Bridging continuous and discrete evolution through a controllable, hypermutagenic phage-bacteria system
General methods All E. coli and phage strains created in this study are listed in Supplementary Table 1,…
Nuclease–NTPase antiphage defence systems use conserved molecular features to control bacterial immunity
Roberts, R. J. et al. A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes. Nucleic…
Heart-nosed bat alphacoronaviruses use human CEACAM6 to enter cells
Ethics statement The use of human sera for this study was approved by the Scientific and Ethics Review…
Plasmids promote antimicrobial resistance through insertion sequence-mediated gene inactivation
Ho, C. S. et al. Antimicrobial resistance: a concise update. Lancet Microbe 6, 100947 (2025). Article PubMed Google…
what we do and don’t know
We are 23 of the 27 original members of the Scientific Advisory Group for the Origins of Novel…
This giant virus hijacks cells’ protein-making machinery to multiply wildly
Acanthamoeba polyphaga mimivirus (artist’s impression) is a giant among viruses, both in physical size and because of the…
Large-scale analysis of bacterial genomes reveals thousands of lytic phages
Identification of lytic phages in bacterial assemblies To identify complete lytic bacteriophage genome sequences within bacterial genome assemblies…
STREAMS guidelines: standards for technical reporting in environmental and host-associated microbiome studies
New Mexico Consortium, Los Alamos, NM, USA Julia M. Kelliher Department of Microbiology, Genetics, and Immunology, Michigan State…
virologist whose enzyme discovery transformed understanding of cancer and HIV/AIDS
Credit: Christopher Michel (CC-BY-SA-4.0) The world has lost a giant of virology, molecular biology and science advocacy with…
Genome sequencing for prevention of health-care-associated bacterial infections
WHO Team Infection Prevention and Control (IPC). Global report on infection prevention and control. WHO https://www.who.int/publications/i/item/9789240051164 (2022). Warren,…