{"id":178163,"date":"2025-06-12T10:33:11","date_gmt":"2025-06-12T10:33:11","guid":{"rendered":"https:\/\/www.europesays.com\/uk\/178163\/"},"modified":"2025-06-12T10:33:11","modified_gmt":"2025-06-12T10:33:11","slug":"key-eating-habit-of-centenarians-revealed","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/uk\/178163\/","title":{"rendered":"Key eating habit of centenarians revealed"},"content":{"rendered":"<p>Scientists have uncovered why residents of Acciaroli, a picturesque town in Italy&#8217;s Cilento-Salerno region, routinely live past 100 in remarkable health. <\/p>\n<p>The decade-long Cilento Initiative on Aging Outcomes (CIAO) study has revealed extraordinary findings about the area&#8217;s roughly 300 centenarians.<\/p>\n<p>&#8220;The centenarians of the CIAO study are remarkably robust and healthy, and can be found here in numbers per capita greater than most places on Earth,&#8221; said Salvatore Di Somma, MD, the study&#8217;s lead Italian investigator and founder of Great Health Science.<\/p>\n<p>The research, which began in 2015, has employed cutting-edge biomedical techniques to understand what drives their exceptional longevity and how these discoveries might help others achieve similar health outcomes.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" id=\"62890\" data-rm-shortcode-id=\"3070b979053e15c6b5fcc6092f1640e5\" data-rm-shortcode-name=\"rebelmouse-image\" class=\"rm-shortcode rm-lazyloadable-image \" lazy-loadable=\"true\" src=\"data:image\/svg+xml,%3Csvg%20xmlns='http:\/\/www.w3.org\/2000\/svg'%20viewBox='0%200%201200%20800'%3E%3C\/svg%3E\" data-runner-src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2025\/06\/centenarians.jpg\" width=\"1200\" height=\"800\" alt=\"centenarians\"\/><\/p>\n<p>Most centenarians in the village share the same habits<\/p>\n<p>GETTY<\/p>\n<p>The groundbreaking research has revealed that these centenarians are biologically 8.3 years younger than their chronological age, based on analysis of 24 key blood metabolite measurements. <\/p>\n<p>Scientists assessed 128 centenarians and 50 controls, finding that 2,812 of the 32,514 metabolites measured differed significantly in the long-lived residents.<\/p>\n<p>Past studies have shown that they enjoy robust blood circulation that is comparable in efficiency to people 30 years younger. <\/p>\n<p>They also display low blood levels of adrenomedullin (bio-ADM), a peptide hormone that regulates blood pressure and maintains vascular integrity.<\/p>\n<p>&#8220;Low levels of bio-ADM is considered an indicator of good vascular microcirculation, and good microcirculation is an indicator for increased longevity,&#8221; researchers noted.<\/p>\n<p>An impressive 90 per cent of these centenarians follow the Mediterranean diet, characterised by abundant fresh fruits, vegetables, whole grains, legumes, nuts and olive oil, whilst consuming red meat only sparingly.<\/p>\n<p>&#8220;The Mediterranean diet is not a meal plan. It&#8217;s not a fad,&#8221; said Di Somma. &#8220;It&#8217;s a way of life.&#8221;<\/p>\n<p>Analysis of olive oil produced in the Cilento region revealed it to be low in fatty acids and compounds associated with increased risk of heart disease or accelerated brain decline.<\/p>\n<p>Additionally, most centenarians maintained regular physical activity and remained socially engaged with friends and family. <\/p>\n<p>This combination of diet and lifestyle factors appears to deliver significant health dividends both short and long-term.<\/p>\n<p>The centenarians exhibited notably coordinated immune activation and cytokine regulation in their T-cells and macrophages. <\/p>\n<p>They showed elevated antiviral and inflammatory programmes, alongside greater communication among immune response cells.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" id=\"f2c77\" data-rm-shortcode-id=\"2457eac5291e00280d52435563d94607\" data-rm-shortcode-name=\"rebelmouse-image\" class=\"rm-shortcode rm-lazyloadable-image \" lazy-loadable=\"true\" src=\"data:image\/svg+xml,%3Csvg%20xmlns='http:\/\/www.w3.org\/2000\/svg'%20viewBox='0%200%205862%203908'%3E%3C\/svg%3E\" data-runner-src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2025\/06\/mediterrean-food.jpg\" width=\"5862\" height=\"3908\" alt=\"mediterrean  food\"\/><\/p>\n<p>90% of the centenarians in Acciaroli follow the Mediterranean diet<\/p>\n<p>GETTY<\/p>\n<p>&#8220;Our initial hypothesis was that centenarians have increased inflammatory mediators, which are expected to increase with ageing,&#8221; said David Brenner, MD, president and CEO of Sanford Burnham Prebys. <\/p>\n<p>&#8220;However, the centenarians also have increased anti-inflammatory mediators, which may protect the centenarians from inflammation and tissue injury.&#8221;<\/p>\n<p>A pilot study in Australia demonstrated that following a Mediterranean diet and lifestyle checklist led to significant health improvements, suggesting these findings could help others achieve similar longevity through dietary and lifestyle modifications.<\/p>\n","protected":false},"excerpt":{"rendered":"Scientists have uncovered why residents of Acciaroli, a picturesque town in Italy&#8217;s Cilento-Salerno region, routinely live past 100&hellip;\n","protected":false},"author":2,"featured_media":178164,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4318],"tags":[105,4716,12,4434,512,16,15],"class_list":{"0":"post-178163","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-nutrition","8":"tag-health","9":"tag-longevity","10":"tag-news","11":"tag-nutrition","12":"tag-sgg","13":"tag-uk","14":"tag-united-kingdom"},"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@uk\/114669945143987990","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts\/178163","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/comments?post=178163"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts\/178163\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/media\/178164"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/media?parent=178163"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/categories?post=178163"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/tags?post=178163"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}