Mapping vulnerability or resilience in Alzheimer’s through imaging and genetics
It’s been recognized for some time that Alzheimer’s disease affects brain regions differently and that tau – a…
Joseph L. Goldstein: Unraveling the Genetic Code of Cholesterol
Joseph L. Goldstein is a pioneering American physician and geneticist whose work in cholesterol metabolism has left an…
First large-scale stem cell bank created to investigate Alzheimer’s genetic risk factors
Alzheimer’s disease (AD) is a common, debilitating neurodegenerative disease affecting about 10 percent of people over the age…
Gene therapy brings back hearing in young and adult deaf patients
Gene therapy can improve hearing in children and adults with congenital deafness or severe hearing impairment, a new…
Scientists reveal how chemotherapy causes genetic damage in healthy blood
For the first time, scientists have systematically studied the genetic effects of chemotherapy on healthy tissues. Researchers from…
Healthy lifestyle lowers risk of diverticulitis despite genetic susceptibility
Maintaining a healthy lifestyle-specifically, a diet rich in fibre but light on red/processed meat, regular exercise, not smoking,…
Genetic bottlenecks limit the rise of pandemic cholera strains
A new study by the Genomics and Microbial Evolution Group at the Miguel Hernández University of Elche (UMH)…
Comprehensive study maps genetic mutations in SLC13A5 linked to epilepsy
Citrate is essential for the metabolism and development of neurons. A membrane transport protein called SLC13A5 plays a…
Expanding the genetic code in mammalian cells using pseudouridine modified codons
To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers…
Discovery of a genetic dimmer switch controlling embryonic development
A team of scientists at the MRC Laboratory of Medical Sciences (LMS) has uncovered a previously unknown mechanism…