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Browsing Tag

Functional genomics

7 posts
SScience
The Biodiversity Cell Atlas: mapping the tree of life at cellular resolution
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The Biodiversity Cell Atlas: mapping the tree of life at cellular resolution

  • 24 September 2025
Goffeau, A. et al. Life with 6000 genes. Science 274, 546–567 (1996). Article  ADS  CAS  PubMed  Google Scholar …
GGenetics
Fueling chromosomal gene diversification and artificial evolution with CRISPR | Genome Biology
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Fueling chromosomal gene diversification and artificial evolution with CRISPR | Genome Biology

  • 24 September 2025
Wilson DS, Keefe AD. Random mutagenesis by PCR. Curr Protoc Mol Biol. 2001;51:8–3. Google Scholar  Reetz MT, Wu…
GGenetics
Single-nucleus chromatin accessibility profiling identifies cell types and functional variants contributing to major depression
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Single-nucleus chromatin accessibility profiling identifies cell types and functional variants contributing to major depression

  • 21 September 2025
James, S. L. et al. Global, regional, and national incidence, prevalence, and years lived with disability for 354…
GGenetics
Clarifying Uncertain Genetic Tests in Cancer Treatment
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Clarifying Uncertain Genetic Tests in Cancer Treatment

  • 6 September 2025
Cancer treatment is becoming more personalised. By considering a patient’s unique genetic and molecular profile, along with their…
GGenetics
Methods and applications of in vivo CRISPR screening
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Methods and applications of in vivo CRISPR screening

  • 30 July 2025
Auton, A. et al. A global reference for human genetic variation. Nature 526, 68–74 (2015). Google Scholar  García-García,…
GGenetics
Precisely defining disease variant effects in CRISPR-edited single cells
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Precisely defining disease variant effects in CRISPR-edited single cells

  • 23 July 2025
Cell-line cultures and genomic editing HH cutaneous T cell lines (ATCC, CRL-2105), Jurkat E6-1 (ATCC, TIB-152) and Daudi…
GGenetics
Genetics of circulating proteins in newborn babies at high risk of type 1 diabetes
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Genetics of circulating proteins in newborn babies at high risk of type 1 diabetes

  • 22 April 2025
Ethics The study (GPPAD dried blood spot omics to predict health and autoimmunity outcomes in children) was approved…
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