{"id":243870,"date":"2025-07-06T23:37:17","date_gmt":"2025-07-06T23:37:17","guid":{"rendered":"https:\/\/www.europesays.com\/uk\/243870\/"},"modified":"2025-07-06T23:37:17","modified_gmt":"2025-07-06T23:37:17","slug":"gene-found-to-link-obesity-risk-in-labradors-and-humans-2","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/uk\/243870\/","title":{"rendered":"Gene found to link obesity risk in labradors and humans"},"content":{"rendered":"<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">&#8220;By studying dogs, we&#8217;ve honed in on some interesting new biology here,&#8221; explained lead researcher Dr Eleanor Raffan from the University of Cambridge&#8217;s department of physiology, development and neuroscience. <\/p>\n<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">She added that the discovery showed that &#8220;owners of slim dogs are not morally superior &#8211; and the same is true of slim people&#8221;.  <\/p>\n<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">&#8220;If you have a high genetic risk of obesity, you&#8217;re prone to gaining weight unless you put a huge effort into not doing so. And those with low genetic risk just don&#8217;t have to work so hard.&#8221;<\/p>\n<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">This canine-human biological link came from the researchers&#8217; examination of the genetics of 250 labradors. The team looked for pieces of genetic code that were common in overweight dogs. <\/p>\n<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">They picked out one gene in particular &#8211; called DENND1B &#8211; that was associated with a higher body mass in the labradors. And when they searched through a library of genetic information from thousands of humans, they discovered that the same gene was associated with a higher body mass in people, too. <\/p>\n<p class=\"ssrcss-1q0x1qg-Paragraph e1jhz7w10\">Before this study of labrador genetics, Dr Raffan said, &#8220;no one suspected that gene  had anything to do with obesity&#8221;.<\/p>\n","protected":false},"excerpt":{"rendered":"&#8220;By studying dogs, we&#8217;ve honed in on some interesting new biology here,&#8221; explained lead researcher Dr Eleanor Raffan&hellip;\n","protected":false},"author":2,"featured_media":243871,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3846],"tags":[267,70,16,15],"class_list":{"0":"post-243870","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-genetics","8":"tag-genetics","9":"tag-science","10":"tag-uk","11":"tag-united-kingdom"},"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@uk\/114808923291326823","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts\/243870","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/comments?post=243870"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts\/243870\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/media\/243871"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/media?parent=243870"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/categories?post=243870"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/tags?post=243870"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}