DiffInvex identifies key genes driving chemotherapy resistance
Just as species adapt over generations, our body’s cells accumulate DNA changes throughout life. Most are harmless, yet…
Advances in single-cell DNA sequencing enable insights into human somatic mosaicism
Bizzotto, S. et al. Landmarks of human embryonic development inscribed in somatic mutations. Science 371, 1249–1253 (2021). Article …
Transitioning pancreatic cells show lasting epigenetic cancer traits
Johns Hopkins Medicine scientists say they have found a pattern of so-called epigenetic “marks” in a transition state…