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Browsing Tag

Epigenomics

4 posts
GGenetics
Single-cell Micro-C profiles 3D genome structures at high resolution and characterizes multi-enhancer hubs
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Single-cell Micro-C profiles 3D genome structures at high resolution and characterizes multi-enhancer hubs

  • 7 July 2025
Development of scMicro-C The previously reported bulk Micro-C chemistry, although offering nucleosome-level contact maps, cannot be applied to…
GGenetics
Genome synteny reveals hidden enhancer conservation
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Genome synteny reveals hidden enhancer conservation

  • 27 May 2025
Long, H. K., Prescott, S. L. & Wysocka, J. Cell 167, 1170–1187 (2016). Article  CAS  PubMed  PubMed Central …
GGenetics
Three-dimensional genome landscape of primary human cancers
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Three-dimensional genome landscape of primary human cancers

  • 12 May 2025
Multiple scales of 3D genome organization in human cancers We profiled genome-wide chromosome conformation in 69 tumor samples…
GGenetics
Longitudinal single-cell multiomic atlas of high-risk neuroblastoma reveals chemotherapy-induced tumor microenvironment rewiring
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Longitudinal single-cell multiomic atlas of high-risk neuroblastoma reveals chemotherapy-induced tumor microenvironment rewiring

  • 15 April 2025
Single-cell longitudinal profiling reveals microenvironmental shifts We profiled neuroblastoma samples from 22 patients with high-risk neuroblastoma obtained through…
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