{"id":125127,"date":"2025-05-23T11:32:09","date_gmt":"2025-05-23T11:32:09","guid":{"rendered":"https:\/\/www.europesays.com\/uk\/125127\/"},"modified":"2025-05-23T11:32:09","modified_gmt":"2025-05-23T11:32:09","slug":"unraveling-the-genetic-mystery-of-autism","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/uk\/125127\/","title":{"rendered":"Unraveling the genetic mystery of autism"},"content":{"rendered":"<p class=\"sc-9a00e533-0 hxuGS\">Until the 1970s, the prevailing belief in psychiatry was that autism was a consequence of bad parenting. In the 1940s, the Austrian psychiatrist Leo Kanner had coined the\u00a0<a class=\"sc-f9178328-0 bGFWdi\" href=\"https:\/\/muse.jhu.edu\/article\/740316\" target=\"_blank\" rel=\"noopener\">controversial \u201crefrigerator mother\u201d theory<\/a>\u00a0suggesting that autism arose from early childhood trauma, created by mothers who were cold, uncaring and rejected their children.<\/p>\n<p class=\"sc-9a00e533-0 hxuGS\">[I]t was not until 1977, when a couple of psychiatrists carried out <a class=\"sc-f9178328-0 bGFWdi\" href=\"https:\/\/acamh.onlinelibrary.wiley.com\/doi\/10.1111\/j.1469-7610.1977.tb00443.x\" target=\"_blank\" rel=\"noopener\">a landmark study<\/a>\u00a0demonstrating that autism often runs in identical twins, that a more nuanced and accurate picture of autism\u2019s origins began to emerge.<\/p>\n<p>Follow the latest news and policy debates on sustainable agriculture, biomedicine, and other \u2018disruptive\u2019 innovations. Subscribe to our newsletter.<\/p>\n<p>[A] variety of <a class=\"sc-f9178328-0 bGFWdi\" href=\"https:\/\/clinicaltrials.gov\/study\/NCT06662188?term=Jaguar%20Gene%20Therapy&amp;rank=1\" target=\"_blank\" rel=\"noopener\">clinical trials<\/a>\u00a0have begun, all using various therapeutic strategies to try and\u00a0<a class=\"sc-f9178328-0 bGFWdi\" href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10886956\/\" target=\"_blank\" rel=\"noopener\">target the single genes<\/a> underpinning physical and intellectual disability in different individuals with profound autism.<\/p>\n","protected":false},"excerpt":{"rendered":"Until the 1970s, the prevailing belief in psychiatry was that autism was a consequence of bad parenting. In&hellip;\n","protected":false},"author":2,"featured_media":125128,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3846],"tags":[267,70,16,15],"class_list":{"0":"post-125127","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-genetics","8":"tag-genetics","9":"tag-science","10":"tag-uk","11":"tag-united-kingdom"},"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@uk\/114556930978959805","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts\/125127","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/comments?post=125127"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts\/125127\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/media\/125128"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/media?parent=125127"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/categories?post=125127"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/tags?post=125127"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}