Tiny fish could unlock new MS drugs. Brexit is getting in the way. – POLITICO
Tiny fish could unlock new MS drugs. Brexit is getting in the way. – POLITICO Skip to main…
Low carbohydrate high fat diet curbs glioblastoma by shifting lipids and limiting cancer stem cell metabolic flexibility
Metabolic rewiring fuels tumorigenicity of cancer stem cells contributing to universal glioblastoma (GBM) recurrence. Invasive glioblastoma stem cells…
Distinct brain regions mediate regulation of food intake in response to GIPR agonism or antagonism
Dual agonism of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors (GLP-1R and GIPR, respectively), in the…
BIOSECURE Act for UK and EU life sciences companies: navigating China–US contracting risks, James Johnston, Claire Smith
The global biotech market is moving along two conflicting paths. On the one hand, Western pharmaceutical companies are…
Genetic trade-offs in fertility and longevity explain the maintenance of disease-associated alleles in humans
Welter, D. et al. The NHGRI GWAS Catalog, a curated resource of SNP-trait associations. Nucleic Acids Res. 42,…
Rates of passerine body plan evolution in time and space
Jablonski, D., Roy, K. & Valentine, J. W. Out of the tropics: evolutionary dynamics of the latitudinal diversity…
Spatial mapping and senolytic targeting of senescent and disease-associated microglia in aged mouse brain white matter
Expression of DAM and senescence genes, including p16 ink4a and Lgals3, increase in aged brain white matter We…
AHMM gets approval for Hammersmith hotel and office scheme
The scheme was given the green light by a unanimous vote at Hammersmith and Fulham Council’s planning committee…
A data-driven framework reconstructs the molecular continuum of human MASLD progression
Transcriptomics-based disease trajectory analysis captures MASLD progression We first sought to determine whether MASLD progression could be represented…
Common and rare genetic variant associations with cognitive performance across development in British birth cohorts
This work complies with all relevant ethics regulations. The Cambridge South Research Ethics Committee (10/H0305/83), The Republic of…