Twenty years of progress in human exercise metabolism research
Hawley, J. A., Hargreaves, M., Joyner, M. J. & Zierath, J. R. Integrative biology of exercise. Cell 159,…
Clinical features and genetic analysis of A20 haploinsufficiency | Orphanet Journal of Rare Diseases
The A20 acts as a critical negative regulator of the NF-κB signaling pathway by suppressing inflammatory cascades through…
Association of SARS-CoV-2 vaccination status with risk of influenza-like illness and loss of workdays in healthcare workers
Setting and participants In our prospective multicentre HCW cohort, participants were recruited from nine healthcare networks in Northern…
Trends in fetal autopsy and placental histopathology following stillbirth, United States, 2014–2023
Stillbirth affects approximately 1 in 175 births in the United States, totaling approximately 21,000 births each year [1].…
Bridging psychiatry and rare genetic diseases: a scoping review of therapeutic strategies and diagnostic delay paired with healthcare economic burden analysis | Orphanet Journal of Rare Diseases
Nguengang Wakap S, Lambert DM, Olry A, Rodwell C, Gueydan C, Lanneau V, Murphy D, Le Cam Y,…
A consensus statement on the use of digital twins in medicine
The DT is a generic instrument able to integrate different technologies applicable across the disease (and indeed health)…
Sociodemographic factors associated with health-related quality of life in UK healthcare workers: a cross-sectional study | BMC Medicine
ONS: International migration and the healthcare workforce Office for National Statistics. Office for National Statistics. 2019. Available from:…
Targeted in vivo gene integration of a secretion-enabled GLP-1 receptor agonist reverses diet-induced non-genetic obesity and pre-diabetes
Plasmid construction The Exe4 gene was codon-optimized using the GeneSmart codon optimization tool (https://www.genscript.com/gensmart-free-gene-codon-optimization.html) based on the amino…
A mixed methods formative evaluation of the United Kingdom National Health Service Artificial Intelligence Lab
We interviewed 85 individuals, reviewed 1021 documents, and conducted 12 observations. A detailed description of the dataset is…
Cognitive bias in clinical large language models
Biases affecting clinical LLM systems can arise at multiple stages, including data-related biases from collection and representation, model-related…