Searching for the origin of human brain tumours
The anatomical location and cell type from which tumours originate has biological, diagnostic and therapeutic implications, but understanding…
Genome synteny reveals hidden enhancer conservation
Long, H. K., Prescott, S. L. & Wysocka, J. Cell 167, 1170–1187 (2016). Article CAS PubMed PubMed Central …
Classification grid and evidence matrix for evaluating digital medical devices under the European union landscape
Definition of the scope of the grid The selected criteria included in the scope of the grid were…
Genomic landscape of multiple myeloma and its precursor conditions
The MM-like genomic score captures disease progression To characterize the somatic mutation landscape and drivers in precursor conditions…
Genome-wide association study of long COVID
Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland Vilma…
Workflow analysis and evaluation of a next-generation phenotyping tool: A qualitative study of Face2Gene
Artificial Intelligence in genetic medicine offers great potential for improving diagnosis and treatment. However, sustainable AI implementation in…
View of healthcare professionals on ultra-rapid genome sequencing and its future implementation in clinical practice for critically ill children
In the present study, which aimed to collect the views of those involved regarding urGS and its implementation,…
A crossroads in the timeline of human evolution
Ancient DNA (aDNA) sequencing is like unlocking a genetic time capsule, almost bringing the past back to life…
Investigating spatial gene circuits and gene–phenotype mechanisms with Perturb-FISH
Gene regulatory networks control functional phenotypes in cells and tissues. In complex tissues, these networks span cells and…
The contribution of gametic phase disequilibrium to the heritability of complex traits
Yang, J. et al. Common SNPs explain a large proportion of the heritability for human height. Nat. Genet.…