Mobile genetic elements shape microbial diversity and functions in thawing permafrost soils
Data collection, metagenome assembly and binning, gene annotation and taxonomy assignment Our study site, Stordalen Mire, is a…
Complex multicellularity is linked with expanded specialized metabolite production in microorganisms
Fischbach, M. A., Walsh, C. T. & Clardy, J. The evolution of gene collectives: how natural selection drives…
Purine bias in bacterial genes is driven by runaway transcription
Strains B. subtilis strains were generated from 168 (bearing the trpC2 mutation), and E. coli genomic DNA was…
Next-generation probiotics: an outlook into current applications and future developments
Hill, C. et al. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and…
Bridging continuous and discrete evolution through a controllable, hypermutagenic phage-bacteria system
General methods All E. coli and phage strains created in this study are listed in Supplementary Table 1,…
Nuclease–NTPase antiphage defence systems use conserved molecular features to control bacterial immunity
Roberts, R. J. et al. A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes. Nucleic…
Heart-nosed bat alphacoronaviruses use human CEACAM6 to enter cells
Ethics statement The use of human sera for this study was approved by the Scientific and Ethics Review…
Plasmids promote antimicrobial resistance through insertion sequence-mediated gene inactivation
Ho, C. S. et al. Antimicrobial resistance: a concise update. Lancet Microbe 6, 100947 (2025). Article PubMed Google…
what we do and don’t know
We are 23 of the 27 original members of the Scientific Advisory Group for the Origins of Novel…
This giant virus hijacks cells’ protein-making machinery to multiply wildly
Acanthamoeba polyphaga mimivirus (artist’s impression) is a giant among viruses, both in physical size and because of the…