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Browsing Tag

Gene Function

84 posts
HHealthcare
Translating genomic data into healthcare practice with the Singapore National Precision Medicine program
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Translating genomic data into healthcare practice with the Singapore National Precision Medicine program

  • 29 July 2026
Precision Health Research, Singapore (PRECISE), Singapore, Singapore Shih Wee Seow, Clement Qiwen Sin, Denise Xin Yi Chua, Emily Shu Fang Lau, Gloria…
SScience
SUMOylation enhances DNMT1 function to repress mega-intergenic RNAs and viral mimicry
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SUMOylation enhances DNMT1 function to repress mega-intergenic RNAs and viral mimicry

  • 22 July 2026
Bostick, M. et al. UHRF1 plays a role in maintaining DNA methylation in mammalian cells. Science 317, 1760–1764…
HHealth
Genome-wide association analyses of borderline personality disorder identify 11 loci and highlight shared risk with mental and somatic disorders
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Genome-wide association analyses of borderline personality disorder identify 11 loci and highlight shared risk with mental and somatic disorders

  • 21 July 2026
Hector Institute for Artificial Intelligence in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim,…
HHealth
A blended genome and exome sequencing method captures genetic variation in an unbiased and cost-effective manner
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A blended genome and exome sequencing method captures genetic variation in an unbiased and cost-effective manner

  • 9 July 2026
Ethics approval and consent to participate All cohorts involving human participants that were included in this research have…
SScience
Identifying critical lysines in mammalian histone H3 with high-throughput CRISPR prime editing
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Identifying critical lysines in mammalian histone H3 with high-throughput CRISPR prime editing

  • 8 July 2026
Adapting prime editing for mammalian histone mutagenesis Mouse canonical histone H3 is encoded by nine H3.1 and three…
HHealthcare
The promise of adaptive health in the United Arab Emirates and beyond
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The promise of adaptive health in the United Arab Emirates and beyond

  • 6 June 2026
Department of Medicine, Johns Hopkins University, Baltimore, MD, USA Andrew P. Feinberg Department of Biomedical Engineering, Johns Hopkins…
SScience
De novo formation of cis-regulatory contacts in the absence of NIPBL-driven chromatin loop extrusion
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De novo formation of cis-regulatory contacts in the absence of NIPBL-driven chromatin loop extrusion

  • 14 April 2026
Vermunt, M. W., Zhang, D. & Blobel, G. A. The interdependence of gene-regulatory elements and the 3D genome.…
HHealth
Biallelic variants in RNU2-2 cause the most prevalent known recessive neurodevelopmental disorder
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Biallelic variants in RNU2-2 cause the most prevalent known recessive neurodevelopmental disorder

  • 31 March 2026
Genetic association analysis We identified the recessive form of RNU2-2 syndrome through a joint statistical analysis of the…
SScience
Three-dimensional genome reorganization foreshadows zygotic genome activation in Drosophila
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Three-dimensional genome reorganization foreshadows zygotic genome activation in Drosophila

  • 26 February 2026
Drosophila stock maintenance PCNA::EGFP flies used for interphase-staged Pico-C were generously provided by S. A. Blythe and E.…
GGenetics
Redefining cellular reprogramming with advanced genomic technologies
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Redefining cellular reprogramming with advanced genomic technologies

  • 18 October 2025
Briggs, R. & King, T. J. Transplantation of living nuclei from blastula cells into enucleated Frogs’ eggs. Proc.…
United Kingdom
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