiple tissues in chickens
Hillier, L. W. & Miller, W. Sequence and comparative analysis of the chicken genome provide unique perspectives on…
The landscape of N6-methyladenosine in localized primary prostate cancer
The m6A landscape of localized prostate cancer We quantified the epitranscriptomes of 162 primary localized prostate tumors using…
Mapping genetic diversity with the GenomeIndia project – Nature
Mapping genetic diversity with the GenomeIndia project Nature A unique genome database of 10,000 ‘healthy’ Indians is ready for…