{"id":306399,"date":"2025-07-31T10:55:11","date_gmt":"2025-07-31T10:55:11","guid":{"rendered":"https:\/\/www.europesays.com\/uk\/306399\/"},"modified":"2025-07-31T10:55:11","modified_gmt":"2025-07-31T10:55:11","slug":"why-rare-genetic-diseases-are-not-so-rare-in-india","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/uk\/306399\/","title":{"rendered":"Why rare genetic diseases are not so rare in India"},"content":{"rendered":"<p><img decoding=\"async\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2025\/07\/123017651.jpg\" alt=\"\"\/><\/p>\n<p>Thousands of years of endogamy may have shaped genetic disease risk in India. Scientists are now trying to identify those risks in communities<\/p>\n<p>In a crowded lab at the Centre for Cellular and Molecular Biology (CCMB), Kumarasamy Thangaraj points to a machine rotating test tubes that contain tissue from an animal model. The process is one step in a months-long study of a genetic mutation recently discovered in a small South Indian community. The variant, when carried by both parents, can lead to a fatal disease in the child.<br \/>The mutation likely emerged in an ancestor\u2019s genes thousands of years ago, says Thangaraj. And, because they kept marrying within their group, the variant persisted. <\/p>\n","protected":false},"excerpt":{"rendered":"Thousands of years of endogamy may have shaped genetic disease risk in India. Scientists are now trying to&hellip;\n","protected":false},"author":2,"featured_media":306400,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3846],"tags":[21371,112527,72688,8747,267,112526,76212,57538,112525,70,16,15],"class_list":{"0":"post-306399","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-genetics","8":"tag-diseases","9":"tag-endogamy-in-india","10":"tag-genetic-mutations","11":"tag-genetic-testing","12":"tag-genetics","13":"tag-kashmirs-gujjars","14":"tag-mutations","15":"tag-rare-genetic-diseases","16":"tag-rise-of-genetic-diseases-in-india","17":"tag-science","18":"tag-uk","19":"tag-united-kingdom"},"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@uk\/114947484970853380","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts\/306399","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/comments?post=306399"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts\/306399\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/media\/306400"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/media?parent=306399"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/categories?post=306399"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/tags?post=306399"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}