{"id":100161,"date":"2025-05-14T07:11:08","date_gmt":"2025-05-14T07:11:08","guid":{"rendered":"https:\/\/www.europesays.com\/uk\/100161\/"},"modified":"2025-05-14T07:11:08","modified_gmt":"2025-05-14T07:11:08","slug":"genetic-saliva-test-improves-ivf-success-personalised-hormone-therapy-reduces-side-effects","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/uk\/100161\/","title":{"rendered":"Genetic saliva test improves IVF success personalised hormone therapy reduces side effects"},"content":{"rendered":"<p>A simple saliva test can help improve the chances of IVF, according to a new study by Swedish researchers.<\/p>\n<p>The findings, published in peer-reviewed <a href=\"https:\/\/www.frontiersin.org\/journals\/endocrinology\/articles\/10.3389\/fendo.2025.1576090\/full\" target=\"_blank\" rel=\"nofollow noopener\">Frontiers in Endocrinology<\/a>, has found that a genetic test could reduce harmful side effects for women undergoing fertility procedures.<\/p>\n<p>Led by Yvonne Lundberg Giwercman from Lund University, the research highlights how personalised hormone therapy, based on a woman\u2019s genetic makeup, can lead to more successful pregnancies.<\/p>\n<p>About 15% of couples of reproductive age struggle with infertility. A growing number of people are <a href=\"https:\/\/www.indiatoday.in\/health\/story\/world-first-baby-has-been-born-using-ai-assisted-ivf-system-2706867-2025-04-10\" target=\"_blank\" rel=\"noopener\">postponing parenthood<\/a>, leading to a sharp increase in assisted reproduction methods like IVF.<\/p>\n<p>However, IVF treatments come with challenges. The procedure involves hormone therapy to stimulate egg production, but nearly 75% of IVF attempts fail.<\/p>\n<p>Up to 20% of women experience side effects, <a href=\"https:\/\/www.indiatoday.in\/world\/us-news\/story\/georgia-woman-sues-fertility-clinic-after-giving-birth-to-another-couples-baby-in-ivf-nightmare-glbs-2682593-2025-02-19\" target=\"_blank\" rel=\"noopener\">some requiring emergency care<\/a>.<\/p>\n<p>\u201cA major issue is that doctors currently have to guess which hormone treatment is best for each woman,\u201d said Ida Hjelmr, the study\u2019s first author and a laboratory researcher at Lund University.<\/p>\n<p>To find a solution, <a href=\"https:\/\/www.indiatoday.in\/health\/story\/at-46-type-1-diabetes-woman-gives-birth-to-triplets-ivf-survive-without-complications-2707035-2025-04-10\" target=\"_blank\" rel=\"noopener\">the team analysed the genes<\/a> of 1,466 women undergoing IVF.<\/p>\n<p>They discovered that women with a specific version of the FSH receptor gene responded better to biological hormones, while others did better with synthetic hormones.<\/p>\n<p>By matching treatment to genetic type, success rates improved significantly.<\/p>\n<p>\u201cWe saw a 38% increase in births among women who received hormone therapy that matched their gene variation. That\u2019s 110 more babies for every 1,000 women treated,\u201d said Giwercman.<\/p>\n<p>To make this process faster and more accessible, the team <a href=\"https:\/\/www.indiatoday.in\/india\/story\/india-rushes-ivf-clinics-drop-in-fertility-rate-what-factor-responsible-decline-2571647-2024-07-25\" target=\"_blank\" rel=\"noopener\">developed a simple oral swab test<\/a> that shows the ideal hormone treatment within an hour, visible as a pink or yellow result.<\/p>\n<p>The test is expected to be available by early 2026, said Giwercman, who is also the CEO of the company that developed the oral swab test.<\/p>\n<p>The researchers have applied for a patent and launched a company, Dx4Life AB, to bring the product to market.<\/p>\n<p>They hope the test will lead to more successful IVF outcomes while reducing health risks and healthcare costs.<\/p>\n<p>Published By: <\/p>\n<p>Daphne Clarance<\/p>\n<p>Published On: <\/p>\n<p>May 14, 2025<\/p>\n","protected":false},"excerpt":{"rendered":"A simple saliva test can help improve the chances of IVF, according to a new study by Swedish&hellip;\n","protected":false},"author":2,"featured_media":100162,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3846],"tags":[46506,46508,46505,46504,46502,267,12516,3396,46509,46503,41938,70,46507,16,15],"class_list":{"0":"post-100161","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-genetics","8":"tag-assisted-reproduction","9":"tag-dx4life-ab","10":"tag-fertility-treatment","11":"tag-fsh-receptor-gene","12":"tag-genetic-test","13":"tag-genetics","14":"tag-infertility","15":"tag-ivf","16":"tag-ivf-saliva-test-swedish-study","17":"tag-personalised-hormone-therapy-study","18":"tag-saliva-test","19":"tag-science","20":"tag-swedish-study","21":"tag-uk","22":"tag-united-kingdom"},"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@uk\/114504945758938248","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts\/100161","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/comments?post=100161"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts\/100161\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/media\/100162"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/media?parent=100161"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/categories?post=100161"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/tags?post=100161"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}