{"id":275189,"date":"2025-07-19T16:45:36","date_gmt":"2025-07-19T16:45:36","guid":{"rendered":"https:\/\/www.europesays.com\/uk\/275189\/"},"modified":"2025-07-19T16:45:36","modified_gmt":"2025-07-19T16:45:36","slug":"gene-editing-offers-transformative-solution-to-saving-endangered-species","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/uk\/275189\/","title":{"rendered":"Gene editing offers transformative solution to saving endangered species"},"content":{"rendered":"

\"Gene<\/p>\n

Pink pigeons feeding. Credit: Carl Jones<\/p>\n

Gene editing technologies\u2014such as those used in agriculture and de-extinction projects\u2014can be repurposed to offer what an international team of scientists is calling a transformative solution for restoring genetic diversity and saving endangered species.<\/p>\n

In a new Nature Reviews Biodiversity Perspective article, “Genome engineering in biodiversity conservation and restoration,” the authors explore the promises, challenges and ethical considerations of genome engineering<\/a>, and propose an approach for its implementation into biodiversity conservation<\/a>.<\/p>\n

They argue that gene editing<\/a> could recover lost genetic diversity in species at risk of extinction using historical samples, such as DNA from museum collections<\/a>, biobanks and related species.<\/p>\n

The multidisciplinary team of conservation geneticists and biotechnologists is co-led by Prof Cock van Oosterhout at the University of East Anglia (UEA) and Dr. Stephen Turner from Colossal Biosciences, in collaboration with the Colossal Foundation, the Durrell Institute of Conservation and Ecology (University of Kent), Globe Institute (University of Copenhagen), Mauritius Wildlife Foundation (MWF), the Mauritius National Parks and Conservation Service (NPCS), and Durrell Wildlife Trust.<\/p>\n

“We’re facing the fastest environmental change in Earth’s history, and many species have lost the genetic variation needed to adapt and survive,” said Prof van Oosterhout.<\/p>\n

“Gene engineering provides a way to restore that variation, whether it’s reintroducing DNA variation that has been lost from immune-system genes that we can retrieve from museum specimens or borrowing climate-tolerance genes from closely related species<\/a>.<\/p>\n

“To ensure the long-term survival of threatened species, we argue that it is essential to embrace new technological advances alongside traditional conservation approaches.”<\/p>\n

\"Gene<\/p>\n

Baby pink pigeon. Credit: Jim Groombridge<\/p>\n

Conservation successes such as captive breeding and habitat protection often focus on boosting population numbers<\/a> but do little to replenish the gene variants lost when a species’ numbers crash.<\/p>\n

As populations rebound, they can remain trapped with a diminished genetic variation<\/a> and a high load of harmful mutations, a phenomenon known as genomic erosion. Without intervention, species that recovered from a population crash may remain genetically compromised, with reduced resilience to future threats like new diseases or shifting climates.<\/p>\n

One example of this is the pink pigeon, whose population has been brought back from the brink of extinction\u2014from about 10 individuals to a population now of more than 600 birds\u2014by decades of captive-breeding<\/a> and reintroduction efforts in Mauritius.<\/p>\n

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Several of the authors have studied the pigeon’s genetics to reveal that, despite its recovery, it continues to experience substantial genomic erosion and is likely to go extinct in the next 50 to 100\u2009years. The next challenge is to restore the genetic diversity it has lost, enabling it to adapt to future environmental change\u2014genome engineering could make this possible.<\/p>\n

The technology is already common in agriculture: crops resistant to pests and drought cover millions of hectares worldwide. More recently, announcements of plans to bring extinct species back to life have further highlighted its potential.<\/p>\n

“The same technological advances that allow us to introduce genes of mammoths into the genome of an elephant can be harnessed to rescue species teetering on the brink of extinction,” said Dr. Beth Shapiro, Chief Science Officer at Colossal Biosciences. “It is our responsibility to reduce the extinction risk faced today by thousands of species.”<\/p>\n

\"Gene<\/p>\n

Pink pigeon squab. Credit: Carl Jones<\/p>\n

The scientists outline three key applications for gene editing in conservation:<\/p>\n