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Browsing Tag

Computational biology and bioinformatics

12 posts
SScience
can it produce the next big breakthrough?
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can it produce the next big breakthrough?

  • 18 November 2025
No one could accuse Demis Hassabis of dreaming small. In 2016, the company he co-founded, DeepMind, shocked the…
HHealthcare
Reporting guidelines for studies involving generative artificial intelligence applications: what do I use, and when?
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Reporting guidelines for studies involving generative artificial intelligence applications: what do I use, and when?

  • 9 November 2025
The rise in publications addressing the use of general artificial intelligence (GAI), namely large language models (LLMs), for…
SScience
Loss of macroevolutionary species fitness explains the rise and fall of clades
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Loss of macroevolutionary species fitness explains the rise and fall of clades

  • 18 October 2025
Raup, D. M. Biological extinction in Earth history. Science 231, 1528–1533 (1986). Article  CAS  PubMed  Google Scholar  Benton,…
GGenetics
Spatial architecture of development and disease
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Spatial architecture of development and disease

  • 1 October 2025
Bressan, D., Battistoni, G. & Hannon, G. J. The dawn of spatial omics. Science 381, eabq4964 (2023). Article …
SScience
The Biodiversity Cell Atlas: mapping the tree of life at cellular resolution
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The Biodiversity Cell Atlas: mapping the tree of life at cellular resolution

  • 24 September 2025
Goffeau, A. et al. Life with 6000 genes. Science 274, 546–567 (1996). Article  ADS  CAS  PubMed  Google Scholar …
GGenetics
CRISPR-GPT for agentic automation of gene-editing experiments
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CRISPR-GPT for agentic automation of gene-editing experiments

  • 17 August 2025
Building AI co-pilot harnessing LLM’s reasoning ability CRISPR-GPT supports four major gene-editing modalities and 22 gene-editing experiment tasks…
GGenetics
Predicting resistance to chemotherapy using chromosomal instability signatures
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Predicting resistance to chemotherapy using chromosomal instability signatures

  • 28 June 2025
CIN signatures as biomarkers of chemotherapy resistance The presence of CIN in a tumor has long been recognized…
GGenetics
Human subcutaneous and visceral adipocyte atlases uncover classical and nonclassical adipocytes and depot-specific patterns
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Human subcutaneous and visceral adipocyte atlases uncover classical and nonclassical adipocytes and depot-specific patterns

  • 4 May 2025
Human fat depot-specific adipocyte atlases To generate hSAT and hVAT depot-specific human adipocyte atlases, we performed single-nucleus RNA…
GGenetics
Transcriptome-wide analysis of differential expression in perturbation atlases
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Transcriptome-wide analysis of differential expression in perturbation atlases

  • 21 April 2025
Dixit, A. et al. Perturb-seq: dissecting molecular circuits with scalable single-cell RNA profiling of pooled genetic screens. Cell…
GGermany
Germany and Europe lead digital innovation and AI with collaborative health data use at continental level
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Germany and Europe lead digital innovation and AI with collaborative health data use at continental level

  • 21 April 2025
Bienzeisler et al.1 show how federated access to 7.9 million data sets representing 2 million patients enables the…
United Kingdom
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