Transcriptome-wide analysis of differential expression in perturbation atlases
Dixit, A. et al. Perturb-seq: dissecting molecular circuits with scalable single-cell RNA profiling of pooled genetic screens. Cell…
Germany and Europe lead digital innovation and AI with collaborative health data use at continental level
Bienzeisler et al.1 show how federated access to 7.9 million data sets representing 2 million patients enables the…
Making cell therapy accessible: challenges and opportunities
Crystal Mackall: There are numerous bottlenecks. First, manufacturing of autologous products requires complex logistics wherein the product moves…
Genetic regulation of gene expression across multiple tissues in chickens
Hillier, L. W. & Miller, W. Sequence and comparative analysis of the chicken genome provide unique perspectives on…
Association between plausible genetic factors and weight loss from GLP1-RA and bariatric surgery
Ethics statement This study complies with all relevant ethical regulations and was conducted in accordance with the research…
Vascular Ehlers Danlos Syndrome and Chromosome 2q32 Microdeletion Syndrome
Glass I, Swindlehurst C, Aitken D, McCrea W, Boyd E. Interstitial deletion of the long arm of chromosome…
The landscape of N6-methyladenosine in localized primary prostate cancer
The m6A landscape of localized prostate cancer We quantified the epitranscriptomes of 162 primary localized prostate tumors using…
Mapping genetic diversity with the GenomeIndia project – Nature
Mapping genetic diversity with the GenomeIndia project Nature A unique genome database of 10,000 ‘healthy’ Indians is ready for…
Longitudinal single-cell multiomic atlas of high-risk neuroblastoma reveals chemotherapy-induced tumor microenvironment rewiring
Single-cell longitudinal profiling reveals microenvironmental shifts We profiled neuroblastoma samples from 22 patients with high-risk neuroblastoma obtained through…
Leveraging genetics to understand ADAR1-mediated RNA editing in health and disease
Crick, F. Molecular biology in the year 2000. Nature 228, 613–615 (1970). Article CAS PubMed Google Scholar Crick,…