{"id":356185,"date":"2025-08-19T07:04:10","date_gmt":"2025-08-19T07:04:10","guid":{"rendered":"https:\/\/www.europesays.com\/uk\/356185\/"},"modified":"2025-08-19T07:04:10","modified_gmt":"2025-08-19T07:04:10","slug":"multidrug-therapy-could-help-both-the-heart-and-the-brain","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/uk\/356185\/","title":{"rendered":"Multidrug Therapy Could Help Both the Heart and the Brain"},"content":{"rendered":"<p>A groundbreaking analysis reveals that older adults taking a combination of medications for high blood pressure, cholesterol, and diabetes showed slower cognitive decline compared to those taking fewer medications.<\/p>\n<p>The impact is significant. The cognitive benefits were equivalent to being 3 years younger than the average age in the study sample.<\/p>\n<p>The research tracked over 4600 older adults without dementia, documenting their medication use and cognitive function over approximately 9 years. The findings were remarkable: Those taking all three medication classes showed notably slower decline in global cognition, particularly in semantic and working memory.<\/p>\n<p>In a deeper analysis of nearly 1900 deceased participants, those who had been taking the combination therapy showed significantly lower odds of various brain pathologies, including reduced <a href=\"https:\/\/emedicine.medscape.com\/article\/463147-overview\" class=\"cl_ref_article\" target=\"_blank\" rel=\"noopener\">atherosclerosis<\/a> and less global <a href=\"https:\/\/emedicine.medscape.com\/article\/1134817-overview\" class=\"cl_ref_article\" target=\"_blank\" rel=\"noopener\">Alzheimer&#8217;s disease<\/a> pathology.<\/p>\n<p>While these results are promising, researchers emphasize that additional studies are needed before making definitive clinical recommendations.<\/p>\n<p>This content was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.<\/p>\n","protected":false},"excerpt":{"rendered":"A groundbreaking analysis reveals that older adults taking a combination of medications for high blood pressure, cholesterol, and&hellip;\n","protected":false},"author":2,"featured_media":356186,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4315],"tags":[112655,111727,111728,18187,1545,70163,111723,51334,111724,111722,105,301,125554,111721,4326,125553,24255,111725,20903,16,15],"class_list":{"0":"post-356185","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-medication","8":"tag-alzheimer-disease-alzheimers-disease-alzheimers","9":"tag-atherosclerosis","10":"tag-atherosclerotic-disease-of-the-carotid-artery","11":"tag-blood","12":"tag-brain","13":"tag-combination-drug-therapy","14":"tag-elder-care","15":"tag-elderly","16":"tag-geriatric-medicine","17":"tag-geriatrics","18":"tag-health","19":"tag-heart","20":"tag-increased-blood-pressure","21":"tag-lipids-lipids-management","22":"tag-medication","23":"tag-mild-cognitive-impairment-minimal-cognitive-impairment-mci-mild-cognitive-impairment-mci","24":"tag-older-adults","25":"tag-senior-citizens","26":"tag-seniors","27":"tag-uk","28":"tag-united-kingdom"},"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@uk\/115054160455651040","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts\/356185","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/comments?post=356185"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts\/356185\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/media\/356186"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/media?parent=356185"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/categories?post=356185"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/tags?post=356185"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}