Using large-scale population-based data to improve disease risk assessment of clinical variants
Turro, E. et al. Whole-genome sequencing of patients with rare diseases in a national health system. Nature 583,…
Exploring the genetic intersection between obesity-associated genetic variants and insulin sensitivity indices
Previous large-scale GWAS studies have independently identified numerous genetic variants associated with the obesity-related traits such as BMI…
Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk
Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA Seung Hoan Choi, Sean J. Jurgens, Ling Xiao, Matthew…